Human Lung Immunity against Mycobacterium tuberculosis: Insights into Pathogenesis and ProtectionSCHWANDER, Stephan; DHEDA, Keertan.American journal of respiratory and critical care medicine. 2011, Vol 183, Num 6, pp 696-707, issn 1073-449X, 12 p.Article

T-cell assays for the diagnosis of latent tuberculosis infection : moving the research agenda forwardPAI, Madhukar; DHEDA, Keertan; CUNNINGHAM, Jane et al.Lancet. Infectious diseases (print). 2007, Vol 7, Num 6, pp 428-438, issn 1473-3099, 11 p.Article

Immune Reconstitution Inflammatory Syndrome in HIV-Infected Patients Receiving Antiretroviral Therapy : Pathogenesis, Clinical Manifestations and ManagementDHASMANA, Devesh J; DHEDA, Keertan; RAVN, Pernille et al.Drugs (Basel). 2008, Vol 68, Num 2, pp 191-208, issn 0012-6667, 18 p.Article

Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting?ROOK, Graham A. W; DHEDA, Keertan; ZUMLA, Alimuddin et al.Vaccine. 2005, Vol 23, Num 17-18, pp 2115-2120, issn 0264-410X, 6 p.Conference Paper

Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?THERON, Grant; PETER, Jonny; DOWDY, David et al.Lancet. Infectious diseases (print). 2014, Vol 14, Num 6, pp 527-532, issn 1473-3099, 6 p.Article

Sputum induction to aid diagnosis of smear-negative or sputum-scarce tuberculosis in adults in HIV-endemic settingsPETER, Jonathan G; THERON, Grant; SINGH, Nevanda et al.The European respiratory journal. 2014, Vol 43, Num 1, pp 185-194, issn 0903-1936, 10 p.Article

Scoring systems using chest radiographic features for the diagnosis of pulmonary tuberculosis in adults: a systematic reviewPINTO, Lancelot M; PAI, Madhukar; DHEDA, Keertan et al.The European respiratory journal. 2013, Vol 42, Num 2, pp 480-494, issn 0903-1936, 15 p.Article

Comparative Utility of Cytokine Levels and Quantitative RD-1-Specific T Cell Responses for Rapid Immunodiagnosis of Tuberculous MeningitisPATEL, Vinod B; SINGH, Ravesh; CONNOLLY, Cathy et al.Journal of clinical microbiology (Print). 2011, Vol 49, Num 11, pp 3971-3976, issn 0095-1137, 6 p.Article

Outcome of HIV-associated tuberculosis in the era of highly active antiretroviral therapyDHEDA, Keertan; LAMPE, Fiona C; JOHNSON, Margaret A et al.The Journal of infectious diseases. 2004, Vol 190, Num 9, pp 1670-1676, issn 0022-1899, 7 p.Article

Tuberculosis in association with HIV/AIDS emerges as a major nonobstetric cause of maternal mortality in Sub-Saharan AfricaGRANGE, John; ADHIKARI, Miriam; AHMED, Yusuf et al.International journal of gynaecology and obstetrics. 2010, Vol 108, Num 3, pp 181-183, issn 0020-7292, 3 p.Article

Xpert MTB/RIF as a Measure of Sputum Bacillary Burden: Variation by HIV Status and ImmunosuppressionHANRAHAN, Colleen F; THERON, Grant; BASSETT, Jean et al.American journal of respiratory and critical care medicine. 2014, Vol 189, Num 11, pp 1426-1434, issn 1073-449X, 9 p.Article

Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosisGANDHI, Neel R; NUNN, Paul; DHEDA, Keertan et al.Lancet (British edition). 2010, Vol 375, Num 9728, pp 1830-1843, issn 0140-6736, 14 p.Article

Lung remodeling in pulmonary tuberculosisDHEDA, Keertan; BOOTH, Helen; HUGGETT, Jim F et al.The Journal of infectious diseases. 2005, Vol 192, Num 7, pp 1201-1210, issn 0022-1899, 10 p.Article

