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A ligand-based approach to understanding selectivity of nuclear hormone receptors PXR, CAR, FXR, LXRα, and LXRβEKINS, Sean; MIRNY, Leonid; SCHUETZ, Erin G et al.Pharmaceutical research. 2002, Vol 19, Num 12, pp 1788-1800, issn 0724-8741, 13 p.Article

Genetic contribution to variable human CYP3A-mediated metabolismLAMBA, Jatinder K; LIN, Yvonne S; SCHUETZ, Erin G et al.Advanced drug delivery reviews. 2012, Vol 64, pp 256-269, issn 0169-409X, 14 p., SUPArticle

Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyreneKALABUS, James L; QIUYING CHENG; JAMIL, Raqeeb G et al.Toxicology letters. 2012, Vol 211, Num 3, pp 266-273, issn 0378-4274, 8 p.Article

PharmGKB summary: very important pharmacogene information for CYP3A5LAMBA, Jatinder; HEBERT, Joan M; SCHUETZ, Erin G et al.Pharmacogenetics and genomics (Print). 2012, Vol 22, Num 7, pp 555-558, issn 1744-6872, 4 p.Article

Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytesRAMIREZ, Jacqueline; KOMOROSKI, Bernard J; MIRKOV, Snezana et al.Pharmacogenetics and genomics (Print). 2006, Vol 16, Num 2, pp 79-86, issn 1744-6872, 8 p.Article

Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivoLECUREUR, Valerie; THOTTASSERY, Jaideep V; DAXI SUN et al.Oncogene (Basingstoke). 2001, Vol 20, Num 3, pp 303-313, issn 0950-9232Article

A Phosphomimetic Mutation at Threonine-57 Abolishes Transactivation Activity and Alters Nuclear Localization Pattern of Human Pregnane X ReceptorPONDUGULA, Satyanarayana R; BRIMER-CLINE, Cynthia; JING WU et al.Drug metabolism and disposition. 2009, Vol 37, Num 4, pp 719-730, issn 0090-9556, 12 p.Article

Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicityWOLF, Kristina K; WOOD, Sheryl G; EVANS, Ronald M et al.Drug metabolism and disposition. 2005, Vol 33, Num 12, pp 1827-1836, issn 0090-9556, 10 p.Article

Nonsense mediated decay downregulates conserved alternatively spliced ABCC4 transcripts bearing nonsense codonsJATINDER KAUR LAMBA; ADACHI, Masashi; DAXI SUN et al.Human molecular genetics (Print). 2003, Vol 12, Num 2, pp 99-109, issn 0964-6906, 11 p.Article

The Influence of CYP3A5 Genotype on Dexamethasone Induction of CYP3A Activity in African AmericansROBERTS, Patrick J; ROLLINS, Kristan D; KASHUBA, Angela D. M et al.Drug metabolism and disposition. 2008, Vol 36, Num 8, pp 1465-1469, issn 0090-9556, 5 p.Article

Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestineZAMBER, Charis P; LAMBA, Jatinder K; YASUDA, Kazuto et al.Pharmacogenetics (London). 2003, Vol 13, Num 1, pp 19-28, issn 0960-314X, 10 p.Article

Common allelic variants of cytochrome P4503A4 and their prevalence in different populationsLAMBA, Jatinder K; LIN, Yvonne S; THUMMEL, Kenneth et al.Pharmacogenetics (London). 2002, Vol 12, Num 2, pp 121-132, issn 0960-314XArticle

The human CYP3A subfamily : Practical considerationsWRIGHTON, Steven A; SCHUETZ, Erin G; THUMMEL, Kenneth E et al.Drug metabolism reviews (Softcover ed.). 2000, Vol 32, Num 3-4, pp 339-361, issn 0360-2532Conference Paper

Hepatic Organic Anion Transporting Polypeptide Transporter and Thyroid Hormone Receptor Interplay Determines Cholesterol and Glucose HomeostasisMEYER ZU SCHWABEDISSEN, Henriette E; WARE, Joseph A; SCHUETZ, Erin G et al.Hepatology (Baltimore, Md.). 2011, Vol 54, Num 2, pp 644-654, issn 0270-9139, 11 p.Article

Liver X Receptor α and Farnesoid X Receptor Are Major Transcriptional Regulators of OATP1B1MEYER ZU SCHWABEDISSEN, Henriette E; BÖTTCHER, Kerstin; CHAUDHRY, Amarjit et al.Hepatology (Baltimore, Md.). 2010, Vol 52, Num 5, pp 1797-1807, issn 0270-9139, 11 p.Article

Induction of CYP3A4 by Vinblastine: Role of the Nuclear Receptor NR112SMITH, Nicola F; MANI, Sridhar; SCHUETZ, Erin G et al.The Annals of pharmacotherapy. 2010, Vol 44, Num 11, pp 1709-1717, issn 1060-0280, 9 p.Article

Structural determinants of P-glycoprotein-mediated transport of glucocorticoidsYATES, Charles R; CHENG CHANG; KEARBEY, Jeffrey D et al.Pharmaceutical research. 2003, Vol 20, Num 11, pp 1794-1803, issn 0724-8741, 10 p.Article

The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemiaVAN DE POLL, Matthijs E. C; RELLING, Mary V; SCHUETZ, Erin G et al.Cancer chemotherapy and pharmacology. 2001, Vol 47, Num 6, pp 467-472, issn 0344-5704Article

Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1WANG, Yue-Ming; WENWEI LIN; CHAI, Sergio C et al.Toxicology and applied pharmacology. 2013, Vol 272, Num 1, pp 96-107, issn 0041-008X, 12 p.Article

The Major Human Pregnane X Receptor (PXR) Splice Variant, PXR.2, Exhibits Significantly Diminished Ligand-Activated Transcriptional RegulationLIN, Yvonne S; YASUDA, Kazuto; EKINS, Sean et al.Drug metabolism and disposition. 2009, Vol 37, Num 6, pp 1295-1304, issn 0090-9556, 10 p.Article

Expression of the pregnane X receptor in mice antagonizes the cholic acid-mediated changes in plasma lipoprotein profileMASSON, David; LAGROST, Laurent; ATHIAS, Anne et al.Arteriosclerosis, thrombosis, and vascular biology. 2005, Vol 25, Num 10, pp 2164-2169, issn 1079-5642, 6 p.Article

Cisapride: A potential model substrate to assess cytochrome P4503A4 activity in vivoLOWRY, Jennifer A; KEARNS, Gregory L; ABDEL-RAHMAN, Susan M et al.Clinical pharmacology and therapeutics. 2003, Vol 73, Num 3, pp 209-222, issn 0009-9236, 14 p.Article

Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitorsHEBERT, Mary F; DOWLING, Amy L. S; GIERWATOWSKI, Cynthia et al.Pharmacogenetics (London). 2003, Vol 13, Num 11, pp 661-674, issn 0960-314X, 14 p.Article

Identification of functionally variant MDR1 alleles among European Americans and African AmericansKIM, Richard B; LEAKE, Brenda F; LAN, Lu-Bin et al.Clinical pharmacology and therapeutics. 2001, Vol 70, Num 2, pp 189-199, issn 0009-9236Article

Ontogeny and Sorafenib MetabolismZIMMERMAN, Eric I; ROBERTS, Justin L; LIE LI et al.Clinical cancer research (Print). 2012, Vol 18, Num 20, pp 5788-5795, issn 1078-0432, 8 p.Article

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