Bioreductive therapies : An overview of drugs and their mechanisms of actionRAUTH, A. M; MELO, T; MISRA, V et al.International journal of radiation oncology, biology, physics. 1998, Vol 42, Num 4, pp 755-762, issn 0360-3016Conference Paper

5-Fluorouracil infusions and fractionated doses of radiation: studies with a murine squamous cell carcinomaWEINBERG, M. J; RAUTH, A. M.International journal of radiation oncology, biology, physics. 1987, Vol 13, Num 11, pp 1691-1699, issn 0360-3016Article

Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour modelsBALLINGER, J. R; HSUE, V; RAUTH, A. M et al.Nuclear medicine communications. 2003, Vol 24, Num 5, pp 597-606, issn 0143-3636, 10 p.Article

Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin CKUEHL, B. L; BUCHWALD, M; RAUTH, A. M et al.Oncology research. 1993, Vol 5, Num 6-7, pp 213-221, issn 0965-0407Article

Mode of interaction of 5-fluorouracil, radiation, and mitomycin c: in vitro studiesDOBROWSKY, W; DOBROWSKY, E; RAUTH, A. M et al.International journal of radiation oncology, biology, physics. 1992, Vol 22, Num 5, pp 875-880, issn 0360-3016Article

Role of NADPH:Cytochrome P450 reductase in the hypoxic accumulation and metabolism of BRU59-21, a technetium-99m-nitroimidazole for imaging tumor hypoxiaMELO, T; BALLINGER, J. R; RAUTH, A. M et al.Biochemical pharmacology. 2000, Vol 60, Num 5, pp 625-634, issn 0006-2952Article

Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxine (SR 4233)LADEROUTE, K; WARDMAN, P; RAUTH, A. M et al.Biochemical pharmacology. 1988, Vol 37, Num 8, pp 1487-1495, issn 0006-2952Article

Products of the reactions of 2-nitroimidazolesMCCLELLAND, R. A; PANICUCCI, R; RAUTH, A. M et al.Journal of the American Chemical Society. 1987, Vol 109, Num 14, pp 4308-4314, issn 0002-7863Article

Oxygen and exposure kinetics as factors influencing the cytotoxicity of porfiromycin, a mitomycin C analogue, in Chinese hamster ovary cellsMARSHALL, R. S; RAUTH, A. M.Cancer research (Baltimore). 1988, Vol 48, Num 20, pp 5655-5659, issn 0008-5472Article

Identification of two major reduction products of the hypoxic cell toxin 3-amino-1,2,4-benzotriazine-1,4-dioxideLADEROUTE, K. R; RAUTH, A. M.Biochemical pharmacology. 1986, Vol 35, Num 19, pp 3417-3420, issn 0006-2952Article

Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutantMARSHALL, R. S; RAUTH, A. M.Cancer research (Baltimore). 1986, Vol 46, Num 6, pp 2709-2713, issn 0008-5472Article

Electrophilic intermediate in the reactions of a 2-(hydroxylamino)imidazole. A model for biological effects of reduced nitroimidazolesMCCLELLAND, R. A; PANICUCCI, R; RAUTH, A. M et al.Journal of the American Chemical Society. 1985, Vol 107, Num 6, pp 1762-1763, issn 0002-7863Article

A bioassay to measure cytotoxicity of plasma from patients treated with mitomycin CMARSHALL, R. S; ERLICHMAN, C; RAUTH, A. M et al.Cancer research (Baltimore). 1985, Vol 45, Num 11, pp 5939-5943, issn 0008-5472Article

Cellular accumulation and retention of the technetium-99m-labelled hypoxia markers BRU59-21 and butylene amine oximeXIUGUO ZHANG; MELO, Tricia; RAUTH, A. M et al.Nuclear medicine and biology. 2001, Vol 28, Num 8, pp 949-957, issn 0969-8051Article

Cellular approaches to bioreductive drug mechanismsRAUTH, A. M; MARSHALL, R. S; KUEHL, B. L et al.Cancer metastasis reviews. 1993, Vol 12, Num 2, pp 153-164, issn 0167-7659Article

Radiosensitizing and cytotoxic properties of DNA targeted phenanthridine-linked nitroheterocycles of varying electron affinitiesCOWAN, D. S. M; MATEJOVIC, J. F; WARDMAN, P et al.International journal of radiation biology (Print). 1994, Vol 66, Num 6, pp 729-738, issn 0955-3002Article

Mechanistic studies of enhanced in vitro radiosensitization and hypoxic cell cytotoxicity by targeting radiosensitizers to DNA via intercalationCOWAN, D. S. M; KANAGASABAPATHY, V. M; MCCLELLAND, R. A et al.International journal of radiation oncology, biology, physics. 1992, Vol 22, Num 3, pp 541-544, issn 0360-3016Conference Paper

Prostate-specific antigen induction by a steroid hormone in T47D cells growing in SCID miceKOGAN, I; BALLINGER, J. R; REDSHAW, R et al.Breast cancer research and treatment. 1998, Vol 48, Num 1, pp 73-80, issn 0167-6806Article

Role of a DT-diaphorase mutation in the response of anal canal carcinoma to radiation, 5-fluorouracil, and mitomycin CGOLDBERG, Z. I; CUMMINGS, B. J; CHAPMAN, W. B et al.International journal of radiation oncology, biology, physics. 1998, Vol 42, Num 2, pp 331-334, issn 0360-3016Article

Studies of ^99mTc-BnAO (HL-91) : A non-nitroaromatic compound for hypoxic cell detectionZHANG, X; MELO, T; BALLINGER, J. R et al.International journal of radiation oncology, biology, physics. 1998, Vol 42, Num 4, pp 737-740, issn 0360-3016Conference Paper

Mechanism of ultrasound enhanced porphyrin cytotoxicity. Part I: A search for free radical effectsWORTHINGTON, A. E; THOMPSON, J; RAUTH, A. M et al.Ultrasound in medicine & biology. 1997, Vol 23, Num 7, pp 1095-1105, issn 0301-5629Article

Use of a high frequency ultrasound microscope to image the action of 2-nitroimidazoles in multicellular spheroidsBERUBE, L. R; HARASIEWICZ, K; FOSTER, F. S et al.British journal of cancer. 1992, Vol 65, Num 5, pp 633-640, issn 0007-0920Article

Depletion of intracellular glutathione by 1-methyl-2-nitrosoimidazoleBERUBE, L. R; FARAH, S; MCCLELLAND, R. A et al.International journal of radiation oncology, biology, physics. 1992, Vol 22, Num 4, pp 817-820, issn 0360-3016Conference Paper

Isolation and characterization of a cell line resistant to 5-[3-(2-nitro-1-imidazoyl)-propyl]-phenanthridinium bromide (2-NLP-3), a DNA-intercalating hypoxic cell radiosensitizer and cytotoxinCOWAN, D. S. M; MCCLELLAND, R. A; RAUTH, A. M et al.Biochemical pharmacology. 1995, Vol 50, Num 1, pp 61-68, issn 0006-2952Article

DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone familyMARSHALL, R. S; PATERSON, M. C; RAUTH, A. M et al.Carcinogenesis (New York. Print). 1991, Vol 12, Num 7, pp 1175-1180, issn 0143-3334, 6 p.Article