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SB 242084, a selective and brain penetrant 5-HT_2C receptor antagonistKENNETT, G. A; WOOD, M. D; FORBES, I. T et al.Neuropharmacology. 1997, Vol 36, Num 4-5, pp 609-620, issn 0028-3908Article

Model studies on a synthetically facile series of N-substituted phenyl-N'-pyridin-3-yl ureas leading to 1-(3-pyridylcarbamoyl) indolines that are potent and selective 5-HT_2C/2B receptor antagonistsBROMIDGE, S. M; DABBS, S; SAUNDERS, D. V et al.Bioorganic & medicinal chemistry. 1999, Vol 7, Num 12, pp 2767-2773, issn 0968-0896Article

(±)11-amino-2,6-dimethyl-1,2,3,4-tetrahydro-6H-quinindolin-1-one, a novel GABA_A modulator with potential anxiolytic activityBLACKBURN, T. P; BOLTON, D; FORBES, I. T et al.Bioorganic & medicinal chemistry letters (Print). 1994, Vol 4, Num 2, pp 279-284, issn 0960-894XArticle

Syntheses of functionalised pyrido[2,3-b]indolesFORBES, I. T; JOHNSON, C. N; THOMPSON, M et al.Journal of the Chemical Society. Perkin transactions. I. 1992, Num 2, pp 275-281, issn 0300-922XArticle

SB-243213; a selective 5-HT_2C receptor inverse agonist with improved anxiolytic profile : Lack of tolerance and withdrawal anxietyWOOD, M. D; REAVILL, C; RILEY, G et al.Neuropharmacology. 2001, Vol 41, Num 2, pp 186-199, issn 0028-3908Article

Functional characterisation of the human cloned 5-HT₇ receptor (long form); antagonist profile of SB-258719THOMAS, D. R; GITTINS, S. A; COLLIN, L. L et al.British journal of pharmacology. 1998, Vol 124, Num 6, pp 1300-1306, issn 0007-1188Article

6-Chloro-5-methyl-l-[[2-[(2-methyl-3-pyridyl)oxy] -5-pyridyl]carbamoyl]-indoline (sb-242084) : The first selective and brain penetrant 5-HT_2C receptor antagonistBROMIDGE, S. M; DUCKWORTH, M; WOOD, M. D et al.Journal of medicinal chemistry (Print). 1997, Vol 40, Num 22, pp 3494-3496, issn 0022-2623Article

Biarylcarbamoylindolines are novel and selective 5-HT_2C receptor inverse agonists : Identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agentBROMIDGE, S. M; DABBS, S; MULHOLLAND, K. R et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 6, pp 1123-1134, issn 0022-2623Article

1-[2-[(Heteroaryloxy)heteroaryl]carbamoyl]indolines : Novel and selective 5-HT_2C receptor inverse agonists with potential as antidepressant/anxiolytic agentsBROMIDGE, S. M; DABBS, S; HOLLAND, V et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 16, pp 1863-1866, issn 0960-894XArticle

CCR2B receptor antagonists : Conversion of a weak HTS hit to a potent lead compoundFORBES, I. T; COOPER, D. G; MOORES, K et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 16, pp 1803-1806, issn 0960-894XArticle

5-Methyl-1-(3-pyridylcarbomoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole : a novel 5-HT_2C/5-HT_2B receptor antagonist with improved affinity, selectivity, and oral activityFORBES, I. T; HAM, P; BOOTH, D. H et al.Journal of medicinal chemistry (Print). 1995, Vol 38, Num 14, pp 2524-2530, issn 0022-2623Article

A novel, potent, and selective 5-HT₇ antagonist : (R)-3-2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonylphenol (SB-269970)LOVELL, P. J; BROMIDGE, S. M; COLLIN, L. L et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 3, pp 342-345, issn 0022-2623Article

1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT_2C receptor inverse agonistsBROMIDGE, S. M; DAVIES, S; LIGHTOWLER, S et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 16, pp 1867-1870, issn 0960-894XArticle

(R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)propyl]benzenesulfonamide : The first selective 5-HT₇ receptor antagonistFORBES, I. T; DABBS, S; RILEY, G. J et al.Journal of medicinal chemistry (Print). 1998, Vol 41, Num 5, pp 655-657, issn 0022-2623Article

Synthesis, biological activity, and molecular modeling studies of selective 5-HT_2C/2B receptor antagonistsFORBES, I. T; DABBS, S; BLACKBURN, T. P et al.Journal of medicinal chemistry (Print). 1996, Vol 39, Num 25, pp 4966-4977, issn 0022-2623Article

N-(1-Methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea : a novel, high-affinity 5-HT_2B receptor antagonistFORBES, I. T; JONES, G. E; MURPHY, O. E et al.Journal of medicinal chemistry (Print). 1995, Vol 38, Num 6, pp 855-857, issn 0022-2623Article

Synthesis and evaluation of a series of aryl[e]fused pyrazolo[4,3-c]pyridines with potential anxiolytic activityFORBES, I. T; JONHSON, C. N; JONES, G. E et al.Journal of medicinal chemistry (Print). 1990, Vol 33, Num 9, pp 2640-2645, issn 0022-2623Article

Characterization of a CNS penetrant, selective M₁ muscarinic receptor agonist, 77-LH-28-1LANGMEAD, C. J; AUSTIN, N. E; JONES, G. A et al.British journal of pharmacology. 2008, Vol 154, Num 5, pp 1104-1115, issn 0007-1188, 12 p.Article

In vitro and in vivo profile of SB 206553, a potent 5-HT_2C/-HT_2B receptor antagonist with anxiolytic-like propertiesKENNETT, G. A; WOOD, M. D; BLACKBURN, T. P et al.British journal of pharmacology. 1996, Vol 117, Num 3, pp 427-434, issn 0007-1188Article

N-(1-methyl-5-indolyl)-N'-(3-pyridyl)urea hydrochloride : the first selective 5-HT_1C receptor antagonistFORBES, I. T; KENNETT, G; MURPHY, O. E et al.Journal of medicinal chemistry (Print). 1993, Vol 36, Num 8, pp 1104-1107, issn 0022-2623Article

Synthesis and potential anxiolytic activity of 4-amino-pyrido[2,3-b]indolesBOLTON, D; FORBES, I. T; HAYWARD, C. J et al.Bioorganic & medicinal chemistry letters (Print). 1993, Vol 3, Num 10, issn 0960-894X, 1902, 1941-1946Article

Hydroxylamine-alkyne cyclisations. A new method for the synthesis of cyclic nitronesFOX, M. E; HOLMES, A. B; FORBES, I. T et al.Tetrahedron letters. 1992, Vol 33, Num 48, pp 7421-7424, issn 0040-4039Article

Hydroxylamine-alkyne cyclisations. Synthesis of the seven-membered lactam structure proposed for (±)-acacialactamFOX, M. E; HOMES, A. B; FORBES, I. T et al.Tetrahedron letters. 1992, Vol 33, Num 48, pp 7425-7428, issn 0040-4039Article