NON-COMPETITIVE AND COMPETITIVE INHIBITION OF MIXED FUNCTION OXIDASE IN RAT LIVER MICROSOMES BY METYRAPONEROOTS I; HILDEBRANDT AG.1973; ARCH. (NAUNYN-SCHMIEDEBERG'S) PHARMACOL.; GERM.; DA. 1973; VOL. 277; NO 1; PP. 27-38; BIBL. 1P.Serial Issue

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (NADPH)-DEPENDENT FORMATION AND BREAKDOWN OF HYDROGEN PEROXIDE DURING MIXED FUNCTION OXIDATION REACTIONS IN LIVER MICROSOMES. = FORMATION ET DEGRADATION NADPH-DEPENDANTES DE PEROXYDE D'HYDROGENE AU COURS DES REACTIONS D'OXYDATION A FONCTION MIXTE DANS LES MICROSOMES DE FOIEHILDEBRANDT AG; ROOTS I.1975; ARCH. BIOCHEM. BIOPLYS.; U.S.A.; DA. 1975; VOL. 171; NO 2; PP. 385-397; BIBL. 37 REF.Article

ACTIVE CENTERS OF MICROSOMAL CYTOCHROME P-450 DETERMINED WITH METYRAPONE BY MUTUAL DEPLETION SYSTEM KINETICS = CENTRES ACTIFS DU CYTOCHROME P450 DES MICROSOMES, DETERMINES A L'AIDE DU METYRAPONE PAR LA CINETIQUE DU SYSTEME DEPLETEUR MUTUELROOTS I; HILDEBRANDT AG.1973; ARCH. (NAUNYN-SCHMIEDEBERG'S) PHARMACOL.; GERM.; DA. 1973; VOL. 277; NO 1; PP. 39-52; BIBL. 1P.1/2Serial Issue

STOICHIOMETRIC COOPERATION OF NADPH AND HEXOBARBITAL IN HEPATIC MICROSOMES DURING THE CATALYSIS OF HYDROGEN PEROXIDE FORMATIONHILDEBRANDT AG; HEINEMEYER G; ROOTS I et al.1982; ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; ISSN 0003-9861; USA; DA. 1982; VOL. 216; NO 2; PP. 455-465; BIBL. 32 REF.Article

URINARY EXCRETION OF D-GLUCARIC ACID, AN INDICATOR OF DRUG METABOLIZING ENZYME ACTIVITY, IN PATIENTS WITH IMPAIRED RENAL FUNCTIONKAMPF D; ROOTS I; HILDEBRANDT AG et al.1980; EUR. J. CLIN. PHARMACOL.; ISSN 0031-6970; DEU; DA. 1980; VOL. 18; NO 3; PP. 255-261; BIBL. 31 REF.Article

Pitfalls in N-acetyltransferase 2 genotypingCASCORBI, I; ROOTS, I.Pharmacogenetics (London). 1999, Vol 9, Num 1, pp 123-127, issn 0960-314XArticle

Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios : coincidence with plasma clearance and breath testROST, K. L; ROOTS, I.Clinical pharmacology and therapeutics. 1994, Vol 55, Num 4, pp 402-411, issn 0009-9236Article

Benzo(a) pyrene metabolism in hepatic microsomes from female DA rats with a genetic sparteine oxidation deficiencySCHLEDE, E; ROOTS, I.Toxicology letters. 1985, Vol 29, Num 1, pp 5-10, issn 0378-4274Article

Nonlinear kinetics after high-dose omeprazole caused by saturation of genetically variable CYP2C19ROST, K. L; ROOTS, I.Hepatology (Baltimore, Md.). 1996, Vol 23, Num 6, pp 1491-1497, issn 0270-9139Article

Assessment of liver metabolic function : clinical implicationsBROCKMÖLLER, J; ROOTS, I.Clinical pharmacokinetics. 1994, Vol 27, Num 3, pp 216-248, issn 0312-5963Article

EVALUATION OF IN VIVO PARAMETERS OF DRUG METABOLIZING ENZYME ACTIVITY IN MAN AFTER ADMINISTRATION OF CLEMASTINE, PHENOBARBITAL OR PLACEBO = EVALUATION IN VIVO DES PARAMETRES D'ACTIVITE DES ENZYMES METABOLISANT LES MEDICAMENTS APRES ADMINISTRATION DE CLEMASTINE, PHENOBARBITOL OU PLACEBOHILDEBRANDT AG; ROOTS I; SPECK M et al.1975; EUROP. J. CLIN. PHARMACOL.; GERM.; DA. 1975; VOL. 8; NO 5; PP. 327-336; BIBL. 1 P. 1/2Article

