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Toward a unified theory of caloric restriction and longevity regulationSINCLAIR, David A.Mechanisms of ageing and development. 2005, Vol 126, Num 9, pp 987-1002, issn 0047-6374, 16 p.Article

The Intersection Between Aging and Cardiovascular DiseaseNORTH, Brian J; SINCLAIR, David A.Circulation research. 2012, Vol 110, Num 8, pp 1097-1108, issn 0009-7330, 12 p.Article

Longevity regulation in Saccharomyces cerevisiae: Linking metabolism, genome stability, and heterochromatinBITTERMAN, Kevin J; MEDVEDIK, Oliver; SINCLAIR, David A et al.Microbiology and molecular biology reviews. 2003, Vol 67, Num 3, issn 1092-2172, 301, 376-399 [25 p.]Article

Flavonoid Apigenin Is an Inhibitor of the NAD⁺ase CD38: Implications for Cellular NAD⁺ Metabolism, Protein Acetylation, and Treatment of Metabolic SyndromeESCANDE, Carlos; NIN, Veronica; PRICE, Nathan L et al.Diabetes (New York, NY). 2013, Vol 62, Num 4, pp 1084-1093, issn 0012-1797, 10 p.Article

HST2 mediates SIR2-independent life-span extension by calorie restrictionLAMMING, Dudley W; LATORRE-ESTEVES, Magda; MEDVEDIK, Oliver et al.Science (Washington, D.C.). 2005, Vol 309, Num 5742, pp 1861-1864, issn 0036-8075, 4 p.Article

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylaseBRUNET, Anne; SWEENEY, Lora B; HU, Linda S et al.Science (Washington, D.C.). 2004, Vol 303, Num 5666, pp 2011-2015, issn 0036-8075, 5 p.Article

Biological stress response terminology : Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response frameworkCALABRESE, Edward J; BACHMANN, Kenneth A; COOK, Ralph R et al.Toxicology and applied pharmacology. 2007, Vol 222, Num 1, pp 122-128, issn 0041-008X, 7 p.Article

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanHOWLTZ, Konrad T; BITTERMAN, Kevin J; SCHERER, Brandy et al.Nature (London). 2003, Vol 425, Num 6954, pp 191-196, issn 0028-0836, 6 p.Article

Yeast life-span extension by calorie restriction is independent of NAD fluctuationANDERSON, Rozalyn M; LATORRE-ESTEVES, Magda; NEVES, Ana Rute et al.Science (Washington, D.C.). 2003, Vol 302, Num 5653, pp 2124-2126, issn 0036-8075, 3 p.Article

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetesMILNE, Jill C; LAMBERT, Philip D; BEMIS, Jean E et al.Nature (London). 2007, Vol 450, Num 7170, pp 712-716, issn 0028-0836, 5 p.Article

Type 5 Adenylyl Cyclase Increases Oxidative Stress by Transcriptional Regulation of Manganese Superoxide Dismutase via the SIRT1/FoxO3a PathwayLO LAI; LIN YAN; AUWERX, Johan et al.Circulation (New York, N.Y.). 2013, Vol 127, Num 16, pp 1692-1701, issn 0009-7322, 10 p.Article

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 * deacetylaseCOHEN, Haim Y; MILLER, Christine; BITTERMAN, Kevin J et al.Science (Washington, D.C.). 2004, Vol 305, Num 5682, pp 390-392, issn 0036-8075, 3 p.Article

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiaeANDERSON, Rozalyn M; BITTERMAN, Kevin J; WOOD, Jason G et al.Nature (London). 2003, Vol 423, Num 6936, pp 181-185, issn 0028-0836, 5 p.Article

SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin SensitivityRUTANEN, Jarno; YALURI, Nagendra; ELLIOTT, Peter et al.Diabetes (New York, NY). 2010, Vol 59, Num 4, pp 829-835, issn 0012-1797, 7 p.Article

Resveratrol improves health and survival of mice on a high-calorie dietBAUR, Joseph A; PEARSON, Kevin J; PISTELL, Paul J et al.Nature (London). 2006, Vol 444, Num 7117, pp 337-342, issn 0028-0836, 6 p.Article

Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (sirtuin) inhibitorsMAI, Antonello; MASSA, Silvio; LAVU, Siva et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 24, pp 7789-7795, issn 0022-2623, 7 p.Article

Small molecules that regulate lifespan: evidence for xenohormesisLAMMING, Dudley W; WOOD, Jason G; SINCLAIR, David A et al.Molecular microbiology (Print). 2004, Vol 53, Num 4, pp 1003-1009, issn 0950-382X, 7 p.Article