Screening of bioactive metabolites for pancreatic regeneration chemotherapyTAKATSUNA, Hiroshi; UMEZAWA, Kazuo.Biomedicine & pharmacotherapy. 2004, Vol 58, Num 10, pp 610-613, issn 0753-3322, 4 p.Article

Inhibition of inflammatory mediator secretion by (―)-DHMEQ in mouse bone marrow-derived macrophagesSUZUKI, Eriko; SUGIYAMA, Chie; UMEZAWA, Kazuo et al.Biomedicine & pharmacotherapy. 2009, Vol 63, Num 5, pp 351-358, issn 0753-3322, 8 p.Article

Down-regulation of TNF-α receptors by conophylline in human T-cell leukemia cellsGOHDA, Jin; INOUE, Jun-Ichiro; UMEZAWA, Kazuo et al.International journal of oncology. 2003, Vol 23, Num 5, pp 1373-1379, issn 1019-6439, 7 p.Article

Synthesis and structure-activity relationship of dehydroxymethylepoxyquinomicin analogues as inhibitors of NF-KB functionsCHAICHAROENPONG, Chanya; KATO, Kuniki; UMEZAWA, Kazuo et al.Bioorganic & medicinal chemistry. 2002, Vol 10, Num 12, pp 3933-3939, issn 0968-0896, 7 p.Article

Apoptosis in Mouse Amniotic Epithelium Is Induced by Activated Macrophages Through the TNF Receptor Type 1/TNF PathwayKOBAYASHI, Ken; UMEZAWA, Kazuo; YASUI, Masato et al.Biology of reproduction. 2011, Vol 84, Num 2, pp 248-254, issn 0006-3363, 7 p.Article

Synthesis of N-substituted N-nitrosohydroxylamines as inhibitors of mushroom tyrosinaseSHIINO, Mitsuhiro; WATANABE, Yumi; UMEZAWA, Kazuo et al.Bioorganic & medicinal chemistry. 2001, Vol 9, Num 5, pp 1233-1240, issn 0968-0896Article

Naturally occurring and synthetic inhibitors of NF-κB functionsUMEZAWA, Kazuo; ARIGA, Akiko; MATSUMOTO, Naoki et al.Anti-cancer drug design. 2000, Vol 15, Num 4, pp 239-244, issn 0266-9536Article

Efficient Cellular Uptake of the Novel NF-κB Inhibitor (-)-DHMEQ and Irreversible Inhibition of NF-κB in Neoplastic CellsSHIMADA, Chika; NINOMIYA, Yoko; SUZUKI, Eriko et al.Oncology research. 2010, Vol 18, Num 11-12, pp 529-535, issn 0965-0407, 7 p.Article

Diabetes mellitus: rational basis, clinical approach and future therapyOHGAWARA, Hisako; EDAMURA, Kazuya; KAWAKAMI, Mariko et al.Biomedicine & pharmacotherapy. 2004, Vol 58, Num 10, pp 605-609, issn 0753-3322, 5 p.Article

Biosynthesis of the lipophilic side chain in the cyclic hexadepsipeptide antibiotic IC101UMEZAWA, Kazuo; IKEDA, Yoko; NAGANAWA, Hiroshi et al.Journal of natural products (Print). 2002, Vol 65, Num 12, pp 1953-1955, issn 0163-3864, 3 p.Article

Adrenaline contributes to prenatal respiratory maturation in rat medulla-spinal cord preparationFUJII, Morimitsu; UMEZAWA, Kazuo; ARATA, Akiko et al.Brain research. 2006, Vol 1090, pp 45-50, issn 0006-8993, 6 p.Article

Antidiabetic effect of orally administered conophylline-containing plant extract on streptozotocin-treated and Goto-Kakizaki ratsFUJII, Mikio; TAKEI, Izumi; UMEZAWA, Kazuo et al.Biomedicine & pharmacotherapy. 2009, Vol 63, Num 10, pp 710-716, issn 0753-3322, 7 p.Article

