Biology of chronic myeloid leukemia and possible therapeutic approaches to imatinib-resistant disease : Current therapeutic approach for chronic myeloid/Myeloproliferative disorder: Focus on imatinib mesylateYOSHIDA, Chikashi; MELO, Junia V.International journal of hematology. 2004, Vol 79, Num 5, pp 420-433, issn 0925-5710, 14 p.Article

Chronic myeloid leukemia: Advances in biology and new approaches to treatmentGOLDMAN, John M; MELO, Junia V.The New England journal of medicine. 2003, Vol 349, Num 15, pp 1451-1464, issn 0028-4793, 14 p.Article

Cytogenetic and molecular genetic aspects of chronic myeloid leukaemiaBARNES, David J; MELO, Junia V.Acta haematologica. 2002, Vol 108, Num 4, pp 180-202, issn 0001-5792, 23 p.Article

Management of chronic myeloid leukemia: Targets for molecular therapyBARNES, David J; MELO, Junia V.Seminars in hematology. 2003, Vol 40, Num 1, pp 34-49, issn 0037-1963, 16 p.Article

The molecular biology of chronic myeloid leukemiaDEININGER, Michael W. N; GOLDMAN, John M; MELO, Junia V et al.Blood. 2000, Vol 96, Num 10, pp 3343-3356, issn 0006-4971Article

Dose-dependent effects of Bcr-Abl in cell line models of different stages of chronic myeloid leukemiaBARNES, David J; SCHULTHEIS, Beate; ADEDEJI, Simisade et al.Oncogene (Basingstoke). 2005, Vol 24, Num 42, pp 6432-6440, issn 0950-9232, 9 p.Article

Biology of chronic myelogenous leukemia-signaling pathways of initiation and transformationMELO, Junia V; DEININGER, Michael W. N.Hematology/oncology clinics of North America. 2004, Vol 18, Num 3, pp vii-viii, issn 0889-8588, 26 p.Article

Restoration of sensitivity to STI571 in STI571-resistant chronic myeloid leukemia cellsTIPPING, Alex J; MAHON, Francois X; LAGARDE, Valerie et al.Blood. 2001, Vol 98, Num 13, pp 3864-3867, issn 0006-4971Article

Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336HOOVER, Russell R; MAHON, Francois-Xavier; MELO, Junia V et al.Blood. 2002, Vol 100, Num 3, pp 1068-1071, issn 0006-4971Article

Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycinLY, Chi; ARECHIGA, Adrian F; MELO, Junia V et al.Cancer research (Baltimore). 2003, Vol 63, Num 18, pp 5716-5722, issn 0008-5472, 7 p.Article

Functional ABCG2 is overexpressed on primary CML CD34⁺ cells and is inhibited by imatinib mesylate. CommentaryMELO, Junia V; JORDANIDES, Niove E; JORGENSEN, Heather G et al.Blood. 2006, Vol 108, Num 4, issn 0006-4971, 1116-1117,1370-1373 [6 p.]Article

Association between BMI-1 expression, acute graft-versus-host disease, and outcome following allogeneic stem cell transplantation from HLA-identical siblings in chronic myeloid leukemiaMOHTY, Mohamad; SZYDLO, Richard M; YONG, Agnes S. M et al.Blood. 2008, Vol 112, Num 5, pp 2163-2166, issn 0006-4971, 4 p.Article

The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemiaMOHTY, Mohamad; YONG, Agnes S. M; SZYDLO, Richard M et al.Blood. 2007, Vol 110, Num 1, pp 380-383, issn 0006-4971, 4 p.Article

In search of the original leukemic clone in chronic myeloid leukemia patients in complete molecular remission after stem cell transplantation or imatinibSOBRINHO-SIMOES, Manuel; WILCZEK, Vicki; SCORE, Joannah et al.Blood. 2010, Vol 116, Num 8, pp 1329-1335, issn 0006-4971, 7 p.Article

Transient response to imatinib mesylate (STI571) in a patient with the ETV6-ABL t(9;12) translocationO'BRIEN, Stephen G; VIEIRA, Sara A. D; CONNORS, Samantha et al.Blood. 2002, Vol 99, Num 9, pp 3465-3467, issn 0006-4971Article

Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase geneGARIN, Marina I; GARRETT, Elaine; TIBERGHIEN, Pierre et al.Blood. 2001, Vol 97, Num 1, pp 122-129, issn 0006-4971Article

Abnormalities in Glucose Uptake and Metabolism in lmatinib-Resistant Human BCR-ABL-Positive CellsKOMINSKY, Douglas J; KLAWITTER, Jelena; BROWN, Jaimi L et al.Clinical cancer research (Print). 2009, Vol 15, Num 10, pp 3442-3450, issn 1078-0432, 9 p.Article

Molecular profiling of CD34⁺ cells identifies low expression of CD7, along with high expression of proteinase 3 or elastase, as predictors of longersurvival in patients with CMLYONG, Agnes S. M; SZYDLO, Richard M; GOLDMAN, John M et al.Blood. 2006, Vol 107, Num 1, pp 205-212, issn 0006-4971, 8 p.Article

MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line modelsMAHON, Francois-Xavier; BELLOC, Francis; LAGARDE, Valérie et al.Blood. 2003, Vol 101, Num 6, pp 2368-2373, issn 0006-4971, 6 p.Article

Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanismSCHULTHEIS, Beate; CARAPETI-MAROOTIAN, Melina; HOCHHAUS, Andreas et al.Blood. 2002, Vol 99, Num 5, pp 1766-1775, issn 0006-4971Article

Enhanced Bcr-Abl-specific antileukemic activity of arsenic trioxide through glutathione-depletion in imatinib-resistant cellsKONIG, Heiko; HARTEL, Nicolai; SCHULTHEIS, Beate et al.Haematologica (Roma). 2007, Vol 92, Num 6, pp 838-841, issn 0390-6078, 4 p.Article

The use of isobaric tag peptide labeling (iTRAQ) and mass spectrometry to examine rare, primitive hematopoietic cells from patients with chronic myeloid leukemiaGRIFFITHS, Stephen D; BURTHEM, John; UNWIN, Richard D et al.Molecular biotechnology. 2007, Vol 36, Num 2, pp 81-89, issn 1073-6085, 9 p.Article

Imatinib mesylate in combination with other chemotherapeutic drugs: In vitro studiesTIPPING, Alex J; MELO, Junia V.Seminars in hematology. 2003, Vol 40, Num 2, pp 83-91, issn 0037-1963, 9 p., SUP2Conference Paper

Imatinib mesylate (STI-571) reduces Bcr-Abl-mediated vascular endothelial growth factor secretion in chronic myelogenous leukemiaEBOS, John M. L; TRAN, Jennifer; MASTER, Zubin et al.Molecular cancer research. 2002, Vol 1, Num 2, pp 89-95, issn 1541-7786, 7 p.Article

Allorestricted cytotoxic T cells specific for human CD45 show potent antileukemic activityAMROLIA, Persis J; REID, Steven D; LIQUAN GAO et al.Blood. 2003, Vol 101, Num 3, pp 1007-1014, issn 0006-4971, 8 p.Article