Recent advances in the molecular and cellular biology of chronic myeloid leukaemia : Lessons to be learned from the laboratoryHOLYOAKE, Tessa L.British journal of haematology. 2001, Vol 113, Num 1, pp 11-23, issn 0007-1048Article

Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CMLVIGNIR HELGASON, G; KARVELA, Maria; HOLYOAKE, Tessa L et al.Blood. 2011, Vol 118, Num 8, pp 2035-2043, issn 0006-4971, 9 p.Article

Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606KONIG, Heiko; HOLYOAKE, Tessa L; BHATIA, Ravi et al.Blood. 2008, Vol 111, Num 4, pp 2329-2338, issn 0006-4971, 10 p.Article

A comparison of normal and leukemic stem cell biology in chronic myeloid leukemiaJØRGENSEN, Heather G; HOLYOAKE, Tessa L.Hematological oncology. 2001, Vol 19, Num 3, pp 89-106, issn 0278-0232Article

Optimising chronic myeloid leukaemia therapy in the face of resistance to tyrosine kinase inhibitors ― A synthesis of clinical and laboratory dataIRVINE, David A; HEANEY, Nicholas B; HOLYOAKE, Tessa L et al.Blood reviews. 2010, Vol 24, Num 1, pp 1-9, issn 0268-960X, 9 p.Article

Targeted therapy in haematological malignanciesHAMILTON, Ashley; GALLIPOLI, Paolo; NICHOLSON, Emma et al.Journal of pathology (Print). 2010, Vol 220, Num 4, pp 404-418, issn 0022-3417, 15 p.Article

BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34⁺38^― cells, through activation of protein kinase CβPELLICANO, Francesca; COPLAND, Mhairi; JORGENSEN, Heather G et al.Blood. 2009, Vol 114, Num 19, pp 4186-4196, issn 0006-4971, 11 p.Article

Punish the parent not the progenyELRICK, Lucy J; JORGENSEN, Heather G; MOUNTFORA, Joanne C et al.Blood. 2005, Vol 105, Num 5, pp 1862-1866, issn 0006-4971, 5 p.Article

Isolation and therapeutic potential of human haemopoietic stem cellsCLARK, Andrew D; JØRGENSEN, Heather G; MOUNTFORD, Joanne et al.Cytotechnology (Dordrecht). 2003, Vol 41, Num 2-3, pp 111-131, issn 0920-9069, 21 p.Article

BCR-ABL fish monitoring of CML: A survey of current UK practiceDRUMMOND, Mark W; HENDRY, Lynn M; MAHER, Edward et al.British journal of haematology. 2002, Vol 119, Num 1, pp 272-273, issn 0007-1048Article

Hurdles Toward a Cure for CML: The CM L Stem CellGALLIPOLI, Paolo; ABRAHAM, Sheela A; HOLYOAKE, Tessa L et al.Hematology/oncology clinics of North America. 2011, Vol 25, Num 5, issn 0889-8588, 951-966, v [17 p.]Article

HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemiaSTRATHDEE, Gordon; SIM, Alyson; SOUTAR, Richard et al.Carcinogenesis (New York. Print). 2007, Vol 28, Num 2, pp 299-309, issn 0143-3334, 11 p.Article

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34⁺ CML cellsJØRGENSEN, Heather G; ALLAN, Elaine K; JORDANIDES, Niove E et al.Blood. 2007, Vol 109, Num 9, pp 4016-4019, issn 0006-4971, 4 p.Article

Mobilization of Ph chromosome-negative peripheral blood stem cells in chronic myeloid leukaemia patients with imatinib mesylate-induced complete cytogenetic remissionDRUMMOND, Mark W; MARIN, David; CLARK, Richard E et al.British journal of haematology. 2003, Vol 123, Num 3, pp 479-483, issn 0007-1048, 5 p.Article

Functional ABCG2 is overexpressed on primary CML CD34⁺ cells and is inhibited by imatinib mesylate. CommentaryMELO, Junia V; JORDANIDES, Niove E; JORGENSEN, Heather G et al.Blood. 2006, Vol 108, Num 4, issn 0006-4971, 1116-1117,1370-1373 [6 p.]Article

Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylateJØRGENSEN, Heather G; COPLAND, Mhairi; ALLAN, Elaine K et al.Clinical cancer research. 2006, Vol 12, Num 2, pp 626-633, issn 1078-0432, 8 p.Article

α₁-Acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571JØRGENSEN, Heather G; ELLIOTT, Moira A; ALLAN, Elaine K et al.Blood. 2002, Vol 99, Num 2, pp 713-715, issn 0006-4971Article

BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitorsCOPLAND, Mhairi; PELLICANO, Francesca; RICHMOND, Linda et al.Blood. 2008, Vol 111, Num 5, pp 2843-2853, issn 0006-4971, 11 p.Article

The use of isobaric tag peptide labeling (iTRAQ) and mass spectrometry to examine rare, primitive hematopoietic cells from patients with chronic myeloid leukemiaGRIFFITHS, Stephen D; BURTHEM, John; UNWIN, Richard D et al.Molecular biotechnology. 2007, Vol 36, Num 2, pp 81-89, issn 1073-6085, 9 p.Article

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitroGRAHAM, Susan M; JØRGENSEN, Heather G; ALLAN, Elaine et al.Blood. 2002, Vol 99, Num 1, pp 319-325, issn 0006-4971Article

Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1―BCR-ABL―JAK2 ComplexMIN CHEN; GALLIPOLI, Paolo; LAMBIE, Karen et al.Journal of the National Cancer Institute. 2013, Vol 105, Num 6, pp 405-423, issn 0027-8874, 19 p.Article

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survivalHAMILTON, Ashley; VIGNIR HELGASON, G; KOSCHMIEDER, Steffen et al.Blood. 2012, Vol 119, Num 6, pp 1501-1510, issn 0006-4971, 10 p.Article

Expression of the Transcriptional Repressor Gfi-1 Is Regulated by C/EBPα and Is Involved in Its Proliferation and Colony Formation-Inhibitory Effects in p210BCR/ABL-Expressing CellsLIDONNICI, Maria Rosa; AUDIA, Alessandra; CALABRETTA, Bruno et al.Cancer research (Chicago, Ill.). 2010, Vol 70, Num 20, pp 7949-7959, issn 0008-5472, 11 p.Article

BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemiaROY, Swagata; JORGENSEN, Heather G; ROY, Poornima et al.British journal of haematology. 2012, Vol 157, Num 4, pp 446-456, issn 0007-1048, 11 p.Article

Combined bezafibrate and medroxyprogesterone acetate have efficacy without haematological toxicity in elderly and relapsed acute myeloid leukaemia (AML)MURRAY, Jim A; KHANIM, Farhat L; HAYDEN, Rachel E et al.British journal of haematology. 2010, Vol 149, Num 1, pp 65-69, issn 0007-1048, 5 p.Article