Mutational analysis in chronic myeloid leukemia: when and what to do?BRANFORD, Susan; HUGHES, Timothy P.Current opinion in hematology. 2011, Vol 18, Num 2, pp 111-116, issn 1065-6251, 6 p.Article

Managing imatinib resistance in chronic myeloid leukaemiaOSBORN, Michael; HUGHES, Timothy.Current opinion in hematology. 2010, Vol 17, Num 2, pp 97-103, issn 1065-6251, 7 p.Article

Molecular monitoring of BCR-ABL as a guide to clinical management in chronic myeloid leukaemiaHUGHES, Timothy; BRANFORD, Susan.Blood reviews. 2006, Vol 20, Num 1, pp 29-41, issn 0268-960X, 13 p.Article

Dasatinib or High-Dose Imatinib for Chronic-Phase Chronic Myeloid Leukemia Resistant to Imatinib at a Dose of 400 to 600 Milligrams Daily: Two-Year Follow-Up of a Randomized Phase 2 Study (START-R)KANTARJIAN, Hagop; PASQUINI, Ricardo; SHAH, Neil P et al.Cancer. 2009, Vol 115, Num 18, pp 4136-4147, issn 0008-543X, 12 p.Article

Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemiaLE COUTRE, Philipp; OTTMANN, Oliver G; KULICZKOWSKI, Kazimierz et al.Blood. 2008, Vol 111, Num 4, pp 1834-1839, issn 0006-4971, 6 p.Article

Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib : a randomized phase 2 trial. CommentarySCHIFFER, Charles A; KANTARJIAN, Hagop; SKOTNICKI, Aleksander et al.Blood. 2007, Vol 109, Num 12, issn 0006-4971, 5068-5069, 5143-5150 [10 p.]Article

Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity : higher doses of imatinib may overcome the negative impact of low OCT-1 activityWHITE, Deborah L; SAUNDERS, Verity A; PHUONG DANG et al.Blood. 2007, Vol 110, Num 12, pp 4064-4072, issn 0006-4971, 9 p.Article

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemiaO'BRIEN, Stephen G; GUILHOT, Francois; LECHNER, Klaus et al.The New England journal of medicine. 2003, Vol 348, Num 11, pp 994-1004, issn 0028-4793, 11 p.Article

A Phase I/II study of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALLTOJO, Arinobu; USUKI, Kensuke; MIYAMURA, Koichi et al.International journal of hematology. 2009, Vol 89, Num 5, pp 679-688, issn 0925-5710, 10 p.Article

BCR-ABL Messenger RNA Levels Continue to Decline in Patients with Chronic Phase Chronic Myeloid Leukemia Treated with Imatinib for More Than 5 Years and Approximately Half of All First -Line Treated Patients Have Stable Undetectable BCR-ABL Using Strict Sensitivity CriteriaBRANFORD, Susan; SEYMOUR, John F; GRIGG, Andrew et al.Clinical cancer research. 2007, Vol 13, Num 23, pp 7080-7085, issn 1078-0432, 6 p.Article

Monitoring of minimal residual disease in chronic myeloid leukemiaFADERL, Stefan; HOCHHAUS, Andreas; HUGHES, Timothy et al.Hematology/oncology clinics of North America. 2004, Vol 18, Num 3, pp ix-x, issn 0889-8588, 16 p.Article

Renal toxicity after total body irradiationBORG, Martin; HUGHES, Timothy; HORVATH, Noemi et al.International journal of radiation oncology, biology, physics. 2002, Vol 54, Num 4, pp 1165-1173, issn 0360-3016, 9 p.Article

A mild form of Mucopolysaccharidosis IIIB diagnosed with targeted next-generation sequencing of linked genomic regionsSELMER, Kaja K; GILFILLAN, Gregor D; MUNTHE, Ludvig A et al.European journal of human genetics. 2012, Vol 20, Num 1, pp 58-63, issn 1018-4813, 6 p.Article

