Strategies for the Synthesis of Tetrahydropyran-Containing Natural ProductsCLARKE, Paul A.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 175 p.Serial Issue

An asymmetric Maitland―Japp reaction: a highly enantioselective synthesis of tetrahydropyran-4-onesIQBAL, Mudassar; MISTRY, Nimesh; CLARKE, Paul A et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4949, 4960-4966 [8 p.]Article

Phosphatidylinositide-3-Kinase Inhibitors: Addressing Questions of Isoform Selectivity and Pharmacodynamic/Predictive Biomarkers in Early Clinical TrialsCLARKE, Paul A; WORKMAN, Paul.Journal of clinical oncology. 2012, Vol 30, Num 3, pp 331-333, issn 0732-183X, 3 p.Article

Synthesis of an austrodorane sesquiterpenoid core via a transannular Prins cyclizationCLARKE, Paul A; WINN, Joby.Tetrahedron letters. 2011, Vol 52, Num 13, issn 0040-4039, 1405, 1469-1472 [5 p.]Article

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: pProgress and potentialCLARKE, Paul A; TE POELE, Robert; WOOSTER, Richard et al.Biochemical pharmacology. 2001, Vol 62, Num 10, pp 1311-1336, issn 0006-2952Article

Formal total synthesis of the myxobacteria metabolite apicularen A via a transannular oxy-Michael additionHILLI, Ferdows; WHITE, Jonathan M; RIZZACASA, Mark A et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4951, 5054-5068 [16 p.]Article

Indium(III) chloride-catalyzed Mukaiyama—Michael addition: synthesis of 2, 6-anti-tetrahydropyransCHUA, Sin-Siu; ALNI, Anita; CHAN, Li-Ting Jocelyn et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4952, 5079-5082 [5 p.]Article

Studies for the enantiocontrolled preparation of substituted tetrahydropyrans: applications for the synthesis of leucascandrolide A macrolactoneWILLIAMS, David R; PLUMMER, Scott V; PATNAIK, Samarjit et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4952, 5083-5097 [16 p.]Article

Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-1 7-demethoxygeldanamycinMALONEY, Alison; CLARKE, Paul A; AHERNE, Wynne et al.Cancer research (Baltimore). 2007, Vol 67, Num 7, pp 3239-3253, issn 0008-5472, 15 p.Article

Diastereoselective synthesis of functionalized 2-methyltetrahydropyran-4-onesCLARKE, Paul A; SELLARS, Philip B; MISTRY, Nimesh et al.Tetrahedron letters. 2011, Vol 52, Num 28, issn 0040-4039, 3540, 3654-3656 [4 p.]Article

Phorboxazole synthetic studies: design, synthesis and biological evaluation of phorboxazole A and hemi-phorboxazole A related analoguesSMITH, Amos B; HOGAN, Anne-Marie L; ZHUQING LIU et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4952, 5069-5078 [11 p.]Article

The Phosphoinositide 3-Kinase Inhibitor PI-103 Downregulates Choline Kinase α Leading to Phosphocholine and Total Choline Decrease Detected by Magnetic Resonance SpectroscopyAL-SAFFAR, Nada M. S; JACKSON, L. Elizabeth; RAYNAUD, Florence I et al.Cancer research (Chicago, Ill.). 2010, Vol 70, Num 13, pp 5507-5517, issn 0008-5472, 11 p.Article

The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of CancerFOLKES, Adrian J; AHMADI, Khatereh; FRIEDMAN, Lori S et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 18, pp 5522-5532, issn 0022-2623, 11 p.Article

In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitorsSHARP, Swee Y; BOXALL, Kathy; PATTERSON, Lisa et al.Cancer research (Baltimore). 2007, Vol 67, Num 5, pp 2206-2216, issn 0008-5472, 11 p.Article

Heterocycles via intramolecular platinum-catalyzed propargylic substitutionQIREN LIANG; DE BRABANDER, Jef K.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4951, 5046-5053 [9 p.]Article

Preparation and evaluation of trisubstituted pyrimidines as phosphatidylinositol 3-kinase inhibitors. 3-Hydroxyphenol analogues and bioisosteric replacementsLARGE, Jonathan M; TORR, Jane E; WORKMAN, Paul et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 2, pp 836-851, issn 0968-0896, 16 p.Article

Stereoselective preparation of four 3-C-mannosylated D- and L-glucals from a single starting compoundLÖVYOVA, Zuzana; PARKAN, Kamil; KNIEZO, Ladislav et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4949, 4967-4979 [14 p.]Article

Asymmetric synthesis of the C(6―18) bis(tetrahydropyran)spiroacetal fragment of the lituarinesROBERTSON, Jeremy; NORTH, Christopher; SADIG, Jessie E. R et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4950, 5011-5023 [14 p.]Article

Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinasesRAYNAUD, Florence I; ECCLES, Suzanne; BJERKE, Lynn M et al.Cancer research (Baltimore). 2007, Vol 67, Num 12, pp 5840-5850, issn 0008-5472, 11 p.Article

A one-step procedure for the monoacylation of symmetrical 1,2-diolsCLARKE, Paul A; KAYALEH, Nadim E; SMITH, Martin A et al.Journal of organic chemistry. 2002, Vol 67, Num 15, pp 5226-5231, issn 0022-3263, 6 p.Article

Tetrahydropyran synthesis by palladium(II)-catalysed hydroxycarbonylation of hexenols: synthesis of (±)-diospongin A and (+)-civet cat compoundKARLUBIKOVA, Ol'ga; BABJAK, Matej; GRACZA, Tibor et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4950, 4980-4987 [9 p.]Article

Divergent approach to the polymaxenolide and pinnaic acid coresFERRARI, Frank D; LEDGARD, Andrew J; MARQUEZ, Rodolfo et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4950, 4988-4994 [8 p.]Article

FeCl₃·6H₂O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ξ-hydroxy allylic derivativesGUERINOT, Amandine; SERRA-MUNS, Anna; BENSOUSSAN, Charlélie et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4951, 5024-5033 [11 p.]Article

On the choice of Lewis acids for the Prins reaction; two total syntheses of (±)-CivetCHIO, Freda K; WARNE, Julie; DOBBS, Adrian P et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4953, 5107-5124 [19 p.]Article

A new strategy for the synthesis of substituted dihydropyrones and tetrahydropyrones via palladium-catalyzed coupling of thioestersFUWA, Haruhiko; MIZUNUMA, Kana; MATSUKIDA, Seiji et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 27-28, issn 0040-4020, 4950, 4995-5010 [17 p.]Article