Suppression of renin-angiotensin system attenuates hepatocarcinogenesis Via angiogenesis inhibition in ratsYOSHIJI, Hitoshi; NOGUCHI, Ryuichi; FUKUI, Hiroshi et al.Anticancer research. 2005, Vol 25, Num 5, pp 3335-3340, issn 0250-7005, 6 p.Article

Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in ratsKITADE, Mitsuteru; YOSHIJI, Hitoshi; YAMAZAKI, Masaharu et al.Hepatology (Baltimore, Md.). 2006, Vol 44, Num 4, pp 983-991, issn 0270-9139, 9 p.Article

Combination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma development and angiogenesis in miceYOSHIJI, Hitoshi; YOSHII, Junichi; KURIYAMA, Shigeki et al.Oncology reports. 2005, Vol 14, Num 1, pp 213-218, issn 1021-335X, 6 p.Article

Renin-Angiotensin System Inhibitors as Therapeutic Alternatives in the Treatment of Chronic Liver DiseasesYOSHIJI, Hitoshi; NOGUCHI, Ryuichi; IKENAKA, Yasuhide et al.Current medicinal chemistry. 2007, Vol 14, Num 26, pp 2749-2754, issn 0929-8673, 6 p.Article

Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activitiesNOGUCHI, Ryuichi; YOSHIJI, Hitoshi; KAWARATANI, Hideto et al.Oncology reports. 2009, Vol 22, Num 2, pp 355-360, issn 1021-335X, 6 p.Article

Salvage effect of the vascular endothelial growth factor on chemically induced acute severe liver injury in ratsNAMISAKI, Tadashi; YOSHIJI, Hitoshi; ASADA, Kiyoshi et al.Journal of hepatology. 2006, Vol 44, Num 3, pp 568-575, issn 0168-8278, 8 p.Article

Different cascades in the signaling pathway of two vascular endothelial growth factor (VEGF) receptors for the VEGF-mediated murine hepatocellular carcinoma developmentYOSHIJI, Hitoshi; NOGUCHI, Ryuichi; FUKUI, Hiroshi et al.Oncology reports. 2005, Vol 13, Num 5, pp 853-857, issn 1021-335X, 5 p.Article

Imatinib mesylate (STI-571) attenuates liver fibrosis development in ratsYOSHIJI, Hitoshi; NOGUCHI, Ryuichi; KURIYAMA, Shigeki et al.American journal of physiology. Gastrointestinal and liver physiology. 2005, Vol 51, Num 5, pp G907-G913, issn 0193-1857Article

Hepatocyte Growth Factor/c-Met Signaling Is Required for Stem-Cell-Mediated Liver Regeneration in MiceISHIKAWA, Tsuyoshi; FACTOR, Valentina M; MARQUARDT, Jens U et al.Hepatology (Baltimore, Md.). 2012, Vol 55, Num 4, pp 1215-1226, issn 0270-9139, 12 p.Article

Definition of Ubiquitination Modulator COP1 as a Novel Therapeutic Target in Human Hepatocellular CarcinomaLEE, Yun-Han; ANDERSEN, Jesper B; HYUN GOO WOO et al.Cancer research (Chicago, Ill.). 2010, Vol 70, Num 21, pp 8264-8269, issn 0008-5472, 6 p.Article

Combination of vitamin K₂ and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinomaYOSHIJI, Hitoshi; NOGUCHI, Ryuichi; YOSHIDA, Motoyuki et al.Journal of hepatology. 2009, Vol 51, Num 2, pp 315-321, issn 0168-8278, 7 p.Article

Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in miceYOSHIJI, Hitoshi; NOGUCHI, Ryuichi; KURIYAMA, Shigeki et al.Oncology reports. 2005, Vol 13, Num 3, pp 491-495, issn 1021-335X, 5 p.Article

Combination of interferon-β and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and AngiogenesisNOGUCHI, Ryuichi; YOSHIJI, Hitoshi; TSUJINOUE, Hirohisa et al.Clinical cancer research. 2003, Vol 9, Num 16, pp 6038-6045, issn 1078-0432, 8 p., 1Article

Antitumor Effects in Hepatocarcinoma of Isoform-Selective Inhibition of HDAC2LEE, Yun-Han; DAEKWAN SEO; CONNER, Elizabeth A et al.Cancer research (Chicago, Ill.). 2014, Vol 74, Num 17, pp 4752-4761, issn 0008-5472, 10 p.Article

Human Hepatic Cancer Stem Cells Are Characterized by Common Stemness Traits and Diverse Oncogenic PathwaysMARQUARDT, Jens U; RAGGI, Chiara; CONNER, Elizabeth A et al.Hepatology (Baltimore, Md.). 2011, Vol 54, Num 3, pp 1031-1042, issn 0270-9139, 12 p.Article

Synergistic inhibition of hepatocellular carcinoma growth and hepatocarcinogenesis by combination of 5-fluorouracil and angiotensin-converting enzyme inhibitor via anti-angiogenic activitiesYANASE, Koji; YOSHIJI, Hitoshi; TSUJIMOTO, Tatsuhiro et al.Oncology reports. 2007, Vol 17, Num 2, pp 441-446, issn 1021-335X, 6 p.Article

Combination of vitamin K₂ and the angiotensin-converting enzyme inhibitor, perindopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppressionYOSHIJI, Hitoshi; KURIYAMA, Shigeki; FUKUI, Hiroshi et al.Journal of hepatology. 2005, Vol 42, Num 5, pp 687-693, issn 0168-8278, 7 p.Article

Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in ratsKAJI, Kosuke; YOSHIJI, Hitoshi; TSUJIMOTO, Tatsuhiro et al.American journal of physiology. Gastrointestinal and liver physiology. 2011, Vol 63, Num 6, issn 0193-1857, G1094-G1104Article

Different tumoricidal effects of interferon subclasses and p53 status on hepatocellular carcinoma development and neovascularizationNOGUCHI, Ryuichi; YOSHIJI, Hitoshi; AKAHANE, Takemi et al.International journal of oncology. 2008, Vol 32, Num 1, pp 193-199, issn 1019-6439, 7 p.Article

Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K₂ and angiotensin-converting enzyme inhibitor via anti-angiogenic activitiesYOSHIJI, Hitoshi; KURIYAMA, Shigeki; ASADA, Kiyoshi et al.Oncology reports. 2006, Vol 15, Num 1, pp 155-159, issn 1021-335X, 5 p.Article

Intrahepatic cholangiocarcinoma associated with central calcification and arterio-portal shuntKITADE, Mitsuteru; YOSHIJI, Hitoshi; UEMURA, Masahito et al.Internal medicine (Tokyo. 1992). 2005, Vol 44, Num 8, pp 825-828, issn 0918-2918, 4 p.Article

Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in miceYOSHIJI, Hitoshi; KURIYAMA, Shigeki; YAMAZAKI, Masaharu et al.Hepatology (Baltimore, Md.). 2004, Vol 39, Num 6, pp 1517-1524, issn 0270-9139, 8 p.Article

Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma developmentYOSHIJI, Hitoshi; KURIYAMA, Shigeki; MASAKI, Tsutomu et al.Journal of hepatology. 2004, Vol 41, Num 1, pp 97-103, issn 0168-8278, 7 p.Article