Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumorsADAMS, Val R; LEGGAS, Markos.Clinical therapeutics. 2007, Vol 29, Num 7, pp 1338-1353, issn 0149-2918, 16 p.Article

Pharmacokinetics of high-dose simvastatin in refractory and relapsed chronic lymphocytic leukemia patientsAHMED, Tamer A; HAYSLIP, John; LEGGAS, Markos et al.Cancer chemotherapy and pharmacology. 2013, Vol 72, Num 6, pp 1369-1374, issn 0344-5704, 6 p.Article

Metabolic Pathways of the Camptothecin Analog AR-67HORN, Jamie; MILEWSKA, Marta; ARNOLD, Susanne M et al.Drug metabolism and disposition. 2011, Vol 39, Num 4, pp 683-692, issn 0090-9556, 10 p.Article

Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibitionDAILY, Abigail; MONKS, Noel R; LEGGAS, Markos et al.Toxicon (Oxford). 2010, Vol 55, Num 4, pp 827-837, issn 0041-0101, 11 p.Article

Pharmacokinetic Modeling to Assess Factors Affecting the Oral Bioavailability of the Lactone and Carboxylate Forms of the Lipophilic Camptothecin Analogue AR-67 in RatsADANE, Eyob D; ZHIWEI LIU; XIANG, Tian-Xiang et al.Pharmaceutical research. 2012, Vol 29, Num 7, pp 1722-1736, issn 0724-8741, 15 p.Article

Factors Affecting the In Vivo Lactone Stability and Systemic Clearance of the Lipophilic Camptothecin Analogue AR-67ADANE, Eyob D; ZHIWEI LIU; XIANG, Tian-Xiang et al.Pharmaceutical research. 2010, Vol 27, Num 7, pp 1416-1425, issn 0724-8741, 10 p.Article

Microbore HPLC method with online microdialysis for measurement of topotecan lactone and carboxylate in murine CSFLEGGAS, Markos; YANLI ZHUANG; WELDEN, Jonathan et al.Journal of pharmaceutical sciences. 2004, Vol 93, Num 9, pp 2284-2295, issn 0022-3549, 12 p.Article

0N-(4-[2-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine Carboxamide (GF120918) As a Chemical ATP-Binding Cassette Transporter Family G Member 2 (Abcg2) Knockout Model to Study Nitrofurantoin Transfer into MilkLIPENG WANG; LEGGAS, Markos; GOSWAMI, Mamta et al.Drug metabolism and disposition. 2008, Vol 36, Num 12, pp 2591-2596, issn 0090-9556, 6 p.Article

Protracted dosing of the lipophilic camptothecin analogue AR-67 in non-small cell lung cancer xenografts and humansTSAKALOZOU, Eleftheria; ADANE, Eyob D; YALI LIANG et al.Cancer chemotherapy and pharmacology. 2014, Vol 74, Num 1, pp 45-54, issn 0344-5704, 10 p.Article

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasmaHORN, Jamie; JORDAN, Sherri L; LIN SONG et al.Journal of chromatography. B. 2006, Vol 844, Num 1, pp 15-22, issn 1570-0232, 8 p.Article

Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in ratsANDERSON, Bradley D; MAY, Melissa J; JORDAN, Sherri et al.Drug metabolism and disposition. 2006, Vol 34, Num 4, pp 653-659, issn 0090-9556, 7 p.Article

Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivoLEGGAS, Markos; PANETTA, John C; YANLI ZHUANG et al.Cancer research (Baltimore). 2006, Vol 66, Num 9, pp 4802-4807, issn 0008-5472, 6 p.Article

Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distributionTAKENAKA, Kazumasa; MORGAN, Jessica A; SCHEFFER, George L et al.Cancer research (Baltimore). 2007, Vol 67, Num 14, pp 6965-6972, issn 0008-5472, 8 p.Article

Relation between irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenograftsLEGGAS, Markos; STEWART, Clinton F; WOO, Michael H et al.Clinical cancer research. 2002, Vol 8, Num 9, pp 3000-3007, issn 1078-0432, 8 p.Article

Intensive anti-inflammatory therapy with dexamethasone in patients with non-small cell lung cancer : effect on chemotherapy toxicity and efficacyLEGGAS, Markos; KUO, Kuei-Ling; ROBERT, Francisco et al.Cancer chemotherapy and pharmacology. 2009, Vol 63, Num 4, pp 731-743, issn 0344-5704, 13 p.Article

Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in miceSTEWART, Clinton F; LEGGAS, Markos; HARWOOD, Franklin C et al.Cancer research (Baltimore). 2004, Vol 64, Num 20, pp 7491-7499, issn 0008-5472, 9 p.Article

Immunohistochemical detection of multidrug-resistant protein expression in retinoblastoma treated by primary enucleationWILSON, Matthew W; FRAGA, Charles H; FULLER, Christine E et al.Investigative ophthalmology & visual science. 2006, Vol 47, Num 4, pp 1269-1273, issn 0146-0404, 5 p.Article