Role of oxidative stress in cardiac hypertrophy and remodelingTAKIMOTO, Eiki; KASS, David A.Hypertension (Dallas, Tex. 1979). 2007, Vol 49, Num 2, pp 241-248, issn 0194-911X, 8 p.Article

Modulation of in vivo cardiac function by myocyte-specific nitric oxide synthase-3CHAMPION, Hunter C; GEORGAKOPOULOS, Dimitrios; TAKIMOTO, Eiki et al.Circulation research. 2004, Vol 94, Num 5, pp 657-663, issn 0009-7330, 7 p.Article

Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sitesTAKIMOTO, Eiki; SOERGEL, David G; JANSSEN, Paul M. L et al.Circulation research. 2004, Vol 94, Num 4, pp 496-504, issn 0009-7330, 9 p.Article

Reversal of Cardiac Hypertrophy and Fibrosis From Pressure Overload by Tetrahydrobiopterin : Efficacy of Recoupling Nitric Oxide Synthase as a Therapeutic StrategyMOENS, An L; TAKIMOTO, Eiki; MITCHELL, James B et al.Circulation (New York, N.Y.). 2008, Vol 117, Num 20, pp 2626-2636, issn 0009-7322, 11 p.Article

Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophyYUNZENG ZOU; HIROI, Yukio; NAGAI, Ryozo et al.Circulation (New York, N.Y.). 2001, Vol 104, Num 1, pp 97-101, issn 0009-7322Article

Compartmentalization of cardiac β-adrenergic inotropy modulation by phosphodiesterase type 5TAKIMOTO, Eiki; BELARDI, Diego; TOCCHETTI, Carlo G et al.Circulation (New York, N.Y.). 2007, Vol 115, Num 16, pp 2159-2167, issn 0009-7322, 9 p.Article

cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanismTAKIMOTO, Eiki; CHAMPION, Hunter C; DOSTMANN, Wolfgang R et al.Circulation research. 2005, Vol 96, Num 1, pp 100-109, issn 0009-7330, 10 p.Article

Pathological Cardiac Hypertrophy Alters Intracellular Targeting of Phosphodiesterase Type 5 From Nitric Oxide Synthase-3 to Natriuretic Peptide SignalingMANLING ZHANG; TAKIMOTO, Eiki; EATON, Philip et al.Circulation (New York, N.Y.). 2012, Vol 126, Num 8, pp 942-951, issn 0009-7322, 10 p.Article

Myocardial Remodeling Is Controlled by Myocyte-Targeted Gene Regulation of Phosphodiesterase Type 5MANLING ZHANG; TAKIMOTO, Eiki; YIBIN WANG et al.Journal of the American College of Cardiology. 2010, Vol 56, Num 24, pp 2021-2030, issn 0735-1097, 10 p.Article

Sildenafil Stops Progressive Chamber, Cellular, and Molecular Remodeling and Improves Calcium Handling and Function in Hearts With Pre-Existing Advanced Hypertrophy Caused by Pressure OverloadNAGAYAMA, Takahiro; HSU, Steven; MANLING ZHANG et al.Journal of the American College of Cardiology. 2009, Vol 53, Num 2, pp 207-217, issn 0735-1097, 11 p.Article

Pressure-Overload-Induced Subcellular Relocalization/Oxidation of Soluble Guanylyl Cyclase in the Heart Modulates Enzyme StimulationTSAI, Emily J; YUCHUAN LIU; KOITABASHI, Norimichi et al.Circulation research. 2012, Vol 110, Num 2, pp 295-303, issn 0009-7330, 9 p.Article

Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic functionBILCHICK, Kenneth C; DUNCAN, Jennifer G; RAVI, Rajashree et al.American journal of physiology. Heart and circulatory physiology. 2007, Vol 61, Num 1, issn 0363-6135, H318-H325Article

Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertensionSHIMOYAMA, Masaki; HAYASHI, Doubun; KOMURO, Issei et al.Circulation (New York, N.Y.). 2000, Vol 102, Num 16, pp 1996-2004, issn 0009-7322Article

Monoamine Oxidase A-Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure OverloadKALUDERCIC, Nina; TAKIMOTO, Eiki; PACAK, Karel et al.Circulation research. 2010, Vol 106, Num 1, pp 193-202, issn 0009-7330, 10 p.Article

Avoidance of Transient Cardiomyopathy in Cardiomyocyte-Targeted Tamoxifen-Induced MerCreMer Gene Deletion ModelsKOITABASHI, Norimichi; BEDJA, Djahida; ZAIMAN, Ari L et al.Circulation research. 2009, Vol 105, Num 1, pp 12-15, issn 0009-7330, 4 p.Article

Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathwayHSU, Steven; NAGAYAMA, Takahiro; KOITABASHI, Norimichi et al.Cardiovascular research. 2009, Vol 81, Num 2, pp 301-309, issn 0008-6363, 9 p.Article

Exposure to inhaled particulate matter impairs cardiac function in senescent miceTANKERSLEY, Clarke G; CHAMPION, Hunter C; TAKIMOTO, Eiki et al.American journal of physiology. Regulatory, integrative and comparative physiology. 2008, Vol 64, Num 1, issn 0363-6119, R252-R263Article

Control of In Vivo Contraction/Relaxation Kinetics by Myosin Binding : Protein C Protein Kinase A Phosphorylation-Dependent and -Independent RegulationNAGAYAMA, Takahiro; TAKIMOTO, Eiki; SADAYAPPAN, Sakthivel et al.Circulation (New York, N.Y.). 2007, Vol 116, Num 21, pp 2399-2408, issn 0009-7322, 10 p.Article

Phosphodiesterase regulation of nitric oxide signalingKASS, David A; TAKIMOTO, Eiki; NAGAYAMA, Takahiro et al.Cardiovascular research. 2007, Vol 75, Num 2, pp 303-314, issn 0008-6363, 12 p.Article