The histamine H₃-receptor: a target for developing new drugsLEURS, R; TIMMERMAN, H.Progress in drug research. 1992, Vol 39, pp 127-165, issn 0071-786XArticle

Short-term desensitization of the histamine H₁ receptor in human HeLa cells : involvement of protein kinase C dependent and independent pathwaysSMIT, M. J; BLOEMERS, S. M; LEURS, R et al.British journal of pharmacology. 1992, Vol 107, Num 2, pp 448-455, issn 0007-1188Article

Identification of β₂-adrenoceptors on Guinea pig alveolar macrophages using (-)-3[¹²⁵I]iodocyanopindololLEURS, R; BEUSENBERG, F. D; BAST, A et al.Inflammation. 1990, Vol 14, Num 4, pp 421-426, issn 0360-3997, 6 p.Article

Mineral dust exposure and free radical-mediated lung damageDOELMAN, C. J. A; LEURS, R; OOSTEROM, W. C et al.Experimental lung research. 1990, Vol 16, Num 1, pp 41-55, issn 0190-2148, 15 p.Article

H₁-antihistamines: Inverse agonism, anti-inflammatory actions and cardiac effectsLEURS, R; CHURCH, M. K; TAGLIALATELA, M et al.Clinical and experimental allergy (Print). 2002, Vol 32, Num 4, pp 489-498, issn 0954-7894Article

Histamine receptors : subclasses and specific ligandsHAAKSMA, E. E. J; LEURS, R; TIMMERMAN, H et al.Pharmacology & therapeutics (Oxford). 1990, Vol 47, Num 1, pp 73-104, issn 0163-7258, 32 p.Article

The medicinal chemistry and therapeutic potentials of ligands of the histamine H₃ receptorLEURS, R; VOLLINGA, R. C; TIMMERMAN, H et al.Progress in drug research. 1995, Vol 45, pp 107-165, issn 0071-786XArticle

Ebselen inhibits contractile responses of guinea-pig parenchymal lung stripsLEURS, R; BAST, A; TIMMERMAN, H et al.European journal of pharmacology. 1990, Vol 179, Num 1-2, pp 193-199, issn 0014-2999Article

Interaction of nefopam and orphenadrine with the cytochrome P-450 and the glutathione system in rat liverLEURS, R; DONNELL, D; TIMMERMAN, H et al.Journal of pharmacy and pharmacology. 1989, Vol 41, Num 6, pp 388-393, issn 0022-3573Article

Fluoride is a contractile agent of guinea pig airway smooth muscleLEURS, R; BAST, A; TIMMERMAN, H et al.General pharmacology. 1991, Vol 22, Num 4, pp 631-636, issn 0306-3623, 6 p.Article

High affinity, saturable [³H]mepyramine binding sites on rat liver plasma membrane do not represent histamine H₁-receptors: a warningLEURS, R; BAST, A; TIMMERMAN, H et al.Biochemical pharmacology. 1989, Vol 38, Num 13, pp 2175-2180, issn 0006-2952Article

Histaminergic agonists and antagonists recent developmentsLEURS, R; VAN DER GOOT, H; TIMMERMAN, H et al.Advances in Drug Research. 1991, Vol 20, pp 217-304, issn 0065-2490, 88 p.Article

Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3SCHOLTEN, D. J; CANALS, M; WIJTMANS, M et al.British journal of pharmacology. 2012, Vol 166, Num 3, pp 898-911, issn 0007-1188, 14 p.Article

Antinociceptive activity of derivatives of improgran and burimamideHOUGH, L. B; NALWALK, J. W; LEURS, R et al.Pharmacology, biochemistry and behavior. 2000, Vol 65, Num 1, pp 61-66, issn 0091-3057Article

Constitutive activity of the histamine H₁ receptor reveals inverse agonism of histamine H₁ receptor antagonistsBAKKER, R. A; WIELAND, K; TIMMERMAN, H et al.European journal of pharmacology. 2000, Vol 387, Num 1, pp R5-R7, issn 0014-2999Article

Platelet adenylyl cyclase activity as a biochemical trait marker for predisposition to alcoholismRATSMA, J. E; GUNNING, W. B; LEURS, R et al.Alcoholism, clinical and experimental research. 1999, Vol 23, Num 4, pp 600-604, issn 0145-6008Article

Inhibition of cortical acetylcholine release and cognitive performance by histamine H₃ receptor activation in ratsBLANDINA, P; GIORGETTI, M; BARTOLINI, L et al.British journal of pharmacology. 1996, Vol 119, Num 8, pp 1656-1664, issn 0007-1188Article

Extracellular ATP elevates cytoplasmatic free Ca²⁺ in HeLA cells by the interaction with a 5'-nucleotide receptorSMIT, M. J; LEURS, R; BLOEMERS, S. M et al.European journal of pharmacology. Molecular pharmacology section. 1993, Vol 247, Num 2, pp 223-226, issn 0922-4106Article

Expression of a cloned rat histamine H₂ receptor mediating inhibition of arachidonate release and activation of cAMP accumulationTRAIFFORT, E; RUAT, M; ARRANG, J.-M et al.Proceedings of the National Academy of Sciences of the United States of America. 1992, Vol 89, Num 7, pp 2649-2653, issn 0027-8424Article

Homologous histamine H₁ receptor desensitization results in reduction of H₁ receptor agonist efficacyLEURS, R; SMIT, M. J; BAST, A et al.European journal of pharmacology. 1991, Vol 196, Num 3, pp 319-322, issn 0014-2999, 4 p.Article

Absence of 5-HT₃ and cholinergic mechanisms in improgan antinociceptionNALWALK, J. W; SVOKOS, K; LEURS, R et al.Pharmacology, biochemistry and behavior. 2005, Vol 80, Num 3, pp 505-510, issn 0091-3057, 6 p.Article

Pharmacological analysis of immepip and imetit homologues. Further evidence for histamine H₃ receptor heterogeneity?ALVES-RODRIGUES, A; LEMSTRA, S; VOLLINGA, R. C et al.Behavioural brain research. 2001, Vol 124, Num 2, pp 121-127, issn 0166-4328Article

Evaluation of [¹⁸F]VUF 5000 as a potential PET ligand for brain imaging of the histamine H₃ receptorWINDHORST, A. D; TIMMERMAN, H; KLOK, R. P et al.Bioorganic & medicinal chemistry. 1999, Vol 7, Num 9, pp 1761-1767, issn 0968-0896Article

Radiosynthesis and biodistribution of ¹²³I-labeled antagonists of the histamine H₃ receptor as potential SPECT ligandsWINDHORST, A. D; TIMMERMAN, H; HERSCHEID, J. D. M et al.Nuclear medicine and biology. 1999, Vol 26, Num 6, pp 651-659, issn 0969-8051Article

The C terminal tail of the histamine H₂ receptor contains positive and negative signals important for signal transduction and receptor Down-regulationSMIT, M. J; TIMMERMAN, H; BLAUW, J et al.Journal of neurochemistry. 1996, Vol 67, Num 5, pp 1791-1800, issn 0022-3042Article