Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (Rogletimide) and discovery of potent 5-alkyl derivativesMCCAGUE, R; ROWLANDS, M. G.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 20, pp 3699-3704, issn 0022-2623Article

3- and 4-Pyridylalkyl adamantanecarboxylates : Inhibitors of human cytochrome P450_17α (17α-hydroxylase/C_17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancerCHAN, F. C. Y; POTTER, G. A; BARRIE, S. E et al.Journal of medicinal chemistry (Print). 1996, Vol 39, Num 17, pp 3319-3323, issn 0022-2623Article

The deuterium isotope effect for the α-hydroxylation of tamoxifen by rat liver microsomes accounts for the reduced genotoxicity of [D₅-ethyl]tamoxifenJARMAN, M; POON, G. K; ROWLANDS, M. G et al.Carcinogenesis (New York. Print). 1995, Vol 16, Num 4, pp 683-688, issn 0143-3334Article

Prognostic significance of aromatase and estrone sulfatase enzymes in human breast cancerEVANS, T. R. J; ROWLANDS, M. G; SILVA, M. C et al.Journal of steroid biochemistry and molecular biology. 1993, Vol 44, Num 4-6, pp 583-587, issn 0960-0760Conference Paper

Oestrone sulphatase activity in mammary tumours and the liver of N-nitrosomethylurea treated ratsEVANS, T. R. J; CHANDER, S. K; ROWLANDS, M. G et al.British journal of cancer. 1992, Vol 65, Num 1, pp 72-76, issn 0007-0920Article

Inhibition of the formation of 4-hydroxyandrostenedione glucuronide by valproatePARR, I. B; ROWLANDS, M. G; HOUGHTON, J et al.Biochemical pharmacology. 1988, Vol 37, Num 23, pp 4581-4583, issn 0006-2952Article

A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1DRAYTER, S; ELLIOTT, R; LORD, C. J et al.Oncogene (Basingstoke). 2008, Vol 27, Num 8, pp 1036-1044, issn 0950-9232, 9 p.Article

Lack of inhibition of placental estrone sulfatase and aromatase enzymes by vitamin D₃ and its analogsEVANS, T. R. J; ROWLANDS, M. G; SAHOTA, S. S et al.Journal of steroid biochemistry and molecular biology. 1994, Vol 48, Num 5-6, pp 563-566, issn 0960-0760Article

Evidence that tamoxifen binds to calmodulin in a conformation different to that when binding to estrogen receptors, through structure-activity study on ring-fused analoguesMCCAGUE, R; ROWLANDS, M. G; GRIMSHAW, R et al.Biochemical pharmacology. 1994, Vol 48, Num 7, pp 1355-1361, issn 0006-2952Article

Inhibition of 17α-hydroxylase/C17-C20 lyase by bifluranol and its analoguesBARRIE, S. E; ROWLANDS, M. G; FOSTER, A. B et al.Journal of steroid biochemistry. 1989, Vol 33, Num 6, pp 1191-1195, issn 0022-4731, 5 p.Article

1-Alkyl analogues of aminoglutethimide: comparative inhibition of cholesterol side chain cleavage and aromate and metabolism of the 1-propyl derivative, a highly selective inhibitor of aromataseSEAGO, A; BAKER, M. H; HOUGHTON, J et al.Biochemical pharmacology. 1988, Vol 37, Num 11, pp 2167-2172, issn 0006-2952Article

Selective inhibition of cholesterol side-chain cleavage by potential pro-drug forms of aminoglutethimideJARMAN, M; BARRIE, S. E; LEUNG, C.-S et al.Anti-cancer drug design. 1988, Vol 3, Num 3, pp 185-190, issn 0266-9536Article

Analogues of aminoglutethimide: selective inhibition of aromataseFOSTER, A. B; JARMAN, M; CHUI-SHEUNG LEUNG et al.Journal of medicinal chemistry (Print). 1985, Vol 28, Num 2, pp 200-204, issn 0022-2623Article

Antiestrogens as calmodulin antagonistsHARDCASTLE, I. R; ROWLANDS, M. G; JARMAN, M et al.Current medicinal chemistry. 1996, Vol 3, Num 3, pp 211-226, issn 0929-8673Article

Comparison of biochemical aromatase activity with aromatase immunhistochemistry in human breast carcinomasSHENTON, K. C; DOWSETT, M; LU, Q et al.Breast cancer research and treatment. 1998, Vol 49, pp S101-S107, issn 0167-6806, SUP1Conference Paper

Antagonism of estrogen receptor and calmodulin association by antiestrogens is not dependent on an interaction with calmodulinROWLANDS, M. G; GRIMSHAW, R; JARMAN, M et al.Biochemical pharmacology. 1997, Vol 53, Num 2, pp 241-244, issn 0006-2952Article

Effects of 4-hydroxyandrost-4-ene-3,17-dione and its metabolites on 5α-reductase activity and the androgen receptorDAVIES, J. H; SHEARER, R. J; ROWLANDS, M. G et al.Journal of enzyme inhibition. 1992, Vol 6, Num 2, pp 141-147, issn 8755-5093Article

Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometryPOON, G. K; CHUI, Y. C; JARMAN, M et al.Drug metabolism and disposition. 1992, Vol 20, Num 6, pp 941-947, issn 0090-9556Article

Determination of 4-hydroxyandrost-4-ene-3,17-dione metabolism in breast cancer patients using high-performance liquid chromatography-mass spectrometryPOON, G. K; JARMAN, M; ROWLANDS, M. G et al.Journal of chromatography. Biomedical applications. 1991, Vol 565, Num 1-2, pp 75-88, issn 0378-4347Article

Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activityROWLANDS, M. G; BUNNETT, M. A; FOSTER, A. B et al.Journal of medicinal chemistry (Print). 1988, Vol 31, Num 5, pp 971-976, issn 0022-2623Article

Metabolism of aminoglutethimide in humansFOSTER, A. B; GRIGGS, L. J; HOWE, I et al.Drug metabolism and disposition. 1984, Vol 12, Num 4, pp 511-516, issn 0090-9556Article

Identification and characterization of limonene metabolites in patients with advanced cancer by liquid chromatography/mass spectrometryPOON, G. K; VIGUSHIN, D; GRIGGS, L.J et al.Drug metabolism and disposition. 1996, Vol 24, Num 5, pp 565-571, issn 0090-9556Article

Comparison between inhibition of protein kinase C and antagonism of calmodulin by tamoxifen analoguesROWLANDS, M. G; BUDWORTH, J; JARMAN, M et al.Biochemical pharmacology. 1995, Vol 50, Num 5, pp 723-726, issn 0006-2952Article

Novel steroidal inhibitors of human cytochrome P450_17α (17α-hydroxylase-C_17,20-lyase) : potential agents for the treatment of prostatic cancerPOTTER, G. A; BARRIE, S. E; JARMAN, M et al.Journal of medicinal chemistry (Print). 1995, Vol 38, Num 13, pp 2463-2471, issn 0022-2623Article

Rationally designed analogues of tamoxifen with improved calmodulin antagonismHARDCASTLE, I. R; ROWLANDS, M. G; HOUGHTON, J et al.Journal of medicinal chemistry (Print). 1995, Vol 38, Num 2, pp 241-248, issn 0022-2623Article