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au.\*:("DONATO, Nicholas J")

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Abrogation of signal transducer and activator of transcription 3 reactivation after src kinase inhibition results in synergistic antitumor effectsJOHNSON, Faye M; SAIGAL, Babita; TRAN, Hai et al.Clinical cancer research. 2007, Vol 13, Num 14, pp 4233-4244, issn 1078-0432, 12 p.Article

Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cellsJOHNSON, Faye M; SAIGAL, Babita; TALPAZ, Moshe et al.Clinical cancer research. 2005, Vol 11, Num 19, pp 6924-6932, issn 1078-0432, 9 p., 1Article

Sensitivity to topoisomerase I inhibitors and cisplatin is associated with epidermal growth factor receptor expression in human cervical squamous carcinoma ME180 sublinesLING, Yi-He; DONATO, Nicholas J; PEREZ-SOLER, Roman et al.Cancer chemotherapy and pharmacology. 2001, Vol 47, Num 6, pp 473-480, issn 0344-5704Article

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosisHANSHI SUN; KAPURIA, Vaibhav; PETERSON, Luke F et al.Blood. 2011, Vol 117, Num 11, pp 3151-3162, issn 0006-4971, 12 p.Article

Inhibition of Src expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse modelTREVINO, Jose G; SUMMY, Justin M; LESSLIE, Donald P et al.The American journal of pathology. 2006, Vol 168, Num 3, pp 962-972, issn 0002-9440, 11 p.Article

Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cellsBARTHOLOMEUSZ, Geoffrey A; TALPAZ, Moshe; KAPURIA, Vaibhav et al.Blood. 2007, Vol 109, Num 8, pp 3470-3478, issn 0006-4971, 9 p.Article

Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activityKAPURIA, Vaibhav; PETERSON, Luke F; HOLLIS SHOWALTER, H. D et al.Biochemical pharmacology. 2011, Vol 82, Num 4, pp 341-349, issn 0006-2952, 9 p.Article

Phase I clinical and pharmacodynamic evaluation of oral CI-1033 in patients with refractory cancerZINNER, Ralph G; NEMUNAITIS, John; EISEMAN, Irene et al.Clinical cancer research. 2007, Vol 13, Num 10, pp 3006-3014, issn 1078-0432, 9 p.Article

Superior therapeutic profile of poly-L-glutamic acid-paclitaxel copolymer compared with Taxol in xenogeneic compartmental models of human ovarian carcinomaAUZENNE, Edmond; DONATO, Nicholas J; CHUN LI et al.Clinical cancer research. 2002, Vol 8, Num 2, pp 573-581, issn 1078-0432Article

A Small Molecule Deubiquitinase Inhibitor Increases Localization of Inducible Nitric Oxide Synthase to the Macrophage Phagosome and Enhances Bacterial KillingBURKHOLDER, Kristin M; PERRY, Jeffrey W; WOBUS, Christiane E et al.Infection and immunity. 2011, Vol 79, Num 12, pp 4850-4857, issn 0019-9567, 8 p.Article

Degrasyn activates proteasomal-dependent degradation of c-MycBARTHOLOMEUSZ, Geoffrey; TALPAZ, Moshe; BORNMANN, William et al.Cancer research (Baltimore). 2007, Vol 67, Num 8, pp 3912-3918, issn 0008-5472, 7 p.Article

Down-regulation of interleukin-3/granulocyte-macrophage colony-stimulating factor receptor 3-chain in BCR-ABL+ human leukemic cells: association with loss of cytokine-mediated Stat-5 activation and protection from apoptosis after BCR-ABL inhibitionDONATO, Nicholas J; WU, Ji Y; LING ZHANG et al.Blood. 2001, Vol 97, Num 9, pp 2846-2853, issn 0006-4971Article

Antileukemic effects of AMPK activators on BCR-ABL―expressing cellsVAKANA, Eliza; ALTMAN, Jessica K; GLASER, Heather et al.Blood. 2011, Vol 118, Num 24, pp 6399-6402, issn 0006-4971, 4 p.Article

Targets and effectors of the cellular response to aurora kinase inhibitor MK-0457 (VX-680) in imatinib sensitive and resistant chronic myelogenous leukemiaDONATO, Nicholas J; DEXING FANG; HANSHI SUN et al.Biochemical pharmacology. 2010, Vol 79, Num 5, pp 688-697, issn 0006-2952, 10 p.Article

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell ApoptosisKAPURIA, Vaibhav; PETERSON, Luke F; DEXING FANG et al.Cancer research (Chicago, Ill.). 2010, Vol 70, Num 22, pp 9265-9276, issn 0008-5472, 12 p.Article

Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancerSHIN, Dong M; DONATO, Nicholas J; CLAYMAN, Gary et al.Clinical cancer research. 2001, Vol 7, Num 5, pp 1204-1213, issn 1078-0432Article

Tyrphostin-like compounds with ubiquitin modulatory activity as possible therapeutic agents for multiple myelomaZHENGHONG PENG; PAL, Ashutosh; DONGMEI HAN et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 23, pp 7194-7204, issn 0968-0896, 11 p.Article

Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN KinaseJI WU; FENG MENG; DONATO, Nicholas J et al.Journal of the National Cancer Institute. 2008, Vol 100, Num 13, pp 926-939, issn 0027-8874, 14 p.Article

Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cellsJI WU; FENG MENG; LU, Henry et al.Blood. 2008, Vol 111, Num 7, pp 3821-3829, issn 0006-4971, 9 p.Article

Imatinib mesylate resistance through BCR-ABL independence in chronic myelogenous leukemiaDONATO, Nicholas J; WU, Ji Y; TALPAZ, Moshe et al.Cancer research (Baltimore). 2004, Vol 64, Num 2, pp 672-677, issn 0008-5472, 6 p.Article

BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571DONATO, Nicholas J; JI YUAN WU; STAPLEY, Jonathan et al.Blood. 2003, Vol 101, Num 2, pp 690-698, issn 0006-4971, 9 p.Article

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