Target-selective degradation of cancer-related proteins by novel photosensitizers for molecular-targeted photodynamic therapyTOSHIMA, Kazunobu; TANIMOTO, Shuho; TSUMURA, Kana et al.Cancer science. 2009, Vol 100, Num 9, pp 1581-1584, issn 1347-9032, 4 p.Article

Reversal of anticancer drug resistance by COTC based on intracellular glutathione and glyoxalase IKAMIYA, Daisuke; UCHIHATA, Yuki; ICHIKAWA, Eiko et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 4, pp 1111-1114, issn 0960-894X, 4 p.Article

A novel metal-chelating inhibitor of protein farnesyltransferaseHAMASAKI, Akiyuki; NAKA, Hayato; TAMANOI, Fuyuhiko et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 9, pp 1523-1526, issn 0960-894X, 4 p.Article

Unusual intramolecular N→O acyl group migration occurring during conjugation of (-)-DHMEQ with cysteineKOZAWA, Ikuko; KATO, Kuniki; TERUYA, Toshiaki et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 18, pp 5380-5382, issn 0960-894X, 3 p.Article

Chemosensitization and Immunosensitization of Resistant Cancer Cells to Apoptosis and Inhibition of Metastasis by the Specific NF-KB Inhibitor DHMEQKATSMAN, Alina; UMEZAWA, Kazuo; BONAVIDA, Benjamin et al.Current pharmaceutical design (Print). 2009, Vol 15, Num 7, pp 792-808, issn 1381-6128, 17 p.Article

Inactivation of NF-κB Components by Covalent Binding of (-)-Dehydroxymethylepoxyquinomicin to Specific Cysteine ResiduesYAMAMOTO, Mizuki; HORIE, Ryouichi; TAKEIRI, Masatoshi et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 18, pp 5780-5788, issn 0022-2623, 9 p.Article

Lipase-catalyzed enantio- and regioselective transformation of 3-epi-shikimic acid derivatives as the key step for the entry of polyoxygenated carbacyclesHAMADA, Manabu; HIGASHI, Toshinori; SHOJI, Mitsuru et al.Journal of molecular catalysis. B, Enzymatic. 2010, Vol 67, Num 1-2, pp 78-84, issn 1381-1177, 7 p.Article

Biological activities of α-mangostin derivatives against acidic sphingomyelinaseHAMADA, Motoko; IIKUBO, Kazuhiko; ISHIKAWA, Yuichi et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 19, pp 3151-3153, issn 0960-894X, 3 p.Article

Overexpression of phosphatidylinositol synthase enhances growth and G1 progression in NIH3T3 cellsDEGUCHI, Atsuko; SEGAWA, Kaoru; HOSAKA, Kohei et al.Japanese journal of cancer research. 2002, Vol 93, Num 2, pp 157-166, issn 0910-5050Article

Inhibition of Lysenin-induced Hemolysis by All-E-Lutein Derived from the Plant Dalbergia latifoliaCHINO MATSUI, Yuki Niwa; SUKUMWANG, Neelanun; LINUMA, Hironobu et al.Planta medica. 2012, Vol 78, Num 10, pp 957-961, issn 0032-0943, 5 p.Article

Inhibition of active HIV-1 replication by NF-κB inhibitor DHMEQMIYAKE, Ariko; ISHIDA, Takaomi; YAMAGISHI, Makoto et al.Microbes and infection. 2010, Vol 12, Num 5, pp 400-408, issn 1286-4579, 9 p.Article

BRAF^V600E promotes invasiveness of thyroid cancer cells through nuclear factor κB activationPALONA, Iryna; NAMBA, Hiroyuki; YAMASHITA, Shunichi et al.Endocrinology (Philadelphia). 2006, Vol 147, Num 12, pp 5699-5707, issn 0013-7227, 9 p.Article

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