Preclinical pharmacology of novel indolecarboxamide ML-970, an investigative anticancer agentRAYBURN, Elizabeth; WEI WANG; RUIWEN ZHANG et al.Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 6, pp 1423-1431, issn 0344-5704, 9 p.Article

Characterization of acute biliary hyperplasia in Fisher 344 Rats administered the Indole-3-Carbinol Analog, NSC-743380ELDRIDGE, Sandy R; COVEY, Joseph; MORRIS, Joel et al.Toxicology and applied pharmacology. 2014, Vol 281, Num 3, pp 303-309, issn 0041-008X, 7 p.Article

Increased CDA Expression/Activity in Males Contributes to Decreased Cytidine Analog Half-Life and Likely Contributes to Worse Outcomes with 5-Azacytidine or Decitabine TherapyMAHFOUZ, Reda Z; JANKOWSKA, Ania; ENGELKE, Kory J et al.Clinical cancer research (Print). 2013, Vol 19, Num 4, pp 938-948, issn 1078-0432, 11 p.Article

Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabineLAVELLE, Donald; VAITKUS, Kestis; COVEY, Joseph et al.Blood. 2012, Vol 119, Num 5, pp 1240-1247, issn 0006-4971, 8 p.Article

Electrospray LC-MS/MS quantitation, stability, and preliminary pharmacokinetics of bradykinin antagonist polypeptide B201 (NSC 710295) in the mouseWAN YONG FENG; CHAN, Kenneth K; COVEY, Joseph M et al.Journal of pharmaceutical and biomedical analysis. 2002, Vol 28, Num 3-4, pp 601-612, issn 0731-7085Article

Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detectionBEUMER, Jan H; JOSEPH, Erin; EGORIN, Merrill J et al.Journal of chromatography. B. 2006, Vol 831, Num 1-2, pp 147-155, issn 1570-0232, 9 p.Article

Chiral pharmacokinetics and inversion of enantiomers of a new quinoxaline topoisomerase IIβ poison in the ratHUI ZHENG; CHUN JIANG; CHIU, Ming H et al.Drug metabolism and disposition. 2002, Vol 30, Num 3, pp 344-348, issn 0090-9556Article

Chiral high-performance liquid chromatographic analysis of the enantiomers of XK469, a new antitumor agent, in plasma and urineHUI ZHENG; COVEY, Joseph M; TOSCA, Patricia J et al.Journal of pharmaceutical and biomedical analysis. 2002, Vol 28, Num 2, pp 287-294, issn 0731-7085Article

Modulation of Gemcitabine (2',2'-Difluoro-2'-Deoxycytidine) Pharmacokinetics, Metabolism, and Bioavailability in Mice by 3,4,5,6-TetrahydrouridineBEUMER, Jan H; EISEMAN, Julie L; PARISE, Robert A et al.Clinical cancer research. 2008, Vol 14, Num 11, pp 3529-3535, issn 1078-0432, 7 p.Article

Pharmacokinetics and tissue distribution of halofuginone (NSC 713205) in CD₂F₁ mice and Fischer 344 ratsSTECKLAIR, Kataleeya P; HAMBURGER, Deborah R; EGORIN, Merrill J et al.Cancer chemotherapy and pharmacology. 2001, Vol 48, Num 5, pp 375-382, issn 0344-5704Article

Preclinical pharmacology of the novel antitumor agent adaphostin, a tyrphostin analog that inhibits bcr/ablMAO LI; HUI WANG; HILL, Donald L et al.Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 5, pp 607-614, issn 0344-5704, 8 p.Article

Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenograftsEISEMAN, Julie L; JING LAN; LAGATTUTA, Theodore F et al.Cancer chemotherapy and pharmacology. 2005, Vol 55, Num 1, pp 21-32, issn 0344-5704, 12 p.Article

A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in miceBEUMER, Jan H; JOSEPH, Erin; EGORIN, Merrill J et al.Clinical cancer research. 2006, Vol 12, Num 19, pp 5826-5833, issn 1078-0432, 8 p.Article

Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in miceBEUMER, Jan H; EISEMAN, Julie L; PARISE, Robert A et al.Clinical cancer research. 2006, Vol 12, Num 24, pp 7483-7491, issn 1078-0432, 9 p.Article

Preclinical pharmacology of 2-methoxyantimycin A compounds as novel antitumor agentsHUI WANG; MAO LI; RHIE, Julie K et al.Cancer chemotherapy and pharmacology. 2005, Vol 56, Num 3, pp 291-298, issn 0344-5704, 8 p.Article

Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma linesPARISE, Robert A; ANYANG, Bean N; EISEMAN, Julie L et al.Cancer chemotherapy and pharmacology. 2013, Vol 71, Num 1, pp 73-83, issn 0344-5704, 11 p.Article

High performance liquid chromatographic analysis and preclinical pharmacokinetics of the heteroarotinoid antitumor agent, SHetA2YILONG ZHANG; YOUSHENG HUA; BENBROOK, Doris M et al.Cancer chemotherapy and pharmacology. 2006, Vol 58, Num 5, pp 561-569, issn 0344-5704, 9 p.Article

Plasma pharmacokinetics and tissue distribution of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) in CD2F1 mice1EGORIN, Merrill J; ZUHOWSKI, Eleanor G; ROSEN, D. Marc et al.Cancer chemotherapy and pharmacology. 2001, Vol 47, Num 4, pp 291-302, issn 0344-5704Article

Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776HOLLERAN, Julianne L; PARISE, Robert A; YELLOW-DUKE, Archibong E et al.Journal of pharmaceutical and biomedical analysis. 2010, Vol 52, Num 5, pp 714-720, issn 0731-7085, 7 p.Article

In vitro metabolism of the phosphatidylinositol 3-kinase inhibitor, wortmannin, by carbonyl reductaseHOLLERAN, Julianne L; FOURCADE, Julien; EGORIN, Merrill J et al.Drug metabolism and disposition. 2004, Vol 32, Num 5, pp 490-496, issn 0090-9556, 7 p.Article

Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in miceBEUMER, Jan H; EISEMAN, Julie L; PARISE, Robert A et al.Cancer chemotherapy and pharmacology. 2008, Vol 62, Num 3, pp 457-464, issn 0344-5704, 8 p.Article

Preclinical pharmacology of epothilone D, a novel tubulin-stabilizing antitumor agentHUI WANG; ZHI WANG; SHUYI WANG et al.Cancer chemotherapy and pharmacology. 2005, Vol 56, Num 3, pp 255-260, issn 0344-5704, 6 p.Article

Pharmacokinetics, tissue distribution, and metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (NSC 707545) in CD₂F₁ mice and Fischer 344 ratsEGORIN, Merrill J; LAGATTUTA, Theodore F; HAMBURGER, Deborah R et al.Cancer chemotherapy and pharmacology. 2002, Vol 49, Num 1, pp 7-19, issn 0344-5704Article

LC-MS/MS assay and dog pharmacokinetics of the dimeric pyrrolobenzodiazepine SJG-136 (NSC 694501)BUHROW, Sarah A; REID, Joel M; JIA, Lee et al.Journal of chromatography. B. 2006, Vol 840, Num 1, pp 56-62, issn 1570-0232, 7 p.Article

Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularineHOLLERAN, Julianne L; PARISE, Robert A; JOSEPH, Erin et al.Clinical cancer research. 2005, Vol 11, Num 10, pp 3862-3868, issn 1078-0432, 7 p.Article