Hybrid Compound Design To Overcome the Gatekeeper T338M Mutation in cSrc^#GETLIK, Matthaus; GRÜTTER, Christian; SIMARD, Jeffrey R et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 13, pp 3915-3926, issn 0022-2623, 12 p.Article

Displacement Assay for the Detection of Stabilizers of Inactive Kinase Conformations^tKLÜTER, Sabine; GRÜTTER, Christian; NAQVI, Tabassum et al.Journal of medicinal chemistry (Print). 2010, Vol 53, Num 1, pp 357-367, issn 0022-2623, 11 p.Article

ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK InhibitorsHEUCKMANN, Johannes M; HÖLZEL, Michael; RAUH, Daniel et al.Clinical cancer research (Print). 2011, Vol 17, Num 23, pp 7394-7401, issn 1078-0432, 8 p.Article

Structural insights into how irreversible inhibitors can overcome drug resistance in EGFRMICHALCZYK, Anja; KLÜTER, Sabine; RODE, Haridas B et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 7, pp 3482-3488, issn 0968-0896, 7 p.Article

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancerPEIFER, Martin; FERNANDEZ-CUESTA, Lynnette; MENON, Roopika et al.Nature genetics. 2012, Vol 44, Num 10, pp 1104-1110, issn 1061-4036, 7 p.Article

Structure-based design, synthesis and biological evaluation of N-pyrazole, N'-thiazole urea inhibitors of MAP kinase p38αGETLIK, Matthaus; GRÜTTER, Christian; SIMARD, Jeffrey R et al.European journal of medicinal chemistry. 2012, Vol 48, pp 1-15, issn 0223-5234, 15 p.Article

An Invariant Surface Patch on the TRIM5α PRYSPRY Domain Is Required for Retroviral Restriction but Dispensable for Capsid BindingSEBASTIAN, Sarah; GRÜTTER, Christian; STRAMBIO DE CASTILLIA, Caterina et al.Journal of virology. 2009, Vol 83, Num 7, pp 3365-3373, issn 0022-538X, 9 p.Article