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Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinasesGUOZHANG XU; LILY LEE SEARLE; GRUNINGER, Robert H et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 12, pp 3495-3499, issn 0960-894X, 5 p.Article

7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors : Design, synthesis, and biological activityHUGHES, Terry V; EMANUEL, Stuart L; O'GRADY, Harold R et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 18, pp 5130-5133, issn 0960-894X, 4 p.Article

A novel 5-[1,3,4-oxadiazol-2-yl]-N-aryl-4,6-pyrimidine diamine having dual EGFR/HER2 kinase activity : Design, synthesis, and biological activityHUGHES, Terry V; GUOZHANG XU; MIDDLETON, Steven A et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 17, pp 4896-4899, issn 0960-894X, 4 p.Article

4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluationHUGHES, Terry V; EMANUEL, Stuart L; MIDDLETON, Steven A et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 12, pp 3266-3270, issn 0960-894X, 5 p.Article

Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunitsPARRISH, Jay P; HUGHES, Terry V; HWANG, Inkyu et al.Journal of the American Chemical Society. 2004, Vol 126, Num 1, pp 80-81, issn 0002-7863, 2 p.Article

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