Comparison of the efficacy and skin permeability of topical NSAID preparations used in EuropeKOMATSU, Takaaki; SAKURADA, Tsukasa.European journal of pharmaceutical sciences. 2012, Vol 47, Num 5, pp 890-895, issn 0928-0987, 6 p.Article

Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphineMIZOGUCHI, Hirokazu; BAGETTA, Giacinto; SAKURADA, Tsukasa et al.Peptides (New York, NY. 1980). 2011, Vol 32, Num 2, pp 421-427, issn 0196-9781, 7 p.Article

Involvement of spinal NK₂ and NMDA receptors in aversive behavior induced by intra-arterial injection of capsaicinANDO, Ryuichiro; WATANABE, Chizuko; KAWAMURA, Syunsuke et al.Pharmacology, biochemistry and behavior. 2001, Vol 68, Num 1, pp 105-113, issn 0091-3057Article

Characterization of nociceptive responses and spinal releases of nitric oxide metabolites and glutamate evoked by different concentrations of formalin in ratsOKUDA, Kazuhiro; SAKURADA, Chikai; TAKAHASHI, Mitsuo et al.Pain (Amsterdam). 2001, Vol 92, Num 1-2, pp 107-115, issn 0304-3959Article

Antinociceptive effects of spinally administered nociceptin/orphanin FQ and its N-terminal fragments on capsaicin-induced nociceptionKATSUYAMA, Soh; MIZOGUCHI, Hirokazu; KOMATSU, Takaaki et al.Peptides (New York, NY. 1980). 2011, Vol 32, Num 7, pp 1530-1535, issn 0196-9781, 6 p.Article

A Tyr-W-MIF-1 analog containing D-Pro² discriminates among antinociception in mice mediated by different classes of μ-opioid receptorsNAKAYAMA, Daisuke; WATANABE, Chizuko; WATANABE, Hiroyuki et al.European journal of pharmacology. 2007, Vol 563, Num 1-3, pp 109-116, issn 0014-2999, 8 p.Article

Degradation of endomorphin-2 at the supraspinal level in mice is initiated by dipeptidyl peptidase IV: an in vitro and in vivo studySAKURADA, Chikai; SAKURADA, Shinobu; HAYASHI, Takafumi et al.Biochemical pharmacology. 2003, Vol 66, Num 4, pp 653-661, issn 0006-2952, 9 p.Article

Evidence that nitric oxide-glutamate cascade modulates spinal antinociceptive effect of morphine: a behavioural and microdialysis study in ratsWATANABE, Chizuko; OKUDA, Kazuhiro; SAKURADA, Chikai et al.Brain research. 2003, Vol 990, Num 1-2, pp 77-86, issn 0006-8993, 10 p.Article

Differential effects of intraplantar capsazepine and ruthenium red on capsaicin-induced desensitization in miceSAKURADA, Tsukasa; MATSUMURA, Toshihiro; MORIYAMA, Tomoko et al.Pharmacology, biochemistry and behavior. 2003, Vol 75, Num 1, pp 115-121, issn 0091-3057, 7 p.Article

Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo studySAKURADA, Chikai; SAKURADA, Shinobu; ORITO, Tohru et al.Biochemical pharmacology. 2002, Vol 64, Num 8, pp 1293-1303, issn 0006-2952, 11 p.Article

The role of spinal nitric oxide and glutamate in nociceptive behaviour evoked by high-dose intrathecal morphine in ratsWATANABE, Chizuko; SAKURADA, Tsukasa; OKUDA, Kazuhiro et al.Pain (Amsterdam). 2003, Vol 106, Num 3, pp 269-283, issn 0304-3959, 15 p.Article

Intraplantar injection of bergamot essential oil induces peripheral antinociception mediated by opioid mechanismSAKURADA, Tsukasa; MIZOGUCHI, Hirokazu; KUWAHATA, Hikari et al.Pharmacology, biochemistry and behavior. 2011, Vol 97, Num 3, pp 436-443, issn 0091-3057, 8 p.Article

