Challengers for drug studies in children : CYP3A phenotiping as exampleDE WILDT, Saskia N; ITO, Shinya; KOREN, Gideon et al.Drug discovery today. 2009, Vol 14, Num 1-2, pp 6-15, issn 1359-6446, 10 p.Article

Drug metabolism for the paediatricianDE WILDT, Saskia N; TIBBOEL, D; LEEDER, J. S et al.Archives of disease in childhood. 2014, Vol 99, Num 12, pp 1137-1142, issn 0003-9888, 6 p.Article

Morphine-Induced Muscle Rigidity in a Term NeonateVAN DER LEE, Robin; CEELIE, Ilse; DE WILDT, Saskia N et al.The Annals of pharmacotherapy. 2009, Vol 43, Num 10, pp 1724-1726, issn 1060-0280, 3 p.Article

Developmental Changes in the Expression and Function of Cytochrome P450 3A Isoforms: Evidence from In Vitro and In Vivo InvestigationsINCE, Ibrahim; KNIBBE, Catherijne A. J; DANHOF, Meindert et al.Clinical pharmacokinetics. 2013, Vol 52, Num 5, pp 333-345, issn 0312-5963, 13 p.Article

¹³C-erythromycin breath test as a noninvasive measure of CYP3A activity in newborn infants : A pilot studyDE WILDT, Saskia N; BERNS, Michiel J. P; VAN DEN ANKER, John N et al.Therapeutic drug monitoring. 2007, Vol 29, Num 2, pp 225-230, issn 0163-4356, 6 p.Article

Information technology cannot guarantee patient safetyDE WILDT, Saskia N; VERZIJDEN, Ron; VAN DEN ANKER, John N et al.BMJ. British medical journal (International ed.). 2007, Vol 334, Num 7598, pp 851-852, issn 0959-8146, 2 p.Article

The effect of inflammation on drug metabolism: a focus on pediatricsVET, Nienke J; DE HOOG, Matthijs; TIBBOEL, Dick et al.Drug discovery today. 2011, Vol 16, Num 9-10, pp 435-442, issn 1359-6446, 8 p.Article

Probability of Rash Related to Gabapentin Therapy in a ChildGIJSEN, Violette M. G. J; DE WILDT, Saskia N; ITO, Shinya et al.The Annals of pharmacotherapy. 2009, Vol 43, Num 2, pp 387-389, issn 1060-0280, 3 p.Article

Tailor-made drug treatment for children creation of an infrastructure for data-sharing and population PK-PD modelingINCE, Ibrahim; DE WILDT, Saskia N; TIBBOEL, Dick et al.Drug discovery today. 2009, Vol 14, Num 5-6, pp 316-320, issn 1359-6446, 5 p.Article

Propylene Glycol-Related Delirium After Esmolol InfusionKAPITEIN, Berber; BIESMANS, Renee C. G; VAN DER SIJS, Heleen I et al.The Annals of pharmacotherapy. 2014, Vol 48, Num 7, pp 940-942, issn 1060-0280, 3 p.Article

Sample Collection, Biobanking, and AnalysisAHSMAN, Maurice J; TIBBOEL, Dick; MATHOT, Ron A. A et al.Handbook of experimental pharmacology. 2011, Vol 205, pp 203-217, issn 0171-2004, 15 p.Article

Ontogeny of midazolam glucuronidation in preterm infantsDE WILDT, Saskia N; KEARNS, Greg L; MURRY, Darryl J et al.European journal of clinical pharmacology. 2010, Vol 66, Num 2, pp 165-170, issn 0031-6970, 6 p.Article

Scaling of pharmacokinetics across paediatric populations: the lack of interpolative power of allometric modelsCELLA, Massimo; KNIBBE, Catherijne; DE WILDT, Saskia N et al.British journal of clinical pharmacology. 2012, Vol 74, Num 3, pp 525-535, issn 0306-5251, 11 p.Article

