The efficacy of cefditoren pivoxil in the treatment of lower respiratory tract infections, with a focus on the per-pathogen bacteriologic response in infections caused by Streptococcus pneumoniae and Haemophilus influenzae : A pooled analysis of seven clinical trialsGRANIZO, Juan Jose; GIMENEZ, Maria-José; BARBERAN, José et al.Clinical therapeutics. 2006, Vol 28, Num 12, pp 2061-2069, issn 0149-2918, 9 p.Article

Levofloxacin plus rifampicin conservative treatment of 25 early staphylococcal infections of osteosynthetic devices for rigid internal fixationBARBERAN, José; AGUILAR, Lorenzo; GIMENEZ, Maria-José et al.International journal of antimicrobial agents. 2008, Vol 32, Num 2, pp 154-157, issn 0924-8579, 4 p.Article

Azithromycin iv pharmacodynamic parameters predicting Streptococcus pneumoniae killing in epithelial lining fluid versus serum : an in vitro pharmacodynamic simulationSEVILLANO, David; ALOU, Luis; AGUILAR, Lorenzo et al.Journal of antimicrobial chemotherapy (Print). 2006, Vol 57, Num 6, pp 1128-1133, issn 0305-7453, 6 p.Article

Effects of antimicrobials on the competitive growth of Streptococcus pneumoniae : a pharmacodynamic in vitro model approach to selection of resistant populationsSEVILLANO, David; AGUILAR, Lorenzo; ALOU, Luis et al.Journal of antimicrobial chemotherapy (Print). 2006, Vol 58, Num 4, pp 794-801, issn 0305-7453, 8 p.Article

Urine bactericidal activity against resistant Escherichia coli in an in vitro pharmacodynamic model simulating urine concentrations obtained after 2000/125 mg sustained-release co-amoxiclav and 400 mg norfloxacin administrationALOU, Luis; AGUILAR, Lorenzo; SEVILLANO, David et al.Journal of antimicrobial chemotherapy (Print). 2006, Vol 57, Num 4, pp 714-719, issn 0305-7453, 6 p.Article

Genotypic versus phenotypic characterization, with respect to susceptibility and identification, of 17 clinical isolates of Staphylococcus lugdunensisMATEO, Maria; MAESTRE, Juan-Ramon; AGUILAR, Lorenzo et al.Journal of antimicrobial chemotherapy (Print). 2005, Vol 56, Num 2, pp 287-291, issn 0305-7453, 5 p.Article

Evolution of Clonal and Susceptibility Profiles of Serotype 19A Streptococcus pneumoniae among Invasive Isolates from Children in Spain, 1990 to 2008TARRAGO, David; AGUILAR, Lorenzo; GARCIA, Raquel et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 5, pp 2297-2302, issn 0066-4804, 6 p.Article

Urine Bactericidal Activity against Escherichia coli Isolates Exhibiting Different Resistance Phenotypes/Genotypes in an In Vitro Pharmacodynamic Model Simulating Urine Concentrations Obtained after Oral Administration of a 400-Milligram Single Dose of Cefditoren-PivoxilSEVILLANO, David; AGUILAR, Lorenzo; ALOU, Luis et al.Antimicrobial agents and chemotherapy. 2008, Vol 52, Num 3, pp 1184-1186, issn 0066-4804, 3 p.Article

Bactericidal activity of amoxicillin against non-susceptible Streptococcus pneumoniae in an in vitro pharmacodynamic model simulating the concentrations obtained with the 2000/125 mg sustained-release co-amoxiclav formulationSEVILLANO, David; CALVO, Almudena; GIMENEZ, Maria-José et al.Journal of antimicrobial chemotherapy (Print). 2004, Vol 54, Num 6, pp 1148-1151, issn 0305-7453, 4 p.Article

Urinary concentrations and bactericidal activity against amoxicillin-nonsusceptible strains of Escherichia coli with single-dose, oral, sustained-release amoxicillin/clavulanic acid : A phase I, open-label, noncomparative clinical trial in healthy volunteersPONTE, Carmen; GRACIA, Matilde; GIMENEZ, Maria-José et al.Clinical therapeutics. 2005, Vol 27, Num 7, pp 1043-1049, issn 0149-2918, 7 p.Article

Genotypic versus Phenotypic Characterization, with Respect to β-Lactam Susceptibility, of Haemophilus influenzae Isolates Exhibiting Decreased Susceptibility to β-Lactam Resistance MarkersSEVILLANO, David; GIMENEZ, Maria-José; CERCENADO, Emilia et al.Antimicrobial agents and chemotherapy. 2009, Vol 53, Num 1, pp 267-270, issn 0066-4804, 4 p.Article

Influence of the β-lactam resistance phenotype on the cefuroxime versus cefditoren susceptibility of Streptococcus pneumoniae and Haemophilus influenzae recovered from children with acute otitis mediaFENOLL, Asuncion; AGUILAR, Lorenzo; ROBLEDO, Olga et al.Journal of antimicrobial chemotherapy (Print). 2007, Vol 60, Num 2, pp 323-327, issn 0305-7453, 5 p.Article

