Gene-Based Therapies for Dominant Retinopathies : AAV-Mediated Gene Therapy for the treatment of Retinal DiseaseFARRAR, G. Jane; PALFI, Arpad; KENNA, Paul F et al.Current gene therapy. 2010, Vol 10, Num 5, pp 381-388, issn 1566-5232, 8 p.Article

Influence of a Quantitative Trait Locus on Mouse Chromosome 19 to the Light-Adapted ElectroretinogramREYNOLDS, Alison L; DANCIGER, Michael; FARRAR, G. Jane et al.Investigative ophthalmology & visual science. 2008, Vol 49, Num 9, pp 4058-4063, issn 0146-0404, 6 p.Article

Sensitivity of photoreceptor-derived cell line (661W) to baculoviral p35, Z-VAD.FMK, and Fas-associated death domainTUOHY, Gearoid; MILLINGTON-WARD, Sophia; KENNA, Paul F et al.Investigative ophthalmology & visual science. 2002, Vol 43, Num 11, pp 3583-3589, issn 0146-0404, 7 p.Article

Adeno-Associated Virus-Mediated Rhodopsin Replacement Provides Therapeutic Benefit in Mice with a Targeted Disruption of the Rhodopsin GenePALFI, Arpad; MILLINGTON-WARD, Sophia; FARRAR, G. Jane et al.Human gene therapy. 2010, Vol 21, Num 3, pp 311-323, issn 1043-0342, 13 p.Article

A transgenic mouse model for gene therapy of rhodopsin-linked Retinitis PigmentosaO'REILLY, Mary; MILLINGTON-WARD, Sophia; PALFI, Arpad et al.Vision research (Oxford). 2008, Vol 48, Num 3, pp 386-391, issn 0042-6989, 6 p.Article

Ribozyme-based therapeutic approaches for autosomal dominant retinitis pigmentosaO'NEILL, Brian; MILLINGTON-WARD, Sophia; O'REILLY, Mary et al.Investigative ophthalmology & visual science. 2000, Vol 41, Num 10, pp 2863-2869, issn 0146-0404Article

C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosaHUMPHRIES, Marian M; KENNA, Paul F; CAMPBELL, Matthew et al.European journal of human genetics. 2012, Vol 20, Num 1, pp 64-68, issn 1018-4813, 5 p.Article

Study of Gene-Targeted Mouse Models of Splicing Factor Gene Prpf31 Implicated in Human Autosomal Dominant Retinitis Pigmentosa (RP)BUJAKOWSKA, Kinga; MAUBARET, Cecilia; PAQUET-DURAND, François et al.Investigative ophthalmology & visual science. 2009, Vol 50, Num 12, pp 5927-5933, issn 0146-0404, 7 p.Article

Apoptotic photoreceptor death in the rhodopsin knockout mouse in the presence and absence of c-fosHOBSON, Audrey H; DONOVAN, Maryanne; HUMPHRIES, Marian M et al.Experimental eye research. 2000, Vol 71, Num 3, pp 247-254, issn 0014-4835Article

On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosaAHERNE, Aileen; KENNAN, Avril; JING JIN GU et al.Human molecular genetics (Print). 2004, Vol 13, Num 6, pp 641-650, issn 0964-6906, 10 p.Article

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvementBOWNE, Sara J; HUMPHRIES, Marian M; FULTON, Robert S et al.European journal of human genetics. 2011, Vol 19, Num 10, pp 1074-1081, issn 1018-4813, 8 p.Article

Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho^-/- miceKENNAN, Avril; AHERNE, Aileen; KENNA, Paul F et al.Human molecular genetics (Print). 2002, Vol 11, Num 5, pp 547-557, issn 0964-6906Article

Murine model of autosomal dominant retinitis pigmentosa generated by targeted deletion at codon 307 of the rds-peripherin geneMCNALLY, Niamh; KENNA, Paul F; HUMPHRIES, Peter et al.Human molecular genetics (Print). 2002, Vol 11, Num 9, pp 1005-1016, issn 0964-6906Article

Validation in mesenchymal progenitor cells of a mutation-independent ex vivo approach to gene therapy for osteogenesis imperfectaMILLINGTON-WARD, Sophia; ALLERS, Carolina; TUOHY, Gearoid et al.Human molecular genetics (Print). 2002, Vol 11, Num 19, pp 2201-2206, issn 0964-6906Article

Efficacy of Codelivery of Dual AAV2/5 Vectors in the Murine Retina and HippocampusPALFI, Arpad; CHADDERTON, Naomi; MCKEE, Alex G et al.Human gene therapy. 2012, Vol 23, Num 8, pp 847-858, issn 1043-0342, 12 p.Article

Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90)TAM, Lawrence C. S; KIANG, Anna-Sophia; CAMPBELL, Matthew et al.Human molecular genetics (Print). 2010, Vol 19, Num 22, pp 4421-4436, issn 0964-6906, 16 p.Article

Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10)TAM, Lawrence C. S; KIANG, Anna-Sophia; REYNOLDS, Alison et al.Human molecular genetics (Print). 2008, Vol 17, Num 14, pp 2084-2100, issn 0964-6906, 17 p.Article

RNA interference-mediated suppression and replacement of human rhodopsin in vivoO'REILLY, Mary; PAIFI, Arpad; MCNALLY, Niamh et al.American journal of human genetics. 2007, Vol 81, Num 1, pp 127-135, issn 0002-9297, 9 p.Article

Rnai of COL1A1 in mesenchymal progenitor cellsMILLINGTON-WARD, Sophia; MCMAHON, Helena P; ALLEN, Danny et al.European journal of human genetics. 2004, Vol 12, Num 10, pp 864-866, issn 1018-4813, 3 p.Article