Autoremeferate/Deutsche Arbeitsgemeinschaft zum Studium der Leber, 4. Tagung, Berlin, 29-30 Januar 1988 = Comptes rendus d'auteurs/Association allemande pour l'étude du foie, 4ème réunion, Berlin, 29-30 janvier 1988 = Abstracts/German Association for the Study of the Liver, 4th. meeting, Berlin, January 29-30, 1988ROOTS, I.Zeitschrift für Gastroenterologie. 1988, Vol 26, Num 1, pp 1-103, issn 0044-2771Conference Proceedings

Acute poisoning with bromofosmethyl (bromophos)KOPPEL, C; THOMSEN, T; HEINEMEYER, G et al.Journal of toxicology. Clinical toxicology. 1991, Vol 29, Num 2, pp 203-207, issn 0731-3810, 5 p.Article

QUANTITATIVE DETERMINATION BY HPLC OF URINARY 6BETA -HYDROXYCORTISOL, AN INDICATOR OF ENZYME INDUCTION BY RIFAMPICIN AND ANTIEPILEPTIC DRUGSROOTS I; HOLBE R; HOEVERMANN W et al.1979; EUROP. J. CLIN. PHARMACOL.; DEU; DA. 1979; VOL. 16; NO 1; PP. 63-71; BIBL. 38 REF.Article

Deficiency of glutathione S-transferases T1 and M1 as heritable factors of increased cutaneous UV sensitivityKERB, R; BROCKMÖLLER, J; REUM, T et al.Journal of investigative dermatology. 1997, Vol 108, Num 2, pp 229-232, issn 0022-202XArticle

Cytochrome P450 2D6 variants in a caucasian population : Allele frequencies and phenotypic consequencesSACHSE, C; BROCKMÖLLER, J; BAUER, S et al.American journal of human genetics. 1997, Vol 60, Num 2, pp 284-295, issn 0002-9297Article

Urinary 6β-hydroxycortisol and D-glucaric acid excretion rates are not affected by lansoprazole treatmentROST, K. L; MANSMANN, U; ROOTS, I et al.International journal of clinical pharmacology and therapeutics. 1997, Vol 35, Num 1, pp 14-18, issn 0946-1965Article

Mikromethode zur Bestimmung von Amrinon und Acetyl-amrinon in Plasma und Urin durch HPLC = HPLC-micromethod for the determination of amrinone and acetylamrinone in plasma and urineMIGULLA, H; BAUER, S; KEWITZ, H et al.Pharmazie. 1994, Vol 49, Num 4, pp 290-291, issn 0031-7144Article

Mutant genes of cytochrome P-450IID6, glutathione S-transferase class Mu, and arylamine N-acetyltransferase in lung cancer patientsROOTS, I; BROCKMÖLLER, J; DRAKOULIS, N et al.(The) Clinical investigator. 1992, Vol 70, Num 3-4, pp 307-319Article

Quantification of the antipsychotics flupentixol and haloperidol in human serum by high-performance liquid chromatography with ultraviolet detectionWALTER, S; BAUER, S; ROOTS, I et al.Journal of chromatography. B, Biomedical sciences and applications. 1998, Vol 720, Num 1-2, pp 231-237, issn 1387-2273Article

Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT)ROOTS, I; KUHLMANN, J.European journal of clinical pharmacology. Supplement. 1997, Vol 52, issn 0179-292X, 173 p.Conference Proceedings

A C4887A polymorphism in exon 7 of human CYP1A1 : Population frequency, mutation linkages, and impact on lung cancer susceptibilityCASCORBI, I; BROCKMÖLLER, J; ROOTS, I et al.Cancer research (Baltimore). 1996, Vol 56, Num 21, pp 4965-4969, issn 0008-5472Article

Polymorphic arylamine N-acetyltransferase (NAT2) genes in children with insulin-dependent diabetes mellitusMROZIKIEWICZ, P. M; DRAKOULIS, N; ROOTS, I et al.Clinical pharmacology and therapeutics. 1994, Vol 56, Num 6, pp 626-634, issn 0009-9236, 1Article

Evaluation of proposed sulphoxidation pathways of carbocysteine in man by HPLC quantificationBROCKMOLLER, J; STAFFELDT, B; ROOTS, I et al.European journal of clinical pharmacology. 1991, Vol 40, Num 4, pp 387-392, issn 0031-6970, 6 p.Article

Determination of S-carboxymethyl-L cysteine and some of its metabolites in urine and serum by high-performance liquid chromatography using fluorescent pre-column labellingSTAFFELDT, B; BROCKMÖLLER, J; ROOTS, I et al.Journal of chromatography. Biomedical applications. 1991, Vol 571, Num 1-2, pp 133-147, issn 0378-4347Article