Simple procedures for blinded sample size adjustment that do not affect the type I error rateKIESER, Meinhard; FRIEDE, Tim.Statistics in medicine. 2003, Vol 22, Num 23, pp 3571-3581, issn 0277-6715, 11 p.Article

Blinded continuous monitoring of nuisance parameters in clinical trialsFRIEDE, Tim; MILLER, Frank.Applied statistics. 2012, Vol 61, Num 4, pp 601-618, issn 0035-9254, 18 p.Article

RejoinderFRIEDE, Tim; KIESER, Meinhard.Biometrical journal. 2006, Vol 48, Num 4, issn 0323-3847, p.558Article

On the inappropriateness of an EM algorithm based procedure for blinded sample size re-estimationFRIEDE, Tim; KIESER, Meinhard.Statistics in medicine. 2002, Vol 21, Num 2, pp 165-176, issn 0277-6715Article

Sample size recalculation in internal pilot study designs : A reviewFRIEDE, Tim; KIESER, Meinhard.Biometrical journal. 2006, Vol 48, Num 4, pp 537-555, issn 0323-3847, 19 p.Article

Sample size adjustment in clinical trials for proving equivalenceFRIEDE, Tim; KIESER, Meinhard.Drug information journal. 2001, Vol 35, Num 4, pp 1401-1408, issn 0092-8615Article

A comparison of procedures for adaptive choice of location tests in flexible two-stage designsFRIEDE, Tim; KIESER, Meinhard; NEUHÄUSER, Markus et al.Biometrical journal. 2003, Vol 45, Num 3, pp 292-310, issn 0323-3847, 19 p.Article

A bootstrap procedure for adaptive selection of the test statistic in flexible two-stage designsKIESER, Meinhard; SCHNEIDER, Brit; FRIEDE, Tim et al.Biometrical journal. 2002, Vol 44, Num 5, pp 641-652, issn 0323-3847, 12 p.Article

A comparison of peritonitis in polycystic and non-polycystic patients on peritoneal dialysisPANDYA, Bhavna K; FRIEDE, Tim; WILLIAMS, John D et al.Peritoneal dialysis international. 2004, Vol 24, Num 1, pp 79-81, issn 0896-8608, 3 p.Article

A comparison of methods for adaptive sample size adjustmentFRIEDE, Tim; KIESER, Meinhard.Statistics in medicine. 2001, Vol 20, Num 24, pp 3861-3873, issn 0277-6715Conference Paper

Blinded Sample Size Reestimation in Non-Inferiority Trials with Binary EndpointsFRIEDE, Tim; MITCHELL, Charles; MÜLLER-VELTEN, Günther et al.Biometrical journal. 2007, Vol 49, Num 6, pp 903-916, issn 0323-3847, 14 p.Article

Trends in annualized relapse rates in relapsing-remitting multiple sclerosis and consequences for clinical trial designNICHOLAS, Richard; STRAUBE, Sebastian; SCHMIDLI, Heinz et al.Multiple sclerosis. 2011, Vol 17, Num 10, pp 1211-1217, issn 1352-4585, 7 p.Article

Time-patterns of annualized relapse rates in randomized placebo-controlled clinical trials in relapsing multiple sclerosis: A systematic review and meta-analysisNICHOLAS, Richard; STRAUBE, Sebastian; SCHMIDLI, Heinz et al.Multiple sclerosis. 2012, Vol 18, Num 9, pp 1290-1296, issn 1352-4585, 7 p.Article

Blinded sample size reassessment in non-inferiority and equivalence trialsFRIEDE, Tim; KIESER, Meinhard.Statistics in medicine. 2003, Vol 22, Num 6, pp 995-1007, issn 0277-6715, 13 p.Conference Paper

Explaining temporal trends in annualised relapse rates in placebo groups of randomised controlled trials in relapsing multiple sclerosis: systematic review and meta-regressionSTEINVORTH, Simon M; RÖVER, Christian; SCHNEIDER, Simon et al.Multiple sclerosis. 2013, Vol 19, Num 12, pp 1580-1586, issn 1352-4585, 7 p.Article

A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosisCHATAWAY, Jeremy; NICHOLAS, Richard; TODD, Susan et al.Multiple sclerosis. 2011, Vol 17, Num 1, pp 81-88, issn 1352-4585, 8 p.Article

Effect of the left internal mammary artery to the left anterior descending artery on mortality and morbidity after combined coronary and valve operationsKARTHIK, Shishir; SRINIVASAN, Arun K; GRAYSON, Antony D et al.The Annals of thoracic surgery. 2005, Vol 80, Num 1, pp 163-169, issn 0003-4975, 7 p.Article

Effect and feasibility of controlled rewarming after moderate hypothermia in stroke patients with malignant infarction of the middle cerebral arterySTEINER, Thorsten; FRIEDE, Tim; ASCHOFF, Alfred et al.Stroke (1970). 2001, Vol 32, Num 12, pp 2833-2835, issn 0039-2499Article

Validation and reliability of the neuropathic pain scale (NPS) in multiple sclerosisROG, David J; NURMIKKO, Turo J; FRIEDE, Tim et al.The Clinical journal of pain. 2007, Vol 23, Num 6, pp 473-481, issn 0749-8047, 9 p.Article

Randomized, controlled trial of cannabis- based medicine in central pain in multiple sclerosisROG, David J; NURMIKKO, Turo J; FRIEDE, Tim et al.Neurology. 2005, Vol 65, Num 6, pp 812-819, issn 0028-3878, 8 p.Article

Pro-Active Call Center Treatment Support (PACCTS) to improve glucose control in type 2 diabetes: A randomized controlled trialYOUNG, Robert J; TAYLOR, Jean; GIBSON, J. Martin et al.Diabetes care. 2005, Vol 28, Num 2, pp 278-282, issn 0149-5992, 5 p.Article

A Comparison of Methods for Adaptive Treatment SelectionFRIEDE, Tim; STALLARD, Nigel.Biometrical journal. 2008, Vol 50, Num 5, pp 767-781, issn 0323-3847, 15 p.Conference Paper

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohortMOLLENHAUER, Brit; TRAUTMANN, Ellen; KLEIN, Christine et al.Neurology. 2013, Vol 81, Num 14, pp 1226-1234, issn 0028-3878, 9 p.Article

Therapeutic Apheresis in Pediatric Patients with Acute CNS Inflammatory Demyelinating DiseaseKOZIOLEK, Michael; MÜHLHAUSEN, Johannes; FRIEDE, Tim et al.Blood purification. 2013, Vol 36, Num 2, pp 92-97, issn 0253-5068, 6 p.Article

Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancyGROSS, Oliver; LICHT, Christoph; KONRAD, Martin et al.Kidney international. 2012, Vol 81, Num 5, pp 494-501, issn 0085-2538, 8 p.Article