RET/PTC activation in papillary thyroid carcinoma : European journal of endocrinology prize lectureSANTORO, Massimo; MELILLO, Rosa Marina; FUSCO, Alfredo et al.European journal of endocrinology. 2006, Vol 155, Num 5, pp 645-653, issn 0804-4643, 9 p.Article

Minireview: RET: Normal and abnormal functionsSANTORO, Massimo; MELILLO, Rosa Marina; CARLOMAGNO, Francesca et al.Endocrinology (Philadelphia). 2004, Vol 145, Num 12, pp 5448-5451, issn 0013-7227, 4 p.Article

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2)CARLOMAGNO, Francesca; VITAGLIANO, Donata; GUIDA, Teresa et al.The Journal of clinical endocrinology and metabolism. 2003, Vol 88, Num 4, pp 1897-1902, issn 0021-972X, 6 p.Article

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteinsIERVOLINO, Angela; IULIANO, Rodolfo; TRAPASSO, Francesco et al.Cancer research (Baltimore). 2006, Vol 66, Num 12, pp 6280-6287, issn 0008-5472, 8 p.Article

The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret : Evidence for a competition between Shc and IRS-1 for the binding to RetMELILLO, Rosa Marina; CARLOMAGNO, Francesca; DE VITA, Gabriella et al.Oncogene (Basingstoke). 2001, Vol 20, Num 2, pp 209-218, issn 0950-9232Article

Increased in vivo phosphorylation of Ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2BSALVATORE, Domenico; MELILLO, Rosa Marina; MONACO, Carmen et al.Cancer research (Baltimore). 2001, Vol 61, Num 4, pp 1426-1431, issn 0008-5472Article

RAI(ShcC/N-Shc)-dependent recruitment of GAB1 to RET oncoproteins potentiates PI3-K signalling in thyroid tumorsDE FALCO, Valentina; GUARINO, Valentina; MALORNI, Luca et al.Oncogene (Basingstoke). 2005, Vol 24, Num 41, pp 6303-6313, issn 0950-9232, 11 p.Article

Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasivenessGUARINO, Valentina; FAVIANA, Pinuccia; SANTORO, Massimo et al.The Journal of clinical endocrinology and metabolism. 2005, Vol 90, Num 9, pp 5270-5278, issn 0021-972X, 9 p.Article

Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cellsCASTELLONE, Maria Domenica; CELETTI, Angela; FUSCO, Alfredo et al.Oncogene (Basingstoke). 2004, Vol 23, Num 12, pp 2188-2196, issn 0950-9232, 9 p.Article

RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein RhoBARONE, Maria Vittoria; SEPE, Leandra; MELILLO, Rosa Marina et al.Oncogene (Basingstoke). 2001, Vol 20, Num 48, pp 6973-6982, issn 0950-9232Article

BRAF is a therapeutic target in aggressive thyroid carcinomaSALVATORE, Giuliana; DE FALCO, Valentina; SALERNO, Paolo et al.Clinical cancer research. 2006, Vol 12, Num 5, pp 1623-1629, issn 1078-0432, 7 p.Article

Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomasCASTELLONE, Maria D; GUARINO, Valentina; FUSCO, Alfredo et al.Oncogene (Basingstoke). 2004, Vol 23, Num 35, pp 5958-5967, issn 0950-9232, 10 p.Article

Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteinsSALVATORE, Domenico; BARONE, Maria Vittoria; SALVATORE, Giuliana et al.The Journal of clinical endocrinology and metabolism. 2000, Vol 85, Num 10, pp 3898-3907, issn 0021-972XArticle

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cellsVITAGLIANO, Donata; CARLOMAGNO, Francesca; SANTORO, Massimo et al.Cancer research (Baltimore). 2004, Vol 64, Num 11, pp 3823-3829, issn 0008-5472, 7 p.Article

The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinomaMELILLO, Rosa Marina; CIRAFICI, Anna Maria; SANTORO, Massimo et al.The American journal of pathology. 2004, Vol 165, Num 2, pp 511-521, issn 0002-9440, 11 p.Article

Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinomaBASOLO, Fulvio; GIANNINI, Riccardo; MICCOLI, Paolo et al.The American journal of pathology. 2002, Vol 160, Num 1, pp 247-254, issn 0002-9440Article

Serum soluble ST2 and interleukin-33 levels in patients with pulmonary arterial hypertensionCARLOMAGNO, Guido; MESSALLI, Giancarlo; FAZIO, Serafino et al.International journal of cardiology. 2013, Vol 168, Num 2, pp 1545-1547, issn 0167-5273, 3 p.Article

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPaseDE FALCO, Valentina; CASTELLONE, Maria Domenica; DE VITA, Gabriella et al.Cancer research (Baltimore). 2007, Vol 67, Num 1, pp 381-390, issn 0008-5472, 10 p.Article

A Cell Proliferation and Chromosomal Instability Signature in Anaplastic Thyroid CarcinomaSALVATORE, Giuliana; CLAUDIO NAPPI, Tito; MELILLO, Rosa Marina et al.Cancer research (Baltimore). 2007, Vol 67, Num 21, pp 10148-10158, issn 0008-5472, 11 p.Article

Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasivenessCELETTI, Angela; TESTA, Domenico; GALLI, Vieri et al.Clinical cancer research. 2005, Vol 11, Num 22, pp 8019-8027, issn 1078-0432, 9 p.Article

Protein kinase Cα activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinaseANDREOZZI, Francesco; MELILLO, Rosa Marina; FORMISANO, Pietro et al.Oncogene (Basingstoke). 2003, Vol 22, Num 19, pp 2942-2949, issn 0950-9232, 8 p.Article

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenesCASTELLONE, Maria Domenica; CIRAFICI, Anna Maria; DE VITA, Gabriella et al.Oncogene (Basingstoke). 2003, Vol 22, Num 2, pp 246-255, issn 0950-9232, 10 p.Article