Mass balance studies, with a focus on anticancer drugsBEUMER, Jan H; BEIJNEN, Jos H; SCHELLENS, Jan H. M et al.Clinical pharmacokinetics. 2006, Vol 45, Num 1, pp 33-58, issn 0312-5963, 26 p.Article

Simultaneous determination of AZD1152 (prodrug) and AZD1152-hydroxyquinazoline pyrazol anilide by reversed phase liquid chromatographyPLUIM, Dick; BEIJNEN, Jos H; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2009, Vol 877, Num 29, pp 3549-3555, issn 1570-0232, 7 p.Article

Enzymatic digestion as a tool for the LC-MS/MS quantification of large peptides in biological matrices : Measurement of chymotryptic fragments from the HIV-1 fusion inhibitor enfuvirtide and its metabolite M-20 in human plasmaVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2007, Vol 854, Num 1-2, pp 245-259, issn 1570-0232, 15 p.Article

The effect of hydroxyurea on P-glycoprotein/BCRP-mediated transport and CYP3A metabolism of imatinib mesylateOOSTENDORP, Roos L; MARCHETTI, Serena; BEIJNEN, Jos H et al.Cancer chemotherapy and pharmacology. 2007, Vol 59, Num 6, pp 855-860, issn 0344-5704, 6 p.Article

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasmaSCHOEMAKER, Nadja E; ROSING, Hilde; JANSEN, Sindy et al.Therapeutic drug monitoring. 2003, Vol 25, Num 1, pp 120-124, issn 0163-4356, 5 p.Article

Oral delivery of taxanesMALINGRE, Mirte M; BEIJNEN, Jos H; SCHELLENS, Jan H. M et al.Investigational new drugs. 2001, Vol 19, Num 2, pp 155-162, issn 0167-6997Article

Population Pharmacokinetics and Pharmacodynamics for Treatment Optimization in Clinical OncologyZANDVLIET, Anthe S; SCHELLENS, Jan H. M; BEIJNEN, Jos H et al.Clinical pharmacokinetics. 2008, Vol 47, Num 8, pp 487-513, issn 0312-5963, 27 p.Article

Absence of N-linked glycosylation does not affect plasma membrane localization of breast cancer resistance protein (BCRP/ABCG2)MOHRMANN, Karin; VAN EIJNDHOVEN, Maria A. J; SCHINKEL, Alfred H et al.Cancer chemotherapy and pharmacology. 2005, Vol 56, Num 4, pp 344-350, issn 0344-5704, 7 p.Article

The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteersGOEY, Andrew K. L; MEIJERMAN, Irma; BEIJNEN, Jos H et al.European journal of clinical pharmacology. 2013, Vol 69, Num 11, pp 1883-1890, issn 0031-6970, 8 p.Article

Evaluation of Oncology Drugs at the European Medicines Agency and US Food and Drug Administration: When Differences Have an Impact on Clinical PracticeTROTTA, Francesco; LEUFKENS, Hubert G. M; SCHELLENS, Jan H. M et al.Journal of clinical oncology. 2011, Vol 29, Num 16, pp 2266-2272, issn 0732-183X, 7 p.Article

Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometryVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2010, Vol 878, Num 5-6, pp 590-602, issn 1570-0232, 13 p.Article

Validation of a quantitative assay for human neutrophil peptide-1, -2, and -3 in human plasma and serum by liquid chromatography coupled to tandem mass spectrometryVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2010, Vol 878, Num 15-16, pp 1085-1092, issn 1570-0232, 8 p.Article

Protein versus DNA as a marker for peripheral blood mononuclear cell countingJANSEN, Robert S; ROSING, Hilde; SCHELLENS, Jan H. M et al.Analytical & bioanalytical chemistry (Print). 2009, Vol 395, Num 3, pp 863-867, issn 1618-2642, 5 p.Article

Liquid chromatographic assay for the antiviral nucleotide analogue tenofovir in plasma using derivatization with chloroacetaldehydeSPARIDANS, Rolf W; CROMMENTUYN, Kristel M. L; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2003, Vol 791, Num 1-2, pp 227-233, issn 1570-0232, 7 p.Article

MASS SPECTROMETRY IN THE QUANTITATIVE ANALYSIS OF THERAPEUTIC INTRACELLULAR NUCLEOTIDE ANALOGSJANSEN, Robert S; ROSING, Hilde; SCHELLENS, Jan H. M et al.Mass spectrometry reviews (Print). 2011, Vol 30, Num 2, pp 321-343, issn 0277-7037, 23 p.Article

Clinical proteomics in breast cancer: a reviewGAST, Marie-Christine W; SCHELLENS, Jan H. M; BEIJNEN, Jos H et al.Breast cancer research and treatment. 2009, Vol 116, Num 1, pp 17-29, issn 0167-6806, 13 p.Article

Retention studies of 2'-2'-difluorodeoxycytidine and 2'-2'-difluorodeoxyuridine nucleosides and nucleotides on porous graphitic carbon : Development of a liquid chromatography-tandem mass spectrometry methodJANSEN, Robert S; ROSING, Hilde; SCHELLENS, Jan H. M et al.Journal of chromatography. 2009, Vol 1216, Num 15, pp 3168-3174, issn 0021-9673, 7 p.Article

Quantitative aspects of the analysis of the monoclonal antibody trastuzumab using high-performance liquid chromatography coupled with electrospray mass spectrometryDAMEN, Carola W. N; ROSING, Hilde; SCHELLENS, Jan H. M et al.Journal of pharmaceutical and biomedical analysis. 2008, Vol 46, Num 3, pp 449-455, issn 0731-7085, 7 p.Article

Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometryVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2008, Vol 872, Num 1-2, pp 1-22, issn 1570-0232, 22 p.Article

Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for ImprovementSTUURMAN, Frederik E; NUIJEN, Bastiaan; BEIJNEN, Jos H et al.Clinical pharmacokinetics. 2013, Vol 52, Num 6, pp 399-414, issn 0312-5963, 16 p.Article

Clinical Pharmacokinetics of Therapeutic Monoclonal AntibodiesKEIZER, Ron J; HUITEMA, Alwin D. R; SCHELLENS, Jan H. M et al.Clinical pharmacokinetics. 2010, Vol 49, Num 8, pp 493-507, issn 0312-5963, 15 p.Article

Application of dried blood spots combined with high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry for simultaneous quantification of vincristine and actinomycin-D : Trends in RNA AnalysisDAMEN, Carola W. N; ROSING, Hilde; SCHELLENS, Jan H. M et al.Analytical & bioanalytical chemistry (Print). 2009, Vol 394, Num 4, pp 1171-1182, issn 1618-2642, 12 p.Article

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancerBOSCH, Tessa M; MEIJERMAN, Irma; BEIJNEN, Jos H et al.Clinical pharmacokinetics. 2006, Vol 45, Num 3, pp 253-285, issn 0312-5963, 33 p.Article

Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detectionSTOKVIS, Ellen; ROSING, Hilde; CAUSON, Roger C et al.Journal of mass spectrometry. 2004, Vol 39, Num 10, pp 1122-1130, issn 1076-5174, 9 p.Article

Isocratic ion-exchange chromatographic assay for the nucleotide gemcitabine triphosphate in human white blood cellsSPARIDANS, Rolf W; CRUL, Mirjam; SCHELLENS, Jan H. M et al.Journal of chromatography. B, Biomedical sciences and applications. 2002, Vol 780, Num 2, pp 423-430, issn 1387-2273, 8 p.Article