Regulatory T Cells Attenuate Mycobacterial Stasis in Alveolar and Blood-derived Macrophages from Patients with TuberculosisSEMPLE, Patricia L; BINDER, Anke B; DAVIDS, Malika et al.American journal of respiratory and critical care medicine. 2013, Vol 187, Num 11, pp 1249-1258, issn 1073-449X, 10 p.Article

Validation of housekeeping genes for normalizing RNA expression in real-time PCRDHEDA, Keertan; HUGGETT, Jim F; BUSTIN, Stephen A et al.BioTechniques. 2004, Vol 37, Num 1, pp 112-119, issn 0736-6205, 6 p.Article

Scientific dogmas, paradoxes and mysteries of latent Mycobacterium tuberculosis infectionZUMLA, Alimuddin; ATUN, Rifat; MAEURER, Markus et al.TM & IH. Tropical medicine & international health. 2011, Vol 16, Num 1, pp 79-83, issn 1360-2276, 5 p.Article

Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan AfricaMIGLIORI, Giovanni Battista; DHEDA, Keertan; CENTIS, Rosella et al.TM & IH. Tropical medicine & international health. 2010, Vol 15, Num 9, pp 1052-1066, issn 1360-2276, 15 p.Article

Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell countDHEDA, Keertan; LALVANI, Ajit; MILLER, Robert F et al.AIDS (London). 2005, Vol 19, Num 17, pp 2038-2041, issn 0269-9370, 4 p.Article

Evaluation of the Xpert MTB/RIF Assay for the Diagnosis of Pulmonary Tuberculosis in a High HIV Prevalence SettingTHERON, Grant; PETER, Jonny; PAI, Madhukar et al.American journal of respiratory and critical care medicine. 2011, Vol 184, Num 1, pp 132-140, issn 1073-449X, 9 p.Article

Cerebrospinal T-Cell Responses Aid in the Diagnosis of Tuberculous Meningitis in a Human Immunodeficiency Virus― and Tuberculosis-Endemic PopulationPATEL, Vinod B; SINGH, Ravesh; CONNOLLY, Cathy et al.American journal of respiratory and critical care medicine. 2010, Vol 182, Num 4, pp 569-577, issn 1073-449X, 9 p.Article

HIV-1 Infection Impairs the Bronchoalveolar T-Cell Response to MycobacteriaKALSDORF, Barbara; SCRIBA, Thomas J; WOOD, Kathryn et al.American journal of respiratory and critical care medicine. 2009, Vol 180, Num 12, pp 1262-1270, issn 1073-449X, 9 p.Article

Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trialTHERON, Grant; ZIJENAH, Lynn; DOWDY, David et al.Lancet (British edition). 2014, Vol 383, Num 9915, pp 424-435, issn 0140-6736, 12 p.Article

The identification of tuberculosis biomarkers in human urine samplesYOUNG, Brandy L; MLAMLA, Zandile; GQAMANA, Putuma P et al.The European respiratory journal. 2014, Vol 43, Num 6, pp 1719-1729, issn 0903-1936, 11 p.Article

Do adjunct tuberculosis tests, when combined with Xpert MTB/RIF, improve accuracy and the cost of diagnosis in a resource-poor setting?THERON, Grant; POORAN, Anil; DHEDA, Keertan et al.The European respiratory journal. 2012, Vol 40, Num 1, pp 161-168, issn 0903-1936, 8 p.Article

Within-Subject Variability and Boosting of T-Cell Interferon-γ Responses after Tuberculin Skin TestingVAN ZYL-SMIT, Richard N; PAI, Madhukar; DHEDA, Keertan et al.American journal of respiratory and critical care medicine. 2009, Vol 180, Num 1, pp 49-58, issn 1073-449X, 10 p.Article