Stereoselective olefin formation from the dehydration of 1-(p-alkoxyphenyl)-1,2-diphenylbutan-1-ols: application to the synthesis of tamoxifen = Obtention de cisdiphényl-1,2 méthoxy-4'(chloro-2″éthyl-4') butènes-1 et du tamoxifèneMCCAGUE, R.Journal of the Chemical Society. Perkin transactions. I. 1987, Num 5, pp 1011-1015, issn 0300-922XArticle

A route to conformationally restricted antioestrogens by coupling of a vinyl triflate with an aryl zinc chlorideMCCAGUE, R.Tetrahedron letters. 1987, Vol 28, Num 6, pp 701-702, issn 0040-4039Article

Crystallisation and industrial chiral synthesisMCCAGUE, R.Manufacturing chemist (London. 1981). 1998, Vol 69, Num 3, pp 13-17, issn 0262-4230, 4 p.Article

The use of the perfluorotolyl protecting group in the synthesis of pure Z- and E-isomers of 4-hydroxytamoxifen {1-[4-(2-dimethylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbut-1-ene}MCCAGUE, R.Journal of chemical research. Synopses (Print). 1986, Num 2, pp 58-59, issn 0308-2342Article

Enantiomeric purity with conglomeratesMCCAGUE, R.Manufacturing chemist (London. 1981). 1998, Vol 69, Num 4, pp 22-23, issn 0262-4230Article

PHENOL-KETO TAUTOMERISM IN TRICYCLIC (10) ANNULENES; PREPARATION AND PROPERTIES OF 7B-METHYL-2A, 7B-DIHYDROCYCLOPENT (CD) INDEN-2-(2H)-ONEMCCAGUE R; MOODY CJ; REES CW et al.1982; J. CHEM. SOC., CHEM. COMMUN.; ISSN 0022-4936; GBR; DA. 1982; NO 11; PP. 622-624; BIBL. 7 REF.Article

ELECTROPHILIC SUBSTITUTION IN A TRICYCLIC (10) ANNULENEMCCAGUE R; MOODY CJ; REES CW et al.1982; J. CHEM. SOC., CHEM. COMMUN.; ISSN 0022-4936; GBR; DA. 1982; NO 9; PP. 497-499; BIBL. 8 REF.Article

Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen)MCCAGUE, R; LECLERCQ, G.Journal of medicinal chemistry (Print). 1987, Vol 30, Num 10, pp 1761-1767, issn 0022-2623Article

The selective protection of the 3-ketone functions of steroids as heptafluoro-p-tolyl enol ethersJARMAN, M; MCCAGUE, R.Journal of the Chemical Society. Perkin transactions. I. 1987, Num 5, pp 1129-1133, issn 0300-922XArticle

Coupling of low-order organocopper complexes with organoiron cations ; synthesis of tamandron, a novel potentially antiandrogenic analogue of tamoxifenPOTTER, G. A; MCCAGUE, R.Journal of the Chemical Society. Chemical communications. 1992, Num 8, pp 635-637, issn 0022-4936Article

Aspects of metabolism of tamoxifen by rat liver microsomes: identification of a new metabolite: E-1-[4-(2-dimethylaminoethoxy)-phenyl]-1, 2-diphenyl-1-buten-3-ol N-oxideMCCAGUE, R; SEAGO, A.Biochemical pharmacology. 1986, Vol 35, Num 5, pp 827-834, issn 0006-2952Article

Synthetic methods for enantiomers of drugsMCCAGUE, R; CASY, G.Progress in medicinal chemistry. 1997, Vol 34, pp 203-261, issn 0079-6468Article

Heptafluoro-p-tolyl as a selective protecting group for the enone function of androst-4-ene-3,17-dione: application to the preparation of deuterium-labelled testosteroneJARMAN, M; MCCAGUE, R.Journal of the Chemical Society. Chemical communications. 1986, Num 8, pp 635-636, issn 0022-4936Article

