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Results 1 to 25 of 58

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High-potency human immunodeficiency virus vaccination leads to delayed and reduced CD8+ T-cell expansion but improved virus controlDAVENPORT, Miles P; LEI ZHANG; BAGCHI, Ansuman et al.Journal of virology. 2005, Vol 79, Num 15, pp 10059-10062, issn 0022-538X, 4 p.Article

Residual human immunodeficiency virus (HIV) type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 yearsGÜNTHARD, Huldrych F; HAVLIR, Diane V; VALENTINE, Fred et al.The Journal of infectious diseases. 2001, Vol 183, Num 9, pp 1318-1327, issn 0022-1899Article

Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integraseMELAMED, Jeffrey Y; EGBERTSON, Melissa S; HAZUDA, Daria J et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 19, pp 5307-5310, issn 0960-894X, 4 p.Article

Characterization of gp120 and its single-chain derivatives, gp120-CD4D12 and gp120-M9: Implications for targeting the CD4i epitope in human immunodeficiency virus vaccine designVARADARAJAN, Raghavan; SHARMA, Deepak; GELEZIUNAS, Romas et al.Journal of virology. 2005, Vol 79, Num 3, pp 1713-1723, issn 0022-538X, 11 p.Article

A potent and orally active HIV-1 integrase inhibitorEGBERTSON, Melissa S; MORITZ, H. Marie; WALLACE, Audrey et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 5, pp 1392-1398, issn 0960-894X, 7 p.Article

Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assayOPALKA, David; PESSI, Antonello; BRAMHILL, David et al.Journal of immunological methods. 2004, Vol 287, Num 1-2, pp 49-65, issn 0022-1759, 17 p.Article

Chemistry and structure-activity relationship of HIV-1 integrase inhibitor integracide B and related natural productsSINGH, Sheo B; ONDEYKA, John G; SCHLEIF, William A et al.Journal of natural products (Print). 2003, Vol 66, Num 10, pp 1338-1344, issn 0163-3864, 7 p.Article

Drug resistance and predicted virologic responses to human immunodeficiency virus type 1 protease inhibitor therapyCONDRA, Jon H; PETROPOULOS, Christos J; ZIERMANN, Rainer et al.The Journal of infectious diseases. 2000, Vol 182, Num 3, pp 758-765, issn 0022-1899Article

Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virusRAGHAVAN, Subharekha; ZHIJIAN LU; TATA, James R et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 19, pp 5432-5436, issn 0960-894X, 5 p.Article

P1' oxadiazole protease inhibitors with excellent activity against native and protease inhibitor-resistant HIV-1KIM, Ronald M; ROUSE, Elizabeth A; CHAPMAN, Kevin T et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 18, pp 4651-4654, issn 0960-894X, 4 p.Article

The design, synthesis and evaluation of novel HIV-1 protease inhibitors with high potency against PI-resistant viral strainsZHANG, Fengqi; CHAPMAN, Kevin T; TATA, James R et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 15, pp 2573-2576, issn 0960-894X, 4 p.Article

Combinatorial library of indinavir analogues: Replacement for the aminoindanol at P2'RAGHAVAN, Subharekha; ZHENG YANG; TATA, James R et al.Bioorganic & medicinal chemistry letters (Print). 2002, Vol 12, Num 20, pp 2855-2858, issn 0960-894X, 4 p.Article

Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitorsLANGFORD, H. Marie; WILLIAMS, Peter D; HOMNICK, Carl F et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 2, pp 721-725, issn 0960-894X, 5 p.Article

8 -Hydroxy -3,4 -dihydropyrrolo[1,2 -a]pyrazine -1 (2H) -one HIV-1 integrase inhibitorsFISHER, Thorsten E; KIM, Boyoung; GABRYELSKI, Lori J et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 23, pp 6511-6515, issn 0960-894X, 5 p.Article

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitorsSMITH, Amos B; CANTIN, Louis-David; OLSEN, David B et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 10, pp 1831-1844, issn 0022-2623, 14 p.Article

Novel HIV-1 protease inhibitors active against multiple PI-resistant viral strains: Coadministration with indinavirKEVIN, Nancy J; DUFFY, Joseph L; LIN, Jiunn H et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 22, pp 4027-4030, issn 0960-894X, 4 p.Article

Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-resistant viral strainsYUAN CHENG; FENGQI ZHANG; LIXIA JIN et al.Bioorganic & medicinal chemistry letters (Print). 2002, Vol 12, Num 17, pp 2419-2422, issn 0960-894XArticle

Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virusZHIJIAN LU; BOHN, Joann; LIN, Jiunn H et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 23, pp 5311-5314, issn 0960-894X, 4 p.Article

Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virusZHIJIAN LU; RAGHAVAN, Subharekha; GABRYELSKI, Lori et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 10, pp 1821-1824, issn 0960-894X, 4 p.Article

HIV protease inhibitors with picomolar potency against PI-resistant HIV-1 by extension of the P3 substituentDULLY, Joseph L; RANO, Thomas A; LIN, Jiunn H et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 15, pp 2569-2572, issn 0960-894X, 4 p.Article

Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogsBERA, Sanjib; MALIK, Leila; SCHLEIF, William A et al.Bioorganic & medicinal chemistry. 2004, Vol 12, Num 23, pp 6237-6247, issn 0968-0896, 11 p.Article

HIV-1 protease inhibitors with picomolar potency against pi-resistant HIV-1 by modification of the P1' substituentDUFFY, Joseph L; KIRK, Brian A; LIN, Jiunn H et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 19, pp 3323-3326, issn 0960-894X, 4 p.Article

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chainsSMITH, Amos B; CHARNLEY, Adam K; SCHLEIF, William A et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 4, pp 859-863, issn 0960-894X, 5 p.Article

Synthesis and activity of novel HIV protease inhibitors with improved potency against multiple PI-resistant viral strainsDUFFY, Joseph L; KEVIN, Nancy J; LIN, Jiunn H et al.Bioorganic & medicinal chemistry letters (Print). 2002, Vol 12, Num 17, pp 2423-2426, issn 0960-894XArticle

Efficacy of indinavir-ritonavir-based regimens in HIV-1-infected patients with prior protease inhibitor failuresCAMPO, Rafael E; MORENO, Jose N; EMINI, Emilio A et al.AIDS (London). 2003, Vol 17, Num 13, pp 1933-1939, issn 0269-9370, 7 p.Article

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