Involvement of spinal μ₁-opioid receptors on the Tyr-D-Arg-Phe-sarcosine-induced antinociceptionMIZOGUCHI, Hirokazu; NAKAYAMA, Daisuke; WATANABE, Hiroyuki et al.European journal of pharmacology. 2006, Vol 540, Num 1-3, pp 67-72, issn 0014-2999, 6 p.Article

Partial involvement of NMDA receptors and glial cells in the nociceptive behaviors induced by intrathecally administered histamineMIZOGUCHI, Hirokazu; KOMATSU, Takaaki; SAKURADA, Shinobu et al.Neuroscience letters. 2011, Vol 495, Num 2, pp 83-87, issn 0304-3940, 5 p.Article

Possible involvement of dynorphin A release via μ₁-opioid receptor on supraspinal antinociception of endomorphin-2SAKURADA, Shinobu; SAWAI, Toshiki; MIZOGUCHI, Hirokazu et al.Peptides (New York, NY. 1980). 2008, Vol 29, Num 9, pp 1554-1560, issn 0196-9781, 7 p.Article

Involvement of P2X₂ and P2X₃ receptors in neuropathic pain in a mouse model of chronic constriction injuryUENO, Shinya; MORIYAMA, Tomoko; HONDA, Kenji et al.Drug development research. 2003, Vol 59, Num 1, pp 104-111, issn 0272-4391, 8 p.Conference Paper

Antinociceptive effect of spinally injected L-NAME on the acute nociceptive response induced by low concentrations of formalinSAKURADA, Chikai; SUGIYAMA, Akinori; NAKAYAMA, Miho et al.Neurochemistry international. 2001, Vol 38, Num 5, pp 417-423, issn 0197-0186Article

Lack of a rewarding effect and a locomotor-enhancing effect of the selective μ-opioid receptor agonist amidino-TAPAMIZOGUCHI, Hirokazu; WATANABE, Chizuko; SAKURADA, Shinobu et al.Psychopharmacologia. 2010, Vol 212, Num 2, pp 215-225, issn 0033-3158, 11 p.Article

Effects of intraplantar injections of nociceptin and its N-terminal fragments on nociceptive and desensitized responses induced by capsaicin in miceSAKURADA, Tsukasa; KOMATSU, Takaaki; MORIYAMA, Tomoko et al.Peptides (New York, NY. 1980). 2005, Vol 26, Num 12, pp 2505-2512, issn 0196-9781, 8 p.Article

Differential involvement of μ₁-opioid receptors in dermorphin tetrapeptide analogues-induced antinociceptionMIZOGUCHI, Hirokazu; YUHKI, Masayuki; WATANABE, Hiroyuki et al.European journal of pharmacology. 2004, Vol 486, Num 1, pp 19-24, issn 0014-2999, 6 p.Article

Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanismTAN-NO, Koichi; ESASHI, Akihisa; NAKAGAWASAI, Osamu et al.Brain research. 2002, Vol 952, Num 1, pp 7-14, issn 0006-8993Article

Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouseSAKURADA, Shinobu; HAYASHI, Takafumi; NARITA, Minoru et al.European journal of pharmacology. 2001, Vol 427, Num 3, pp 203-210, issn 0014-2999Article

Involvement of glial cells in the nociceptive behaviors induced by a high-dose of histamine administered intrathecallyMIZOGUCHI, Hirokazu; KOMATSU, Takaaki; SAKURADA, Shinobu et al.European journal of pharmacology. 2011, Vol 653, Num 1-3, pp 21-25, issn 0014-2999, 5 p.Article

Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascadeSAKURADA, Tsukasa; KOMATSU, Takaaki; KUWAHATA, Hikari et al.Biochemical pharmacology. 2007, Vol 74, Num 5, pp 758-767, issn 0006-2952, 10 p.Article

Contribution of spinal μ₁-opioid receptors and dynorphin B to the antinociception induced by Tyr-D-Arg-Phe-SarMIZOGUCHI, Hirokazu; ITO, Kanenori; WATANABE, Hiroyuki et al.Peptides (New York, NY. 1980). 2006, Vol 27, Num 11, pp 2786-2793, issn 0196-9781, 8 p.Article