A pharmacodynamic approach to antimicrobial activity in serum and epithelial lining fluid against in vivo-selected Streptococcus pneumoniae mutants and association with clinical failure in pneumoniaALOU, Luis; GIMENEZ, Maria-José; SEVILLANO, David et al.Journal of antimicrobial chemotherapy (Print). 2006, Vol 58, Num 2, pp 349-358, issn 0305-7453, 10 p.Article

Is there a pharmacodynamic need for the use of continuous versus intermittent infusion with ceftazidime against Pseudomonas aeruginosa? An in vitro pharmacodynamic modelALOU, Luis; AGUILAR, Lorenzo; SEVILLANO, David et al.Journal of antimicrobial chemotherapy (Print). 2005, Vol 55, Num 2, pp 209-213, issn 0305-7453, 5 p.Article

In vitro combined effect of co-amoxiclav concentrations achievable in serum after a 2000/125 mg oral dose, and polymorphonuclear neutrophils against strains of Streptococcus pneumoniae exhibiting decreased susceptibility to amoxicillinAMORES, Raquel; ALOU, Luis; GIMENEZ, Maria José et al.International journal of antimicrobial agents. 2004, Vol 24, Num 1, pp 79-82, issn 0924-8579, 4 p.Article

Does acetaminophen interfere in the antibiotic treatment of acute otitis media caused by a penicillin-resistant pneumococcus strain? A gerbil modelPONTE, Carmen; PARRA, Araceli; CENJOR, Carlos et al.Pediatric research. 2003, Vol 54, Num 6, pp 913-918, issn 0031-3998, 6 p.Article

Optimal dose of amoxicillin in treatment of otitis media caused by a penicillin-resistant pneumococcus strain in the gerbil modelPARRA, Araceli; PONTE, Carmen; CENJOR, Carlos et al.Antimicrobial agents and chemotherapy. 2002, Vol 46, Num 3, pp 859-862, issn 0066-4804Article

Is it possible to achieve bacterial eradication in otitis media with effusion by empirical antibiotic high doses and concomitant administration of acetaminophen? A microbiological and pharmacological study in the gerbil modelPARRA, Araceli; PONTE, Carmen; CENJOR, Carlos et al.International journal of antimicrobial agents. 2003, Vol 22, Num 5, pp 508-515, issn 0924-8579, 8 p.Article

Quality and antioxidant properties on sweet cherries as affected by preharvest salicylic and acetylsalicylic acids treatmentsGIMENEZ, María José; VALVERDE, Juan Miguel; VALERO, Daniel et al.Food chemistry. 2014, Vol 160, pp 226-232, issn 0308-8146, 7 p.Article

Susceptibility of Recently Collected Spanish Pneumococci Nonsusceptible to Oral Penicillin from Serotypes Not Included in the 7-Valent Conjugate VaccineFENOLL, Asunción; AGUILAR, Lorenzo; GIMENEZ, María-José et al.Antimicrobial agents and chemotherapy. 2010, Vol 54, Num 6, pp 2696-2698, issn 0066-4804, 3 p.Article

In vitro interference of tigecycline at subinhibitory concentrations on biofilm development by Enterococcus faecalisRAMON MAESTRE, Juan; AGUILAR, Lorenzo; MATEO, María et al.Journal of antimicrobial chemotherapy (Print). 2012, Vol 67, Num 5, pp 1155-1158, issn 0305-7453, 4 p.Article

Activity of simulated serum concentrations of daptomycin versus vancomycin during the first 24 h of treatment in the presence of physiological albumin concentrations against vancomycin-susceptible, -tolerant or -intermediate-resistant Staphylococcus aureusTORRICO, Martha; AGUILAR, Lorenzo; SEVILLANO, David et al.International journal of antimicrobial agents (Print). 2011, Vol 37, Num 4, pp 332-338, issn 0924-8579, 7 p.Article

Variations in serotypes and susceptibility of adult non-invasive Streptococcus pneumoniae isolates between the periods before (May 2000-May 2001) and 10 years after (May 2010-May 2011 ) introduction of conjugate vaccines for child immunisation in SpainFENOLL, Asunción; AGUILAR, Lorenzo; GIMENEZ, María-José et al.International journal of antimicrobial agents (Print). 2012, Vol 40, Num 1, pp 18-23, issn 0924-8579, 6 p.Article

Influence of different resistance traits on the competitive growth of Haemophilus influenza in antibiotic-free medium and selection of resistant populations by different β-lactams: an in vitro pharmacodynamic approachGONZALEZ, Natalia; AGUILAR, Lorenzo; ALOU, Luis et al.Journal of antimicrobial chemotherapy (Print). 2009, Vol 63, Num 6, pp 1215-1222, issn 0305-7453, 8 p.Article

Efficacy of Simulated Cefditoren versus Amoxicillin-Clavulanate Free Concentrations in Countering Intrastrain ftsI Gene Diffusion in Haemophilus influenzaeGONZALEZ, Natalia; AGUILAR, Lorenzo; SEVILLANO, David et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 6, pp 2788-2794, issn 0066-4804, 7 p.Article