Interaction between DNA gyrase and quinolones: Effects of alanine mutations at GyrA subunit residues Ser⁸³ and Asp⁸⁷BARNARD, Faye M; MAXWELL, Anthony.Antimicrobial agents and chemotherapy. 2001, Vol 45, Num 7, pp 1994-2000, issn 0066-4804Article

Quinolone-binding pocket of DNA gyrase: Role of GyrBHEDDLE, Jonathan; MAXWELL, Anthony.Antimicrobial agents and chemotherapy. 2002, Vol 46, Num 6, pp 1805-1815, issn 0066-4804Article

Quinolone-DNA interaction: Sequence-dependent binding to single-stranded DNA reflects the interaction within the gyrase-DNA complexNOBLE, Christian G; BARNARD, Faye M; MAXWELL, Anthony et al.Antimicrobial agents and chemotherapy. 2003, Vol 47, Num 3, pp 854-862, issn 0066-4804, 9 p.Article

Exploiting bacterial DNA gyrase as a drug target: current state and perspectivesCOLLIN, Frédéric; KARKARE, Shantanu; MAXWELL, Anthony et al.Applied microbiology and biotechnology. 2011, Vol 92, Num 3, pp 479-497, issn 0175-7598, 19 p.Article

DNA Gyrase from the Albicidin Producer Xanthomonas albilineans Has Multiple-Antibiotic-Resistance and Unusual Enzymatic PropertiesHASHIMI, Saeed M; GUOZHONG HUANG; MAXWELL, Anthony et al.Antimicrobial agents and chemotherapy. 2008, Vol 52, Num 4, pp 1382-1390, issn 0066-4804, 9 p.Article

Dissection of the bacteriophage mu strong gyrase site (SGS) : Significance of the SGS right arm in mu biology and DNA gyrase mechanismORAM, Mark; TRAVERS, Andrew A; HOWELLS, Alison J et al.Journal of bacteriology. 2005, Vol 188, Num 2, pp 619-632, issn 0021-9193, 14 p.Article

Biological Activities of Novel Gyrase Inhibitors of the Aminocoumarin ClassANDERLE, Christine; STIEGER, Martin; BURRELL, Matthew et al.Antimicrobial agents and chemotherapy. 2008, Vol 52, Num 6, pp 1982-1990, issn 0066-4804, 9 p.Article

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesisFLATMAN, Ruth H; EUSTAQUIO, Alessandra; LI, Shu-Ming et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 4, pp 1136-1142, issn 0066-4804, 7 p.Article

Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone in Streptomyces antibioticusLE, Tung B. K; FIEDLER, Hans-Peter; DEN HENGST, Chris D et al.Molecular microbiology (Print). 2009, Vol 72, Num 6, pp 1462-1474, issn 0950-382X, 13 p.Article

Chimeric VEGFRs are activated by a small-molecule dimerizer and mediate downstream signalling cascades in endothelial cellsKNIGHT, Emma L; WARNER, Andrea J; MAXWELL, Anthony et al.Oncogene (Basingstoke). 2000, Vol 19, Num 47, pp 5398-5405, issn 0950-9232Article

Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibioticsALT, Silke; MITCHENALL, Lesley A; MAXWELL, Anthony et al.Journal of antimicrobial chemotherapy (Print). 2011, Vol 66, Num 9, pp 2061-2069, issn 0305-7453, 9 p.Article

Structural and Biochemical Analysis of the Pentapeptide Repeat Protein EfsQnr, a Potent DNA Gyrase InhibitorHEGDE, Subray S; VETTING, Matthew W; MITCHENALL, Lesley A et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 1, pp 110-117, issn 0066-4804, 8 p.Article

A mutation in Escherichia coli DNA gyrase conferring quinolone resistance results in sensitivity to drugs targeting eukaryotic topoisomerase IIGRUGER, Thomas; NITISS, John L; MAXWELL, Anthony et al.Antimicrobial agents and chemotherapy. 2004, Vol 48, Num 12, pp 4495-4504, issn 0066-4804, 10 p.Article

Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breastTHOMAS, Jeremy; HANBY, Andrew; THOMPSON, Alastair et al.European journal of cancer (1990). 2014, Vol 50, Num 11, pp 1880-1890, issn 0959-8049, 11 p.Article

Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombinationSTACEY, Nicola J; KUROMORI, Takashi; AZUMI, Yoshitaka et al.Plant journal. 2006, Vol 48, Num 2, pp 206-216, issn 0960-7412, 11 p.Article

A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNAHEGDE, Subray S; VETTING, Matthew W; RODERICK, Steven L et al.Science (Washington, D.C.). 2005, Vol 308, Num 5727, pp 1480-1483, issn 0036-8075, 4 p.Article

Simocyclinone D8, an inhibitor of DNA gyrase with a novel mode of actionFLATMAN, Ruth H; HOWELLS, Alison J; HEIDE, Lutz et al.Antimicrobial agents and chemotherapy. 2005, Vol 49, Num 3, pp 1093-1100, issn 0066-4804, 8 p.Article

A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA GyraseEDWARDS, Marcus J; FLATMAN, Ruth H; MAXWELL, Anthony et al.Science (Washington, D.C.). 2009, Vol 326, Num 5958, pp 1415-1418, issn 0036-8075, 4 p.Article

The phytotoxin albicidin is a novel inhibitor of DNA gyraseHASHIMI, Saeed M; WALL, Melisa K; SMITH, Andrew B et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 1, pp 181-187, issn 0066-4804, 7 p.Article

Novobiocin : Redesigning a DNA gyrase inhibitor for selective inhibition of Hsp90BURLISON, Joseph A; NECKERS, Len; SMITH, Andrew B et al.Journal of the American Chemical Society. 2006, Vol 128, Num 48, pp 15529-15536, issn 0002-7863, 8 p.Article

Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone actionSTRUMBERG, Dirk; NITISS, John L; JIAOWANG DONG et al.Antimicrobial agents and chemotherapy. 2002, Vol 46, Num 9, pp 2735-2746, issn 0066-4804Article

Primary and metastatic lobular carcinoma of the breastHARAKE, Marie D. J; MAXWELL, Anthony J; SUKUMAR, Sathi A et al.Clinical radiology. 2001, Vol 56, Num 8, pp 621-630, issn 0009-9260Article