Octafluorotoluene as a reagent for the selective protection of alcoholic and phenolic functions: synthesis and cleavage of perfluorotolyl and other perfluoroaryl ethers of steroids and other model compoundsJARMAN, M; MCCAGUE, R.Journal of chemical research. Synopses (Print). 1985, Num 4, pp 114-115, issn 0308-2342Article

Heptafluoro-p-tolyl and tetrafluoro-4-pyridyl as novel and selective protecting groups for phenolic and alcoholic functions: synthesis and cleavage of perfluoroaryl ethers of steroidsJARMAN, M; MCCAGUE, R.Journal of the Chemical Society. Chemical communications. 1984, Num 2, pp 125-127, issn 0022-4936Article

Iron-mediated synthesis of homochiral 4-methylcyclohexenone derivatives from p-menthoxytoluenePOTTER, G. A; MCCAGUE, R.Journal of the Chemical Society. Chemical communications. 1990, Num 17, pp 1172-1174, issn 0022-4936, 3 p.Article

highly stereoselective access to an (E)-vinyl bromide from an rayl ketone leads to short syntheses of (Z)-tamoxifen and important substitued derivativesPOTTER, G. A; MCCAGUE, R.Journal of organic chemistry. 1990, Vol 55, Num 25, pp 6184-6187, issn 0022-3263, 4 p.Article

Synthesis of 4-stannylated tamoxifen analogues ; useful precursors to radiolabelled idoxifene and aziridinyl 4-iodotamoxifenMCCAGUE, R; POTTER, G. A.Journal of labelled compounds & radiopharmaceuticals. 1994, Vol 34, Num 3, pp 297-302, issn 0362-4803Article

Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (Rogletimide) and discovery of potent 5-alkyl derivativesMCCAGUE, R; ROWLANDS, M. G.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 20, pp 3699-3704, issn 0022-2623Article

The use of octafluorotoluene and pentafluoropyridine in the synthesis of pure Z- and E-isomers of derivatives of tamoxifen {1,2-diphenyl-1-[4-(2-dimethylaminoethoxy)-phenyl] but-1-ene}JARMAN, M; MCCAGUE, R.Journal of chemical research. Synopses (Print). 1985, Num 4, pp 116-117, issn 0308-2342Article

THE EFFECT OF BENZO-FUSION ON TRICYCLIC (10) ANNULENES: SYNTHESIS, PROPERTIES, AND X-RAY STRUCTURE OF 9C-METHYL-9CH-CYCLOPENTA (JK) FLUORENEMCCAGUE R; MOODY CJ; REES CW et al.1982; J. CHEM. SOC., CHEM. COMMUN.; ISSN 0022-4936; GBR; DA. 1982; NO 18; PP. 1063-1065; BIBL. 6 REF.Article

Enantioselective synthesis of the hydroxy-lactone moiety of mevinic acidsMCCAGUE, R; OLIVO, H. F; ROBERTS, S. M et al.Tetrahedron letters. 1993, Vol 34, Num 23, issn 0040-4039, 3657, 3785-3786[3 p.]Article

Synthesis and estrogen receptor binding of 6,7-dihydro-8-phenyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]5H-benzocycloheptene, a nonisomerizable analogue of tamoxifen. X-ray crystallographic studiesMCCAGUE, R; KURODA, R; LECLERCQ, G et al.Journal of medicinal chemistry (Print). 1986, Vol 29, Num 10, pp 2053-2059, issn 0022-2623Article

A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic oxidative metabolismPOTTER, G. A; MCCAGUE, R; JARMAN, M et al.Carcinogenesis (New York. Print). 1994, Vol 15, Num 3, pp 439-442, issn 0143-3334Article

Tricyclic [10]annulenes. II: Synthesis of 7b-methyl-7bH-cyclopent[cd]indeneMCCAGUE, R; MOODY, C. J; REES, C. W et al.Journal of the Chemical Society. Perkin transactions. I. 1984, Num 2, pp 165-174, issn 0300-922XArticle