What are the properties that make an antibiotic acceptable for therapy of community-acquired pneumonia?DRUSANO, George L.Journal of antimicrobial chemotherapy (Print). 2011, Vol 66, issn 0305-7453, iii61-iii67, SUP3Article

Pharmacodynamics of ceftaroline fosamil for complicated skin and skin structure infection: rationale for improved anti-methicillin-resistant Staphylococcus aureus activityDRUSANO, George L.Journal of antimicrobial chemotherapy (Print). 2010, Vol 65, issn 0305-7453, iv33-iv39, SUP4Article

Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection : Clinical Implications of an Extended-Infusion Dosing StrategyLODISE, Thomas P; LOMAESTRO, Ben; DRUSANO, George L et al.Clinical infectious diseases. 2007, Vol 44, Num 3, pp 357-363, issn 1058-4838, 7 p.Article

Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapyLOUIE, Arnold; DEZIEL, Mark R; WEIGUO LIU et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 8, pp 2661-2667, issn 0066-4804, 7 p.Article

Comparative pharmacokinetic analysis by standard two-stage method versus nonparametric population modelingTAM, Vincent H; PRESTON, Sandra L; DRUSANO, George L et al.Pharmacotherapy. 2003, Vol 23, Num 12, pp 1545-1549, issn 0277-0008, 5 p.Article

Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic TargetMARTINEZ, Marilyn N; PAPICH, Mark G; DRUSANO, George L et al.Antimicrobial agents and chemotherapy. 2012, Vol 56, Num 6, pp 2795-2805, issn 0066-4804, 11 p.Article

Pharmacodynamic evidence that ciprofloxacin failure against tuberculosis is not due to poor microbial kill but to rapid emergence of resistanceGUMBO, Tawanda; LOUIE, Arnold; DEZIEL, Mark R et al.Antimicrobial agents and chemotherapy. 2005, Vol 49, Num 8, pp 3178-3181, issn 0066-4804, 4 p.Article

Predicting efficacy of antiinfectives with pharmacodynamics and Monte Carlo simulationBRADLEY, John S; DUDLEY, Michael N; DRUSANO, George L et al.The Pediatric infectious disease journal. 2003, Vol 22, Num 11, pp 982-992, issn 0891-3668, 11 p.Article

Telavancin Penetration into Human Epithelial Lining Fluid Determined by Population Pharmacokinetic Modeling and Monte Carlo SimulationLODISE, Thomas P; GOTFRIED, Mark; BARRIERE, Steven et al.Antimicrobial agents and chemotherapy. 2008, Vol 52, Num 7, pp 2300-2304, issn 0066-4804, 5 p.Article

Application of antimicrobial pharmacodynamic concepts into clinical practice: Focus on β-lactam antibiotics : Insights from the society of infectious diseases pharmacistsLODISE, Thomas P; LOMAESTRO, Ben M; DRUSANO, George L et al.Pharmacotherapy. 2006, Vol 26, Num 9, pp 1320-1332, issn 0277-0008, 13 p.Article

Pharmacodynamics of Cidofovir for Vaccinia Virus Infection in an In Vitro Hollow-Fiber Infection Model SystemMCSHARRY, James J; DEZIEL, Mark R; ZAGER, Kris et al.Antimicrobial agents and chemotherapy. 2009, Vol 53, Num 1, pp 129-135, issn 0066-4804, 7 p.Article

Prediction of the Pharmacodynamically Linked Variable of Oseltamivir Carboxylate for Influenza A Virus Using an In Vitro Hollow-Fiber Infection Model SystemMCSHARRY, James J; QINGMEI WENG; BROWN, Ashley et al.Antimicrobial agents and chemotherapy. 2009, Vol 53, Num 6, pp 2375-2381, issn 0066-4804, 7 p.Article

Sex differences in CYP3A activity using intravenous and oral midazolamCHEN, Maylee; LEI MA; DRUSANO, George L et al.Clinical pharmacology and therapeutics. 2006, Vol 80, Num 5, pp 531-538, issn 0009-9236, 8 p.Article

Explaining the poor bacteriologic eradication rate of single-dose ceftriaxone in group a streptococcal tonsillopharyngitis : A reverse engineering solution using pharmacodynamic modelingBLUMER, Jeffrey L; REED, Michael D; KAPLAN, Edward L et al.Pediatrics (Evanston). 2005, Vol 116, Num 4, pp 927-932, issn 0031-4005, 6 p.Article

Optimizing antimicrobial pharmacodynamics: Dosage strategies for meropenemMATTOES, Holly M; KUTI, Joseph L; DRUSANO, George L et al.Clinical therapeutics. 2004, Vol 26, Num 8, pp 1187-1198, issn 0149-2918, 12 p.Article

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs : an updateMOUTON, Johan W; DUDLEY, Michael N; CARS, Otto et al.Journal of antimicrobial chemotherapy (Print). 2005, Vol 55, Num 5, pp 601-607, issn 0305-7453, 7 p.Article

Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosaTAM, Vincent H; LOUIE, Arnold; LOMAESTRO, Ben M et al.Pharmacotherapy. 2003, Vol 23, Num 3, pp 291-295, issn 0277-0008, 5 p.Article

Dose proportional inhibition of HIV-1 replication by mycophenolic acid and synergistic inhibition in combination with abacavir, didanosine, and tenofovirHOSSAIN, Mohammad M; COULL, Jason J; DRUSANO, George L et al.Antiviral research. 2002, Vol 55, Num 1, pp 41-52, issn 0166-3542Article

Determination of antibiotic dosage adjustments in patients with renal impairment: elements for successPATEL, Nimish; SCHEETZ, Marc H; DRUSANO, George L et al.Journal of antimicrobial chemotherapy (Print). 2010, Vol 65, Num 11, pp 2285-2290, issn 0305-7453, 6 p.Article

The relationship between quinolone exposures and resistance amplification is characterized by an inverted U : a new paradigm for optimizing pharmacodynamics to counterselect resistanceTAM, Vincent H; LOUIE, Arnold; DEZIEL, Mark R et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 2, pp 744-747, issn 0066-4804, 4 p.Article

Relationship between fluoroquinolone area under the curve: Minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumoniaDRUSANO, George L; PRESTON, Sandra L; FOWLER, Cynthia et al.The Journal of infectious diseases. 2004, Vol 189, Num 9, pp 1590-1597, issn 0022-1899, 8 p.Article

Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulationLODISE, Thomas P; LOMAESTRO, Ben; RODVOLD, Keith A et al.Antimicrobial agents and chemotherapy. 2004, Vol 48, Num 12, pp 4718-4724, issn 0066-4804, 7 p.Article

Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and EndocarditisBHAVNANI, Sujata M; RUBINO, Christopher M; AMBROSE, Paul G et al.Clinical infectious diseases. 2010, Vol 50, Num 12, pp 1568-1574, issn 1058-4838, 7 p.Article

Pharmacodynamics of caspofungin in a murine model of systemic candidiasis : Importance of persistence of caspofungin in tissues to understanding drug activityLOUIE, Arnold; DEZIEL, Mark; WEIGUO LIU et al.Antimicrobial agents and chemotherapy. 2005, Vol 49, Num 12, pp 5058-5068, issn 0066-4804, 11 p.Article

Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infectionLOUIE, Arnold; KAW, Pamela; WEIGUO LIU et al.Antimicrobial agents and chemotherapy. 2001, Vol 45, Num 3, pp 845-851, issn 0066-4804Article