Distorted amides as models for activated peptide N―C=O units produced during enzyme-catalyzed acyl transfer reactions. I: The mechanism of hydrolysis of 3,4-dihydro-2-oxo-1,4-ethanoquinoline and 2,3,4,5-tetrahydro-2-oxo-1,5-ethanobenzazepineSOMAYAJI, V; BROWN, R. S.Journal of organic chemistry. 1986, Vol 51, Num 14, pp 2676-2686, issn 0022-3263Article

Hydrolysis of a distorted amide facilitated by diacids: a phenomenological model for the aspartate proteinasesSOMAYAJI, V; BROWN, R. S.Journal of the American Chemical Society. 1987, Vol 109, Num 15, pp 4738-4739, issn 0002-7863Article

Convenient procedure for the synthesis of (E)-1-bromo-1-alkenes and (Z)-1-iodo-1-alkenesBROWN, H. C; SOMAYAJI, V.Synthesis (Stuttgart). 1984, Vol 11, pp 919-920, issn 0039-7881Article

Direct O-acylation of small molecules containing CO₂^--HN←HO units by a distorted amide: enhancement of amine basicity bt a pendant carboxylate in a serine protease mimicSKOREY, K. I; SOMAYAJI, V; BROWN, R. S et al.Journal of the American Chemical Society. 1989, Vol 111, Num 4, pp 1445-1452, issn 0002-7863, 8 p.Article

Organoboranes. XXX: Convenient procedures for the synthesis of alkyl- and alkenylboronic acids and estersBROWN, H. C; BHAT, N. G; SOMAYAJI, V et al.Organometallics. 1983, Vol 2, Num 10, pp 1311-1316, issn 0276-7333Article

The influence of a carboxylate group on the rate of O-acylation of 2-hydroxymethylimidazoles by a strained amideSKOREY, K. I; SOMAYAJI, V; BROWN, R. S et al.Journal of the American Chemical Society. 1988, Vol 110, Num 15, pp 5205-5206, issn 0002-7863Article

Hydroboration. LXIX: Hydroboration characteristics of lithium borohydride/ethyl acetate in ethyl ether. A new system for controlled hydroboration of alkenes and alkynesBROWN, H. C; SOMAYAJI, V; NARASIMHAN, S et al.Journal of organic chemistry. 1984, Vol 49, Num 25, pp 4822-4827, issn 0022-3263Article

Hydroboration. LXIX: Hydroboration characteristics of lithium borohydride/ethyl acetate in ethyl ether. A new system for controlled hydroboration of alkenes and alkynesBROWN, H. C; SOMAYAJI, V; NARASIMHAN, S et al.Journal of organic chemistry. 1984, Vol 49, Num 25, pp 4822-4827, issn 0022-3263Article

Model for the aspartate proteinases: hydrolysis of a distorted amide catalyzed by dicarboxylic acids capable of forming cyclic anhydridesSOMAYAJI, V; KEILLOR, J; BROWN, R. S et al.Journal of the American Chemical Society. 1988, Vol 110, Num 8, pp 2625-2629, issn 0002-7863Article

The influence of altered amidic resonance on the infrared and ¹³C and ¹⁵N NMR spectroscopic characteristics and barriers to rotation about the N-C(O) bond in some anilides and toluamidesBENNET, A. J; SOMAYAJI, V; BROWN, R. S et al.Journal of the American Chemical Society. 1991, Vol 113, Num 20, pp 7563-7571, issn 0002-7863Article

Relationship between amidic distortion and ease of hydrolysis in base. If amidic resonance does not exist, then what accounts for the accelerated hydrolysis of distorted amides?BENNET, A. J; QING-PING WANG; SLEBOCKA-TILK, H et al.Journal of the American Chemical Society. 1990, Vol 112, Num 17, pp 6383-6385, issn 0002-7863, 3 p.Article

A Dose-Ranging Study of the DPP-IV Inhibitor PF-734200 Added to Metformin in Subjects With Type 2 DiabetesTERRA, S. G; SOMAYAJI, V; SCHWARTZ, S et al.Experimental and clinical endocrinology & diabetes. 2011, Vol 119, Num 7, pp 401-407, issn 0947-7349, 7 p.Article

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor PF-734200 added to metformin in Type 2 diabetesROSENSTOCK, J; LEWINT, A. J; NORWOOD, P et al.Diabetic medicine. 2011, Vol 28, Num 4, pp 464-469, issn 0742-3071, 6 p.Article

Molecular structure of 2,3,4,5-tetrahydro-2-oxo-1,5-ethanobenzazepine and its reaction with β-amino alcohols as a model for the acylation step of the serine proteasesSOMAYAJI, V; SKOREY, K. I; BROWN, R. S et al.Journal of organic chemistry. 1986, Vol 51, Num 25, pp 4866-4872, issn 0022-3263Article

Preparation and protein conjugation of a divinyl sulphone derivatized bifunctional chelating agentSOMAYAJI, V. V; NAICKER, S. S; SYKES, T. R et al.Cancer biotherapy & radiopharmaceuticals. 1996, Vol 11, Num 6, pp 405-414, issn 1084-9785Article

Radioiodinated 1-(2-fluoro-4-iodo-2,4-dideoxy-β-L-xylopyranosyl)-2- nitroimidazole : a novel probe for the noninvasive assessment of tumor hypoxiaMANNAN, R. H; MERCER, J. R; WIEBE, L. I et al.Radiation research. 1992, Vol 132, Num 3, pp 368-374, issn 0033-7587Article

Radioiodinated 1-5-iodo-5-deoxy-β-D-arabinofuranosyl-2-nitroimidazole (iodoazomycin arabinoside : IAZA) : a novel marker of tissue hypoxiaMANNAN, R. H; SOMAYAJI, V. V; LEE, J et al.JNM. Journal of nuclear medicine (The) : (1990). 1991, Vol 32, Num 9, pp 1764-1770Article