Front-Line and Salvage Therapies With Tyrosine Kinase Inhibitors and Other Treatments in Chronic Myeloid LeukemiaCORTES, Jorge; HOCHHAUS, Andreas; HUGHES, Timothy et al.Journal of clinical oncology. 2011, Vol 29, Num 5, pp 524-531, issn 0732-183X, 8 p.Article

Impact of Baseline BCR-ABL Mutations on Response to Nilotinib in Patients With Chronic Myeloid Leukemia in Chronic PhaseHUGHES, Timothy; SAGLIO, Giuseppe; KIM, Dongho et al.Journal of clinical oncology. 2009, Vol 27, Num 25, pp 4204-4210, issn 0732-183X, 7 p.Article

Advanced Morphological and Biochemical Magnetic Resonance Imaging of Cartilage Repair Procedures in the Knee Joint at 3 TeslaWELSCH, Goetz H; MAMISCH, Tallal C; HUGHES, Timothy et al.Seminars in musculoskeletal radiology. 2008, Vol 12, Num 3, pp 196-211, issn 1089-7860, 16 p.Article

Magnetoresistive read heads for high-density data applicationsCUNTZE, Georg; HUGHES, Timothy; MAGNUSSON, Steven et al.IEEE transactions on magnetics. 2001, Vol 37, Num 5, pp 3839-3843, issn 0018-9464, 2Article

Clinical Strategies to Achieve an Early and Successful Response to Tyrosine Kinase Inhibitor TherapyHUGHES, Timothy; HOCHHAUS, Andreas.Seminars in hematology. 2009, Vol 46, Num 2, issn 0037-1963, S11-S15, SUP3Article

Intermittent Target Inhibition With Dasatinib 100 mg Once Daily Preserves Efficacy and Improves Tolerability in Imatinib-Resistant and -Intolerant Chronic-Phase Chronic Myeloid LeukemiaSHAH, Neil P; KANTARJIAN, Hagop M; KHOROSHKO, Nina et al.Journal of clinical oncology. 2008, Vol 26, Num 19, pp 3204-3212, issn 0732-183X, 9 p.Article

Optimizing Outcomes for Patients With Advanced Disease in Chronic Myelogenous LeukemiaGILES, Francis J; DEANGELO, Daniel J; BACCARANI, Michele et al.Seminars in oncology. 2008, Vol 35, Num 1, issn 0093-7754, S1-S17, SUP1Article

Measurement of in vivo BCR-ABL kinase inhibition to monitor imatinib-induced target blockade and predict response in chronic myeloid leukemiaWHITE, Deborah; SAUNDERS, Verity; GRIGG, Andrew et al.Journal of clinical oncology. 2007, Vol 25, Num 28, pp 4445-4451, issn 0732-183X, 7 p.Article

In vitro sensitivity to imatinib-induced inhibition of ABL kinase activity is predictive of molecular response in patients with de novo CMLWHITE, Deborah; SAUNDERS, Verity; LYONS, A. Bruce et al.Blood. 2005, Vol 106, Num 7, pp 2520-2526, issn 0006-4971, 7 p.Article

Clinical resistance to imatinib: mechanisms and implicationsHOCHHAUS, Andreas; HUGHES, Timothy.Hematology/oncology clinics of North America. 2004, Vol 18, Num 3, issn 0889-8588, ix, 641-656 [17 p.]Article

ANK3 gene expression in bipolar disorder and schizophreniaWIRGENES, Katrine Verena; TESLI, Martin; INDERHAUG, Elin et al.British journal of psychiatry (Print). 2014, Vol 205, Num 3, pp 244-245, issn 0007-1250, 2 p.Article

Correlation of Echocardiographic Findings With Cerebral Infarction in Elderly Adults: The AGES-Reykjavik StudyMCAREAVEY, Dorothea; VIDAL, Jean-Sébastien; LAUNER, Lenore J et al.Stroke (1970). 2010, Vol 41, Num 10, pp 2223-2228, issn 0039-2499, 6 p.Article