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Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1―BCR-ABL―JAK2 ComplexMIN CHEN; GALLIPOLI, Paolo; LAMBIE, Karen et al.Journal of the National Cancer Institute. 2013, Vol 105, Num 6, pp 405-423, issn 0027-8874, 19 p.Article

Properties of CD34⁺ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylateXIAOYAN JIANG; FORREST, Donna; PANG, Emily et al.Blood. 2010, Vol 116, Num 12, pp 2112-2121, issn 0006-4971, 10 p.Article

Punish the parent not the progenyELRICK, Lucy J; JORGENSEN, Heather G; MOUNTFORA, Joanne C et al.Blood. 2005, Vol 105, Num 5, pp 1862-1866, issn 0006-4971, 5 p.Article

BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34⁺38^― cells, through activation of protein kinase CβPELLICANO, Francesca; COPLAND, Mhairi; JORGENSEN, Heather G et al.Blood. 2009, Vol 114, Num 19, pp 4186-4196, issn 0006-4971, 11 p.Article

Isolation and therapeutic potential of human haemopoietic stem cellsCLARK, Andrew D; JØRGENSEN, Heather G; MOUNTFORD, Joanne et al.Cytotechnology (Dordrecht). 2003, Vol 41, Num 2-3, pp 111-131, issn 0920-9069, 21 p.Article

Functional ABCG2 is overexpressed on primary CML CD34⁺ cells and is inhibited by imatinib mesylate. CommentaryMELO, Junia V; JORDANIDES, Niove E; JORGENSEN, Heather G et al.Blood. 2006, Vol 108, Num 4, issn 0006-4971, 1116-1117,1370-1373 [6 p.]Article

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34⁺ CML cellsJØRGENSEN, Heather G; ALLAN, Elaine K; JORDANIDES, Niove E et al.Blood. 2007, Vol 109, Num 9, pp 4016-4019, issn 0006-4971, 4 p.Article

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitroGRAHAM, Susan M; JØRGENSEN, Heather G; ALLAN, Elaine et al.Blood. 2002, Vol 99, Num 1, pp 319-325, issn 0006-4971Article

Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylateJØRGENSEN, Heather G; COPLAND, Mhairi; ALLAN, Elaine K et al.Clinical cancer research. 2006, Vol 12, Num 2, pp 626-633, issn 1078-0432, 8 p.Article

α₁-Acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571JØRGENSEN, Heather G; ELLIOTT, Moira A; ALLAN, Elaine K et al.Blood. 2002, Vol 99, Num 2, pp 713-715, issn 0006-4971Article

Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3HOLYOAKE, Tessa L; XIAOYAN JIANG; JORGENSEN, Heather G et al.Blood. 2001, Vol 97, Num 3, pp 720-728, issn 0006-4971Article

BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemiaROY, Swagata; JORGENSEN, Heather G; ROY, Poornima et al.British journal of haematology. 2012, Vol 157, Num 4, pp 446-456, issn 0007-1048, 11 p.Article

Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosisSTRATHDEE, Gordon; HOLYOAKE, Tessa L; JORGENSEN, Heather G et al.Clinical cancer research. 2007, Vol 13, Num 17, pp 5048-5055, issn 1078-0432, 8 p.Article

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cellsHEANEY, Nicholas B; PELLICANO, Francesca; HOLYOAKE, Tessa L et al.Blood. 2010, Vol 115, Num 11, pp 2241-2250, issn 0006-4971, 10 p.Article

Uptake of synthetic Low Density Lipoprotein by leukemic stem cells — a potential stem cell targeted drug delivery strategyPEIXUN ZHOU; HATZIIEREMIA, Sophia; ELLIOTT, Moira A et al.Journal of controlled release. 2010, Vol 148, Num 3, pp 380-387, issn 0168-3659, 8 p.Article