Ascorbate-induced lipid peroxidation and the binding of ³H-dihydroalprenololHEIKKILA, R. E.European journal of pharmacology. 1983, Vol 93, Num 1-2, pp 79-85, issn 0014-2999Article

Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sourcesHEIKKILA, R. E.European journal of pharmacology. 1985, Vol 117, Num 1, pp 131-133, issn 0014-2999Article

Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: specific inhibitors of dopamine uptakeHEIKKILA, R. E; MANZINO, L.European journal of pharmacology. 1984, Vol 103, Num 3-4, pp 241-248, issn 0014-2999Article

Interactions of D1 and D2 dopamine receptors on the ipsilateral vs. contralateral side in rats with unilateral lesions of the dopaminergic nigrotriatal pathwaySONSALLA, P. K; MANZINO, L; HEIKKILA, R. E et al.The Journal of pharmacology and experimental therapeutics. 1988, Vol 247, Num 1, pp 180-185, issn 0022-3565Article

Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridiniumVYAS, I; HEIKKILA, R. E; NICKLAS, W. J et al.Journal of neurochemistry. 1986, Vol 46, Num 5, pp 1501-1507, issn 0022-3042Article

The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in miceSONSALLA, P. K; HEIKKILA, R. E.European journal of pharmacology. 1986, Vol 129, Num 3, pp 339-345, issn 0014-2999Article

Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in miceHEIKKILA, R. E; HESS, A; DUVOISIN, R. C et al.Science (Washington, D.C.). 1984, Vol 224, Num 4656, pp 1451-1453, issn 0036-8075Article

The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in miceSONSALLA, P. K; HEIKKILA, R. E.European journal of pharmacology. 1986, Vol 129, Num 3, pp 339-345, issn 0014-2999Article

1-Methyl-4-phenylpyridine (MPP⁺) is toxic to mesencephalic dopamine neurons in cultureMYTILINEOU, C; COHEN, G; HEIKKILA, R. E et al.Neuroscience letters. 1985, Vol 57, Num 1, pp 19-24, issn 0304-3940Article

Studies on the stability of ³H-dopamine, ³Hapomorphine and ³H-ADTN: effects of sodium ascorbate and EDTACABBAT, F. S; MANZINO, L; HEIKKILA, R. E et al.Research communications in chemical pathology and pharmacology. 1985, Vol 47, Num 3, pp 333-343, issn 0034-5164Article

Behavioral correlations of dopamine receptor activationGERSHANIK, O; HEIKKILA, R. E; DUVOISIN, R. C et al.Neurology. 1983, Vol 33, Num 11, pp 1489-1492, issn 0028-3878Article

Prevention of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic toxicity in mice by MDL 72145, a selective inhibitor of MAO-BVICTORIA KINDT, M; HEIKKILA, R. E.Life sciences (1973). 1986, Vol 38, Num 16, pp 1459-1462, issn 0024-3205Article

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineNICKLAS, W. J; VYAS, I; HEIKKILA, R. E et al.Life sciences (1973). 1985, Vol 36, Num 26, pp 2503-2508, issn 0024-3205Article

Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and methamphetamine in several strains of miceSONSALLA, P. K; HEIKKILA, R. E.Progress in neuro-psychopharmacology & biological psychiatry. 1988, Vol 12, Num 2-3, pp 345-354, issn 0278-5846Conference Paper

Ascorbate-induced lipid peroxidation and inhibition of [³H]spiroperidol binding in neostriatal membrane preparationsHEIKKILA, R. E; CABBAT, F. S.Journal of neurochemistry. 1983, Vol 41, Num 5, pp 1384-1392, issn 0022-3042Article

Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transportMAYER, R. A; KINDT, M. V; HEIKKILA, R. E et al.Journal of neurochemistry. 1986, Vol 47, Num 4, pp 1073-1079, issn 0022-3042Article

Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine and related compounds on the uptake of [³H]3,4-dihydroxyphenylethylamine and [³H]5-hydroxytryptamine in neostriatal synaptosomal preparationsHEIKKILA, R. E; YOUNGSTER, S. K; MANZINO, L et al.Journal of neurochemistry. 1985, Vol 44, Num 1, pp 310-313, issn 0022-3042Article

Dopaminergic toxicity after the stereotaxic administration of the 1-methyl-4-phenylpyridinium ion (MPP⁺) to ratsHEIKKILA, R. E; NICKLAS, W. J; DUVOISIN, R. C et al.Neuroscience letters. 1985, Vol 59, Num 1, pp 135-140, issn 0304-3940Article

Potentiation by the tetraphenylboron anion of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its pyridinium metaboliteHEIKKILA, R. E; HWANG, J; OFORI, S et al.Journal of neurochemistry. 1990, Vol 54, Num 3, pp 743-750, issn 0022-3042, 8 p.Article

Continuous levodopa infusions to treat complex dystonia in Parkinson's diseaseSAGE, J. I; MCHALE, D. M; SONSALLA, P et al.Neurology. 1989, Vol 39, Num 7, pp 888-891, issn 0028-3878Article

Isolated jejunal pouches for levodopa delivery in Parkinsonian patients with «on»off». Successful experimental model in dogsSAGE, J. I; TROOSKIN, S; SCHUH, L et al.Clinical neuropharmacology. 1988, Vol 11, Num 3, pp 212-220, issn 0362-5664Article

Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicityHEIKKILA, R. E; NICKLAS, W. J; VYAS, I et al.Neuroscience letters. 1985, Vol 62, Num 3, pp 389-394, issn 0304-3940Article

Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicitySONSALLA, P. K; NICKLAS, W. J; HEIKKILA, R. E et al.Science (Washington, D.C.). 1989, Vol 243, Num 4889, pp 398-400, issn 0036-8075Article

Evaluation of the biological activity of several analogs of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineYOUNGSTER, S. K; SONSALLA, P. K; HEIKKILA, R. E et al.Journal of neurochemistry. 1987, Vol 48, Num 3, pp 929-934, issn 0022-3042Article

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration to C57-black mice leads to parallel decrements in neostriatal dopamine content and tyrosine hydroxylase activityMAYER, R. A; WALTERS, A. S; HEIKKILA, R. E et al.European journal of pharmacology. 1986, Vol 120, Num 3, pp 375-377, issn 0014-2999Article