Endocannabinoid biosynthesis and inactivation, from simple to complexMUCCIOLI, Giulio G.Drug discovery today. 2010, Vol 15, Num 11-12, pp 474-483, issn 1359-6446, 10 p.Article

Functionally selective cannabinoid receptor signalling: Therapeutic implications and opportunitiesBOSIER, Barbara; MUCCIOLI, Giulio G; HERMANS, Emmanuel et al.Biochemical pharmacology. 2010, Vol 80, Num 1, pp 1-12, issn 0006-2952, 12 p.Article

Binding mode of new (thio)hydantoin inhibitors of fatty acid amide hydrolase : Comparison with two original compounds, OL-92 and JP104MICHAUX, Catherine; MUCCIOLI, Giulio G; LAMBERT, Didier M et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 18, pp 4772-4776, issn 0960-894X, 5 p.Article

Synthesis and in Vitro Evaluation of N-Substituted Maleimide Derivatives as Selective Monoglyceride Lipase InhibitorsMATUSZAK, Nicolas; MUCCIOLI, Giulio G; LABAR, Geoffray et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 23, pp 7410-7420, issn 0022-2623, 11 p.Article

Bis(dialkylaminethiocarbonyl)disulfides as Potent and Selective Monoglyceride Lipase InhibitorsKAPANDA, Coco N; MUCCIOLI, Giulio G; LABAR, Geoffray et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 22, pp 7310-7314, issn 0022-2623, 5 p.Article

3-Alkenyl-2-azetidinones as fatty acid amide hydrolase inhibitorsURBACH, Allan; MUCCIOLI, Giulio G; STERN, Eric et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 4163-4167, issn 0960-894X, 5 p.Article

Characterization of the pharmacology of imidazolidinedione derivatives at cannabinoid CB₁ and CB₂ receptorsGOVAERTS, Sophie J; MUCCIOLI, Giulio G; HERMANS, Emmanuel et al.European journal of pharmacology. 2004, Vol 495, Num 1, pp 43-53, issn 0014-2999, 11 p.Article

Chemistry around imidazopyrazine and ibuprofen: Discovery of novel fatty acid amide hydrolase (FAAH) inhibitorsDE WAEL, Frédéric; MUCCIOLI, Giulio G; LAMBERT, Didier M et al.European journal of medicinal chemistry. 2010, Vol 45, Num 9, pp 3564-3574, issn 0223-5234, 11 p.Article

PET imaging of fatty acid amide hydrolase in the brain: synthesis and biological evaluation of an ¹¹C-labelled URB597 analogueWYFFELS, Leonie; MUCCIOLI, Giulio G; KAPANDA, Coco N et al.Nuclear medicine and biology. 2010, Vol 37, Num 5, pp 665-675, issn 0969-8051, 11 p.Article

Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB₂ cannabinoid receptors agonists : Synthesis, pharmacological properties and molecular modelingSTERN, Eric; MUCCIOLI, Giulio G; MILLET, Régis et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 1, pp 70-79, issn 0022-2623, 10 p.Article

Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB₁ cannabinoid receptor ligands : synthesis and pharmacological evaluationMUCCIOLI, Giulio G; MARTIN, Diana; SCRIBA, Gerhard K. E et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 7, pp 2509-2517, issn 0022-2623, 9 p.Article

Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed miceDEWULF, Evelyne M; CANI, Patrice D; MIGNOLET, Eric et al.Journal of nutritional biochemistry. 2011, Vol 22, Num 8, pp 712-722, issn 0955-2863, 11 p.Article

Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templatesMUCCIOLI, Giulio G; FAZIO, Nicola; SCRIBA, Gerhard K. E et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 1, pp 417-425, issn 0022-2623, 9 p.Article

Synthesis, In Vitro and In Vivo Evaluation, and Radiolabeling of Aryl Anandamide Analogues as Candidate Radioligands for In Vivo Imaging of Fatty Acid Amide Hydrolase in the BrainWYFFELS, Leonie; MUCCIOLI, Giulio G; DE BRUYNE, Sylvie et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 15, pp 4613-4622, issn 0022-2623, 10 p.Article

Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compoundsHOET, Sara; PIETERS, Luc; MUCCIOLI, Giulio G et al.Journal of natural products (Print). 2007, Vol 70, Num 8, pp 1360-1363, issn 0163-3864, 4 p.Article

1-benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives : New templates among the CB₁ cannabinoid receptor inverse agonistsMUCCIOLI, Giulio G; WOUTERS, Johan; SCRIBA, Gerhard K. E et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 23, pp 7486-7490, issn 0022-2623, 5 p.Article

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitisANDRZEJAK, Virginie; MUCCIOLI, Giulio G; BODY-MALAPEL, Mathilde et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 12, pp 3777-3786, issn 0968-0896, 10 p.Article

β-Lactams Derived from a Carbapenem Chiron Are Selective Inhibitors of Human Fatty Acid Amide Hydrolase versus Human Monoacylglycerol LipaseFELEDZIAK, Marion; MICHAUX, Catherine; URBACH, Allan et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 22, pp 7054-7068, issn 0022-2623, 15 p.Article

Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growthMATUSZAK, Nicolas; HAMTIAUX, Laurie; BALDEYROUX, Brigitte et al.European journal of pharmaceutical sciences. 2012, Vol 45, Num 3, pp 263-271, issn 0928-0987, 9 p.Article

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imagingEVENS, Nele; VANDEPUTTE, Caroline; MUCCIOLI, Giulio G et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 15, pp 4499-4505, issn 0968-0896, 7 p.Article

Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5 -triphenyl -2 -thioxoimidazolidin-4-ones : Characterization of new CB₁ cannabinoid receptor inverse agonists/antagonistsMUCCIOLI, Giulio G; WOUTERS, Johan; CHARLIER, Caroline et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 3, pp 872-882, issn 0022-2623, 11 p.Article

Pharmacomodulations around the 4 -oxo -1,4 -dihydroquinoline -3 -carboxamides, a class of potent CB₂-selective cannabinoid receptor ligands : Consequences in receptor affinity and functionalitySTEM, Eric; MUCCIOLI, Giulio G; BOSIER, Barbara et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 22, pp 5471-5484, issn 0022-2623, 14 p.Article