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Results 1 to 25 of 41

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Therapeutic potential for microRNAsESAU, Christine C; MONIA, Brett P.Advanced drug delivery reviews. 2007, Vol 59, Num 2-3, pp 101-114, issn 0169-409X, 14 p.Article

Antisense approaches for the treatment of cancerMONIA, Brett P; HOLMLUND, Jon; DORR, F. Andrew et al.Cancer investigation. 2000, Vol 18, Num 7, pp 635-650, issn 0735-7907Article

Telomerase inhibition, telomere shortening, and decreased cell proliferation by cell permeable 2'-O-methoxyethyl oligonucleotidesZHI CHEN; MONIA, Brett P; COREY, David R et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 25, pp 5423-5425, issn 0022-2623, 3 p.Article

Comparison of strategies targeting Raf-1 mRNA in ovarian cancerMULLEN, Peter; MCPHILLIPS, Fiona; MONIA, Brett P et al.International journal of cancer. 2006, Vol 118, Num 6, pp 1565-1571, issn 0020-7136, 7 p.Article

Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasisKHATIB, Abdel-Majid; FALLAVOLLITA, Lucia; WANCEWICZ, Edward V et al.Cancer research (Baltimore). 2002, Vol 62, Num 19, pp 5393-5398, issn 0008-5472, 6 p.Article

Reduction of JNK1 expression with antisense oligonucleotide improves adiposity in obese miceXING XIAN YU; MURRAY, Susan F; WATTS, Lynnetta et al.American journal of physiology. Endocrinology and metabolism. 2008, Vol 58, Num 2, issn 0193-1849, E436-E445Article

Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cellsKIM, Youngsoo; JOON WON YOON; XIAOKUN XIAO et al.Cancer research (Baltimore). 2007, Vol 67, Num 8, pp 3583-3593, issn 0008-5472, 11 p.Article

In vivo suppression of Bcl-XL expression facilitates chemotherapy-induced leukaemia cell death in a SCID/NOD-Hu modelFENNELL, Dean A; CORBO, Margherita V; DEAN, Nicholas M et al.British journal of haematology. 2001, Vol 112, Num 3, pp 706-713, issn 0007-1048Article

Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expressionXING XIAN YU; PANDEY, Sanjay K; BOOTEN, Sheri L et al.American journal of physiology. Endocrinology and metabolism. 2008, Vol 57, Num 3, issn 0193-1849, E530-E539Article

Mcl-1 is a novel therapeutic target for human sarcoma: Synergistic inhibition of human sarcoma xenotransplants by a combination of Mcl-1 antisense oligonucleotides with low-dose cyclophosphamideTHALLINGER, Christiane; WOLSCHEK, Markus F; MAIERHOFER, Helmut et al.Clinical cancer research. 2004, Vol 10, Num 12, pp 4185-4191, issn 1078-0432, 7 p., 1Article

PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cellsYONG CHOI; JIE ZHANG; MURGA, Cristina et al.Oncogene (Basingstoke). 2002, Vol 21, Num 34, pp 5289-5300, issn 0950-9232Article

Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotypeBIN PAN; YAO, Kang-Shen; MONIA, Brett P et al.Biochemical pharmacology. 2002, Vol 63, Num 8, pp 1699-1707, issn 0006-2952Article

Mcl-1 blocks radiation-induced apoptosis and inhibits clonogenic cell deathSKVARA, Hans; THALLINGER, Christiane; WACHECK, Volker et al.Anticancer research. 2005, Vol 25, Num 4, pp 2697-2703, issn 0250-7005, 7 p.Article

Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicityHAYWARD, Richard L; MACPHERSON, Janet S; CUMMINGS, Jeff et al.Clinical cancer research. 2003, Vol 9, Num 7, pp 2856-2865, issn 1078-0432, 10 p.Article

An antisense oligonucleotide targeted to human Ku86 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agentsBELENKOV, Alexandre I; PAIEMENT, Jean-Pierre; PANASCI, Lawrence C et al.Cancer research (Baltimore). 2002, Vol 62, Num 20, pp 5888-5896, issn 0008-5472, 9 p.Article

Role of Ras isoforms in the stimulated proliferation of human renal fibroblasts in primary cultureSHARPE, Claire C; DOCKRELL, Mark E. C; NOOR, Mazhar I et al.Journal of the American Society of Nephrology. 2000, Vol 11, Num 9, pp 1600-1606, issn 1046-6673Article

Diacylglycerol Acyltranferase 1 Anti-Sense Oligonucleotides Reduce Hepatic Fibrosis in Mice With Nonalcoholic SteatohepatitisYAMAGUCHI, Kanji; LIU YANG; MCCALL, Shannon et al.Hepatology (Baltimore, Md.). 2008, Vol 47, Num 2, pp 625-635, issn 0270-9139, 11 p.Article

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitisYAMAGUCHI, Kanji; LIU YANG; MCCALL, Shannon et al.Hepatology (Baltimore, Md.). 2007, Vol 45, Num 6, pp 1366-1374, issn 0270-9139, 9 p.Article

Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesisRONDINONE, Cristina M; TREVILLYAN, James M; BUTLER, Madeline et al.Diabetes (New York, NY). 2002, Vol 51, Num 8, pp 2405-2411, issn 0012-1797Article

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic miceBUTLER, Madeline; MCKAY, Robert A; POPOFF, Ian J et al.Diabetes (New York, NY). 2002, Vol 51, Num 4, pp 1028-1034, issn 0012-1797Article

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domainHOROWITZ, Netanel A; BLEVINS, Elizabeth A; CONWAY, Edward M et al.Blood. 2011, Vol 118, Num 10, pp 2889-2895, issn 0006-4971, 7 p.Article

Antisense OligonucleotideTargeting of Insulin-like Growth Factor-I Receptor (IGF-IR) in Prostate CancerFURUKAWA, Junya; WRAIGHT, Christopher J; FREIER, Susan M et al.The Prostate. 2010, Vol 70, Num 2, pp 206-218, issn 0270-4137, 13 p.Article

Raf-1 is the predominant Raf isoform that mediates growth factor-stimulated growth in ovarian cancer cellsMCPHILLIPS, Fiona; MULLEN, Peter; MACLEOD, Kenneth G et al.Carcinogenesis (New York. Print). 2006, Vol 27, Num 4, pp 729-739, issn 0143-3334, 11 p.Article

Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonismWATTS, Lynnetta M; VARA PRASAD MANCHEM; HONG YAN ZHANG et al.Diabetes (New York, NY). 2005, Vol 54, Num 6, pp 1846-1853, issn 0012-1797, 8 p.Article

Antisense oligodeoxynucleotides for urokinase-plasminogen activator receptor have anti-invasive and anti-proliferative effects in vitro and inhibit spontaneous metastases of human melanoma in miceD'ALESSIO, Silvia; MARGHERI, Francesca; DEL ROSSO, Mario et al.International journal of cancer. 2004, Vol 110, Num 1, pp 125-133, issn 0020-7136, 9 p.Article

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