The CYP3A4^*3 Allele: Is it really rare?VAN SCHAIK, Ron H. N; DE WILDT, Saskia N; BROSENS, Rebecca et al.Clinical chemistry (Baltimore, Md.). 2001, Vol 47, Num 6, pp 1104-1106, issn 0009-9147Article

Evidence-Based Morphine Dosing for Postoperative Neonates and InfantsKREKELS, Elke H. J; TIBBOEL, Dick; DE WILDT, Saskia N et al.Clinical pharmacokinetics. 2014, Vol 53, Num 6, pp 553-563, issn 0312-5963, 11 p.Article

P450 Oxidoreductase *28 (POR*28) and Tacrolimus Disposition in Pediatric Kidney Transplant Recipients—A Pilot StudyGIJSEN, Violette M. G. J; VAN SCHAIK, Ron H. N; SOLDIN, Offie P et al.Therapeutic drug monitoring. 2014, Vol 36, Num 2, pp 152-158, issn 0163-4356, 7 p.Article

The status of paediatric medicines initiatives around the world—what has happened and what has not?HOPPU, Kalle; ANABWANI, Gabriel; GARCIA-BOURNISSEN, Facundo et al.European journal of clinical pharmacology. 2012, Vol 68, Num 1, pp 1-10, issn 0031-6970, 10 p.Article

Effect of Intravenous Paracetamol on Postoperative Morphine Requirements in Neonates and Infants Undergoing Major Noncardiac Surgery: A Randomized Controlled TrialCEELIE, Ilse; DE WILDT, Saskia N; VAN DIJK, Monique et al.JAMA, the journal of the American Medical Association. 2013, Vol 309, Num 2, pp 149-154, issn 0098-7484, 6 p.Article

CYP2D6 Polymorphisms and Codeine Analgesia in Postpartum Pain Management: A Pilot StudyVANDERVAART, Sondra; BERGER, Howard; HAYDEN, Michael R et al.Therapeutic drug monitoring. 2011, Vol 33, Num 4, pp 425-432, issn 0163-4356, 8 p.Article

Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipientsGIJSEN, Violette; MITAL, Seema; VAN SCHAIK, Ron H et al.The Journal of heart and lung transplantation. 2011, Vol 30, Num 12, pp 1352-1359, issn 1053-2498, 8 p.Article

Critical Illness Is a Major Determinant of Midazolam Clearance in Children Aged 1 Month to 17 YearsINCE, Ibrahim; DE WILDT, Saskia N; PEETERS, Mariska Y. M et al.Therapeutic drug monitoring. 2012, Vol 34, Num 4, pp 381-389, issn 0163-4356, 9 p.Article

Acute liver failure after recommended doses of acetaminophen in patients with myopathiesCEELIE, Ilse; JAMES, Laura P; GIJSEN, Violette et al.Critical care medicine. 2011, Vol 39, Num 4, pp 678-682, issn 0090-3493, 5 p.Article

Pediatric Microdose Study of [¹⁴C]Paracetamol to Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof of ConceptMOOIJ, Miriam G; VAN DUIJN, Esther; HANFF, Lidwien M et al.Clinical pharmacokinetics. 2014, Vol 53, Num 11, pp 1045-1051, issn 0312-5963, 7 p.Article

A Novel Maturation Function for Clearance of the Cytochrome P450 3A Substrate Midazolam from Preterm Neonates to AdultsINCE, Ibrahim; DE WILDT, Saskia N; WANG, Chengueng et al.Clinical pharmacokinetics. 2013, Vol 52, Num 7, pp 555-565, issn 0312-5963, 11 p.Article

The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantationDE WILDT, Saskia N; VAN SCHAIK, Ron H. N; SOLDIN, Offie P et al.European journal of clinical pharmacology. 2011, Vol 67, Num 12, pp 1231-1241, issn 0031-6970, 11 p.Article