Ascl2 and 11 p15.5 amplification in colorectal cancerJUBB, Adrian M; HOEFLICH, Klaus P; HAVERTY, Peter M et al.Gut. 2011, Vol 60, Num 11, pp 1606-1607, issn 0017-5749, 2 p.Article

Pak1 Kinase Links ErbB2 to β-Catenin in Transformation of Breast Epithelial CellsARIAS-ROMERO, Luis E; VILLAMAR-CRUZ, Olga; MIN HUANG et al.Cancer research (Chicago, Ill.). 2013, Vol 73, Num 12, pp 3671-3682, issn 0008-5472, 12 p.Article

Regulation of ERK3/MAPK6 expression by BRAFHOEFLICH, Klaus P; EBY, Michael T; FORREST, William F et al.International journal of oncology. 2006, Vol 29, Num 4, pp 839-849, issn 1019-6439, 11 p.Article

In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer ModelsHOEFLICH, Klaus P; O'BRIEN, Carol; WEI ZHOU et al.Clinical cancer research (Print). 2009, Vol 15, Num 14, pp 4649-4664, issn 1078-0432, 16 p.Article

Bridging the Gap between Preclinical and Clinical Studies Using Pharmacokinetic-Pharmacodynamic Modeling: An Analysis of GDC-0973, a MEK InhibitorWONG, Harvey; VERNILLET, Laurent; HOEFLICH, Klaus P et al.Clinical cancer research (Print). 2012, Vol 18, Num 11, pp 3090-3099, issn 1078-0432, 10 p.Article

p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer ModelHOI YEE CHOW; JUBB, Adrian M; SILVIO GUTKIND, J et al.Cancer research (Chicago, Ill.). 2012, Vol 72, Num 22, pp 5966-5975, issn 0008-5472, 10 p.Article

Oncogenic BRAF is required for tumor growth and maintenance in melanoma modelsHOEFLICH, Klaus P; GRAY, Daniel C; MURRAY, Lesley J et al.Cancer research (Baltimore). 2006, Vol 66, Num 2, pp 999-1006, issn 0008-5472, 8 p.Article

P21-Activated Kinase 1 (PAK1) as a Therapeutic Target in BRAF Wild-Type MelanomaONG, Christy C; JUBB, Adrian M; HARRIS, Adrian L et al.Journal of the National Cancer Institute. 2013, Vol 105, Num 9, pp 606-615, issn 0027-8874, 10 p.Article

Intermittent Administration of MEK Inhibitor GDC-0973 plus PI3K Inhibitor GDC-0941 Triggers Robust Apoptosis and Tumor Growth InhibitionHOEFLICH, Klaus P; MERCHANT, Mark; ENGST, Stefan et al.Cancer research (Chicago, Ill.). 2012, Vol 72, Num 1, pp 210-219, issn 0008-5472, 10 p.Article

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growthHATZIVASSILIOU, Georgia; KYUNG SONG; MORALES, Tony et al.Nature (London). 2010, Vol 464, Num 7287, pp 431-435, issn 0028-0836, 5 p.Article

Antitumor Efficacy of the Novel RAF Inhibitor GDC-0879 Is Predicted by BRAF^V600E Mutational Status and Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway SuppressionHOEFLICH, Klaus P; HERTER, Sylvia; STERN, Howard et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 7, pp 3042-3051, issn 0008-5472, 10 p.Article