A randomised, double-blind phase III study of pazopanib in patients with advanced and/or metastatic renal cell carcinoma: Final overall survival results and safety updateSTERNBERG, Cora N; HAWKINS, Robert E; MCCANN, Lauren et al.European journal of cancer (1990). 2013, Vol 49, Num 6, pp 1287-1296, issn 0959-8049, 10 p.Article

Expanded subpopulation of FoxP3⁺ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced TregsELKORD, Eyad; SHARMA, Smita; BURT, Deborah J et al.Clinical immunology (Orlando, Fla. Print). 2011, Vol 140, Num 3, pp 218-222, issn 1521-6616, 5 p.Article

The role of extracellular spacer regions in the optimal design of chimeric immune receptors: Evaluation of four different scFvs and antigensGUEST, Ryan D; HAWKINS, Robert E; EMBLETON, M. J et al.Journal of immunotherapy (1997). 2005, Vol 28, Num 3, pp 203-211, issn 1524-9557, 9 p.Article

Modulation of Lymphocyte Regulation for Cancer Therapy: A Phase II Trial of Tremelimumab in Advanced Gastric and Esophageal AdenocarcinomaRALPH, Christy; ELKORD, Eyad; BURT, Deborah J et al.Clinical cancer research (Print). 2010, Vol 16, Num 5, pp 1662-1672, issn 1078-0432, 11 p.Article

Pazopanib in Locally Advanced or Metastatic Renal Cell Carcinoma: Results of a Randomized Phase III TrialSTERNBERG, Cora N; DAVIS, Ian D; ZARBA, Juan J et al.Journal of clinical oncology. 2010, Vol 28, Num 6, pp 1061-1068, issn 0732-183X, 8 p.Article

Gene therapy of patient-derived T lymphocytes to target and eradicate colorectal hepatic metastasesSHEEN, Aali J; IRLAM, Joely; KIRILLOVA, Natalia et al.Diseases of the colon & rectum. 2003, Vol 46, Num 6, pp 793-804, issn 0012-3706, 12 p.Conference Paper

In vitro effect of IL-2 in combination with pazopanib or sunitinib on lymphocytes function and apoptosis of RCC cellsSHABLAK, Alaaeldin; GILHAM, David E; HAWKINS, Robert E et al.Expert opinion on pharmacotherapy. 2014, Vol 15, Num 11, pp 1489-1499, issn 1465-6566, 11 p.Article

Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4)ELKORD, Eyad; DANGOOR, Adam; BURT, Deborah J et al.Cancer immunology and immunotherapy. 2009, Vol 58, Num 10, pp 1657-1667, issn 0340-7004, 11 p.Article

Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responsesHARROP, Richard; DRURY, Noel; HAWKINS, Robert E et al.Cancer immunology and immunotherapy. 2008, Vol 57, Num 7, pp 977-986, issn 0340-7004, 10 p.Article

CD8 T-cell recognition of human 5T4 oncofetal antigenSMYTH, Lucy J. C; ELKORD, Eyad; DRIJFHOUT, Jan W et al.International journal of cancer. 2006, Vol 119, Num 7, pp 1638-1647, issn 0020-7136, 10 p.Article

Killing of non-hodgkin lymphoma cells by autologous CD19 engineered T cellsCHEADLE, Eleanor J; GILHAM, David E; THISTLETHWAITE, Fiona C et al.British journal of haematology. 2005, Vol 129, Num 3, pp 322-332, issn 0007-1048, 11 p.Article

Amplification of epidermal growth factor receptor gene in renal cell carcinomaEL-HARIRY, Iman; POWLES, Thomas; BARTHEL, Friederike et al.European journal of cancer (1990). 2010, Vol 46, Num 5, pp 859-862, issn 0959-8049, 4 p.Article

Development of Adoptive Cell Therapy for Cancer: A Clinical PerspectiveHAWKINS, Robert E; GILHAM, David E; DEBETS, Reno et al.Human gene therapy. 2010, Vol 21, Num 6, pp 665-672, issn 1043-0342, 8 p.Article

