au.\*:("HOWE, Anita Y. M")
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Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymeraseGOPALSAMY, Ariamala; MENGXIAO SHI; CISZEWSKI, Gregory et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 9, pp 2532-2534, issn 0960-894X, 3 p.Article
HCV796 : A Selective Nonstructural Protein 5B Polymerase Inhibitor with Potent Anti-Hepatitis C Virus Activity In Vitro, in Mice with Chimeric Human Livers, and in Humans Infected with Hepatitis C VirusKNETEMAN, Norman M; HOWE, Anita Y. M; CHAUDHARY, Inder et al.Hepatology (Baltimore, Md.). 2009, Vol 49, Num 3, pp 745-752, issn 0270-9139, 8 p.Article
Identification of [(naphthalene-1-carbonyl)-amino]-acetic acid derivatives as nonnucleoside inhibitors of HCV NS5B RNA dependent RNA polymeraseGOPALSAMY, Ariamala; LIM, Kitae; ELLINGBOE, John W et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 16, pp 4221-4224, issn 0960-894X, 4 p.Article
Design and synthesis of HCV agents with sequential triple inhibitory potentialsTIANMIN ZHU; FAWZI, Mahdi B; FLINT, Michael et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 17, pp 5212-5216, issn 0960-894X, 5 p.Article
Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding siteGOPALSAMY, Ariamala; CHOPRA, Rajiv; AGARWAL, Atul et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 11, pp 3052-3055, issn 0022-2623, 4 p.Article
Boceprevir versus placebo with pegylated interferon alfa-2b and ribavirin for treatment of hepatitis C virus genotype 1 in patients with HIV: a randomised, double-blind, controlled phase 2 trialSULKOWSKI, Mark; POL, Stanislas; WENNING, Larissa et al.Lancet. Infectious diseases (print). 2013, Vol 13, Num 7, pp 597-605, issn 1473-3099, 9 p.Article
Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymeraseNITTOLI, Thomas; CURRAN, Kevin; JOHNSON, Bernard et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 9, pp 2108-2116, issn 0022-2623, 9 p.Article
Virologic Resistance Analysis From a Phase 2 Study of MK-5172 Combined With Pegylated Interferon/Ribavirin in Treatment-Naive Patients With Hepatitis C Virus Genotype 1 InfectionHOWE, Anita Y. M; BLACK, Stuart; CARO, Luzelena et al.Clinical infectious diseases. 2014, Vol 59, Num 12, pp 1657-1665, issn 1058-4838, 9 p.Article
Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecyclineTUCKMAN, Margareta; PETERSEN, Peter J; HOWE, Anita Y. M et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 9, pp 3205-3211, issn 0066-4804, 7 p.Article
Molecular mechanism of a thumb domain hepatitis c virus nonnucleoside RNA-dependent RNA polymerase inhibitorHOWE, Anita Y. M; HUIMING CHENG; THOMPSON, Ian et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 12, pp 4103-4113, issn 0066-4804, 11 p.Article
Selection and Characterization of Hepatitis C Virus Replicons Dually Resistant to the Polymerase and Protease Inhibitors HCV-796 and Boceprevir (SCH 503034)FLINT, Mike; MULLEN, Stanley; DEATLY, Anne M et al.Antimicrobial agents and chemotherapy. 2009, Vol 53, Num 2, pp 401-411, issn 0066-4804, 11 p.Article
Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymeraseGOPALSAMY, Ariamala; APLASCA, Alexis; CISZEWSKI, Gregory et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 2, pp 457-460, issn 0960-894X, 4 p.Article
Diagnostic PCR analysis of the occurrence of methicillin and tetracycline resistance genes among Staphylococcus aureus isolates from phase 3 clinical trials of tigecycline for complicated skin and skin structure infectionsJONES, C. Hal; TUCKMAN, Margareta; HOWE, Anita Y. M et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 2, pp 505-510, issn 0066-4804, 6 p.Article
Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitorsGOPALSAMY, Ariamala; LIM, Kitae; DAMARLA, Murthy et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 26, pp 6603-6608, issn 0022-2623, 6 p.Article
Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymeraseHOWE, Anita Y. M; BLOOM, Johnathan; GORCZYCA, William P et al.Antimicrobial agents and chemotherapy. 2004, Vol 48, Num 12, pp 4813-4821, issn 0066-4804, 9 p.Article