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Cyclin A downregulation and p21^cip1 upregulation correlate with GATA-6-induced growth arrest in glomerular mesangial cellsNAGATA, Daisuke; SUZUKI, Etsu; HIRATA, Yasunobu et al.Circulation research. 2000, Vol 87, Num 8, pp 699-704, issn 0009-7330Article

Therapeutic effects of angiotensin II type 1 receptor blocker at an advanced stage of hypertensive diastolic heart failureNISHIO, Mayu; SAKATA, Yasushi; MANO, Toshiaki et al.Journal of hypertension. 2007, Vol 25, Num 2, pp 455-461, issn 0263-6352, 7 p.Article

Angiotensin II type 1 and endothelin type A receptor antagonists modulate the extracellular matrix regulatory system differently in diastolic heart failureYOSHIDA, Junichi; YAMAMOTO, Kazuhiro; MANO, Toshiaki et al.Journal of hypertension. 2003, Vol 21, Num 2, pp 437-444, issn 0263-6352, 8 p.Article

Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure : beneficial effects of mineralocorticoid receptor blockerOHTANI, Tomohito; OHTA, Miho; MASUYAMA, Tohru et al.American journal of physiology. Regulatory, integrative and comparative physiology. 2007, Vol 61, Num 2, issn 0363-6119, R946-R954Article

Involvement of nuclear factor-κb and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophyHIROTANI, Shinichi; OTSU, Kinya; TADA, Michihiko et al.Circulation (New York, N.Y.). 2002, Vol 105, Num 4, pp 509-515, issn 0009-7322Article

AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failureYOSHIDA, Junichi; YAMAMOTO, Kazuhiro; MANO, Toshiaki et al.Hypertension (Dallas, Tex. 1979). 2004, Vol 43, Num 3, pp 686-691, issn 0194-911X, 6 p.Article

N-Methylethanolamine attenuates cardiac fibrosis and improves diastolic function: inhibition of phospholipase D as a possible mechanismYAMAMOTO, Kazuhiro; TAKAHASHI, Yoshito; MASUYAMA, Tohru et al.European heart journal. 2004, Vol 25, Num 14, pp 1221-1229, issn 0195-668X, 9 p.Article

Differential activation of matrix metalloproteinases in heart failure with and without ventricular dilatationNISHIKAWA, Nagahiro; YAMAMOTO, Kazuhiro; SAKATA, Yasushi et al.Cardiovascular research. 2003, Vol 57, Num 3, pp 766-774, issn 0008-6363, 9 p.Article

Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expressionPERLMAN, Harris; HONGTAO LIU; POPE, Richard M et al.Journal of rheumatology. 2002, Vol 29, Num 8, pp 1593-1600, issn 0315-162XArticle

Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heartYAMAMOTO, Kazuhiro; MASUYAM, Tohru; SUZUKI, Keiichiro et al.Cardiovascular research. 2002, Vol 55, Num 1, pp 76-82, issn 0008-6363Article

Ace inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failureYAMAMOTO, Kazuhiro; MANO, Toshiaki; YOSHIDA, Junichi et al.Journal of hypertension. 2005, Vol 23, Num 2, pp 393-400, issn 0263-6352, 8 p.Article

Activation of matrix metalloproteinases precedes left ventricular remodeling in hypertensive heart failure rats: Its inhibition as a primary effect of angiotensin-converting enzyme inhibitorSAKATA, Yasushi; YAMAMOTO, Kazuhiro; MANO, Toshiaki et al.Circulation (New York, N.Y.). 2004, Vol 109, Num 17, pp 2143-2149, issn 0009-7322, 7 p.Article

Prevention of diastolic heart failure by endothelin type A receptor antagonist through inhibition of ventricular structural remodeling in hypertensive heartYAMAMOTO, Kazuhiro; MASUYAMA, Tohru; SAKATA, Yasushi et al.Journal of hypertension. 2002, Vol 20, Num 4, pp 753-761, issn 0263-6352Article

Long-term administration of amlodipine prevents decompensation to diastolic heart failure in hypertensive ratsNISHIKAWA, Nagahiro; MASUYAMA, Tohru; YAMAMOTO, Kazuhiro et al.Journal of the American College of Cardiology. 2001, Vol 38, Num 5, pp 1539-1545, issn 0735-1097Article

Ventricular production of natriuretic peptides and ventricular structural remodeling in hypertensive heart failureSAKATA, Yasushi; YAMAMOTO, Kazuhiro; MASUYAMA, Tohru et al.Journal of hypertension. 2001, Vol 19, Num 10, pp 1905-1912, issn 0263-6352Article

Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failureOHTANI, Tomohito; MANO, Toshiaki; YAMAMOTO, Kazuhiro et al.Journal of hypertension. 2009, Vol 27, Num 5, pp 1074-1083, issn 0263-6352, 10 p.Article

Different effects of long- and short-acting loop diuretics on survival rate in Dahl high-salt heart failure model ratsYOSHIDA, Junichi; YAMAMOTO, Kazuhiro; MANO, Toshiaki et al.Cardiovascular research. 2005, Vol 68, Num 1, pp 118-127, issn 0008-6363, 10 p.Article

Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophyYAMAGUCHI, Hitoshi; YOSHIDA, Junichi; YAMAMOTO, Kazuhiro et al.Journal of the American College of Cardiology. 2004, Vol 43, Num 1, pp 55-60, issn 0735-1097, 6 p.Article

Temocapril prevents transition to diastolic heart failure in rats even if initiated after appearance of LV hypertrophy and diastolic dysfunctionSAKATA, Yasushi; YAMAMOTO, Kazuhiro; MANO, Toshiaki et al.Cardiovascular research. 2003, Vol 57, Num 3, pp 757-765, issn 0008-6363, 9 p.Article

Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca²⁺ regulatory proteins and extracellular matrixSAKATA, Yasushi; YAMAMOTO, Kazuhiro; MIWA, Takeshi et al.Journal of hypertension. 2003, Vol 21, Num 9, pp 1737-1745, issn 0263-6352, 9 p.Article

Renin angiotensin system-dependent hypertrophy as a contributor to heart failure in hypertensive rats : Different characteristics from renin angiotensin system-independent hypertrophySAKATA, Yasushi; MASUYAMA, Tohru; YAMAMOTO, Kazuhiro et al.Journal of the American College of Cardiology. 2001, Vol 37, Num 1, pp 293-299, issn 0735-1097Conference Paper

Local neurohumoral regulation in the transition to isolated diastolic heart failure in hypertensive heart disease : absence of AT1 receptor downregulation and overdrive' of the endothelin systemYAMAMOTO, Kazuhiro; MASUYAMA, Tohru; SAKATA, Yasushi et al.Cardiovascular research. 2000, Vol 46, Num 3, pp 421-432, issn 0008-6363Article