Eradication of Established B-cell Lymphoma by CD19-specific Murine T Cells is Dependent on Host Lymphopenic Environment and Can be Mediated by CD4⁺ and CD8⁺ T CellsCHEADLE, Eleanor J; HAWKINS, Robert E; BATHA, Hayley et al.Journal of immunotherapy (1997). 2009, Vol 32, Num 3, pp 207-218, issn 1524-9557, 12 p.Article

Vaccination of Patients With Metastatic Renal Cancer With Modified Vaccinia Ankara Encoding the Tumor Antigen 5T4 (TroVax) Given Alongside Interferon-αHAWKINS, Robert E; MACDERMOTT, Catriona; SHABLAK, Alaaeldin et al.Journal of immunotherapy (1997). 2009, Vol 32, Num 4, pp 424-429, issn 1524-9557, 6 p.Article

The combination of cyclophosphamide and human T cells genetically engineered to target CD19 can eradicate established B-cell lymphomaCHEADLE, Eleanor J; GILHAM, David E; HAWKINS, Robert E et al.British journal of haematology. 2008, Vol 142, Num 1, pp 65-68, issn 0007-1048, 4 p.Article

Adoptive transfer of anti-idiotypic T cells cure mice of disseminated B cell lymphomaARMSTRONG, Anne C; DERMIME, Said; MULRYAN, Kate et al.Journal of immunotherapy (1997). 2004, Vol 27, Num 3, pp 227-231, issn 1524-9557, 5 p.Article

Targeted immunotherapy of cancer with CAR T cells: achievements and challengesLIPOWSKA-BHALLA, Grazyna; GILHAM, David E; HAWKINS, Robert E et al.Cancer immunology and immunotherapy. 2012, Vol 61, Num 7, pp 953-962, issn 0340-7004, 10 p.Article

High-dose Interleukin-2 Can Produce a High Rate of Response and Durable Remissions in Appropriately Selected Patients With Metastatic Renal CancerSHABLAK, Alaaeldin; SIKAND, Kanwal; SHANKS, Jonathan H et al.Journal of immunotherapy (1997). 2011, Vol 34, Num 1, pp 107-112, issn 1524-9557, 6 p.Article

MVA―5T4-induced immune responses are an early marker of efficacy in renal cancer patientsHARROP, Richard; SHINGLER, William H; NAYLOR, Stuart et al.Cancer immunology and immunotherapy. 2011, Vol 60, Num 6, pp 829-837, issn 0340-7004, 9 p.Article

Vaccination of Metastatic Renal Cancer Patients with MVA-5T4: A Randomized, Double-Blind, Placebo-Controlled Phase III StudyAMATO, Robert J; HAWKINS, Robert E; GOONEWARDENA, Madusha et al.Clinical cancer research (Print). 2010, Vol 16, Num 22, pp 5539-5547, issn 1078-0432, 9 p.Article

Adoptive transfer of T_reg depleted autologous T cells in advanced renal cell carcinomaTHISTLETHWAITE, Fiona C; ELKORD, Eyad; GRIFFITHS, Richard W et al.Cancer immunology and immunotherapy. 2008, Vol 57, Num 5, pp 623-634, issn 0340-7004, 12 p.Article

Primary polyclonal human T lymphocytes targeted to carcino-embryonic antigens and neural cell adhesion molecule tumor antigens by CD3ζ-based chimeric immune receptorsGILHAM, David E; O'NEIL, Allison; HUGHES, Chris et al.Journal of immunotherapy (1997). 2002, Vol 25, Num 2, pp 139-151, issn 1524-9557Article

Cancer vaccines and immunotherapyDERMIME, Said; ARMSTRONG, Anne; HAWKINS, Robert E et al.British medical bulletin. 2002, Vol 62, pp 149-162, issn 0007-1420, 14 p.Article

Tremelimumab (anti-CTLA4) mediates immune responses mainly by direct activation of T effector cells rather than by affecting T regulatory cellsKHAN, Sameena; BURT, Deborah J; RALPH, Christy et al.Clinical immunology (Orlando, Fla. Print). 2011, Vol 138, Num 1, pp 85-96, issn 1521-6616, 12 p.Article