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Mechanisms of opioid-induced pain and antinociceptive tolerance : descending facilitation and spinal dynorphinVANDERAH, Todd W; OSSIPOV, Michacl H; LAI, Josephine et al.Pain (Amsterdam). 2001, Vol 92, Num 1-2, pp 5-9, issn 0304-3959Article

Sustained morphine treatment augments prostaglandin E2-evoked calcitonin gene-related peptide release from primary sensory neurons in a PKA-dependent mannerTUMATI, Suneeta; ROESKE, William R; VANDERAH, Todd W et al.European journal of pharmacology. 2010, Vol 648, Num 1-3, pp 95-101, issn 0014-2999, 7 p.Article

The Importance of Micelle-Bound States for the Bioactivities of Bifunctional Peptide Derivatives for δ/μ Opioid Receptor Agonists and Neurokinin 1 Receptor AntagonistsYAMAMOTO, Takashi; NAIR, Padma; PORRECA, Frank et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 20, pp 6334-6347, issn 0022-2623, 14 p.Article

Design, synthesis, and biological evaluation of novel bifunctional c-terminal-modified peptides for δ/μ opioid receptor agonists and neurokinin-1 receptor antagonistsYAMAMOTO, Takashi; NAIR, Padma; PORRECA, Frank et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 12, pp 2779-2786, issn 0022-2623, 8 p.Article

Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate deliveryGARDELL, Luis R; KING, Tamara; OSSIPOV, Michael H et al.Neuroscience letters. 2006, Vol 396, Num 1, pp 44-49, issn 0304-3940, 6 p.Article

Role of NK-1 neurotransmission in opioid-induced hyperalgesiaKING, Tamara; GARDELL, Luis R; PORRECA, Frank et al.Pain (Amsterdam). 2005, Vol 116, Num 3, pp 276-288, issn 0304-3959, 13 p.Article

Triptan-Induced Latent Sensitization A Possible Basis for Medication Overuse HeadacheDE FELICE, Milena; OSSIPOV, Michael H; RUIZHONG WANG et al.Annals of neurology. 2010, Vol 67, Num 3, pp 325-337, issn 0364-5134, 13 p.Article

Medullary Pain Facilitating Neurons Mediate Allodynia in Headache-Related PainEDELMAYER, Rebecca M; VANDERAH, Todd W; KORI, Shashi H et al.Annals of neurology. 2009, Vol 65, Num 2, pp 184-193, issn 0364-5134, 10 p.Article

Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent mannerXU YUE; TUMATI, Suneeta; NAVRATILOVA, Edita et al.European journal of pharmacology. 2008, Vol 584, Num 2-3, pp 272-277, issn 0014-2999, 6 p.Article

Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancerKING, Tamara; VARDANYAN, Anna; MAJUTA, Lisa et al.Pain (Amsterdam). 2007, Vol 132, Num 1-2, pp 154-168, issn 0304-3959, 15 p.Article

Structure―activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitorsPAJOUHESH, Hassan; FENG, Zhong-Ping; PORRECA, Frank et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4153-4158, issn 0960-894X, 6 p.Article

CB₂ cannabinoid receptor mediation of antinociceptionIBRAHIM, Mohab M; RUDE, Megan L; STAGG, Nicola J et al.Pain (Amsterdam). 2006, Vol 122, Num 1-2, pp 36-42, issn 0304-3959, 7 p.Article

Morphine promotes phosphorylation of the human 6-opioid receptor at serine 363NAVRATILOVA, Edita; EATON, Miriam C; STROPOVA, Dagmar et al.European journal of pharmacology. 2005, Vol 519, Num 3, pp 212-214, issn 0014-2999, 3 p.Article

Production of paradoxical sensory hypersensitivity by α₂-Adrenoreceptor agonistsQUARTILHO, Aline; MATA, Heriberto P; IBRAHIM, Mohab M et al.Anesthesiology (Philadelphia). 2004, Vol 100, Num 6, pp 1538-1544, issn 0003-3022, 7 p.Article

Inhibition of inflammatory hyperalgesia by activation of peripheral CB₂ Cannabinoid receptorsQUARTILHO, Aline; MATA, Heriberto P; IBRAHIM, Mohab M et al.Anesthesiology (Philadelphia). 2003, Vol 99, Num 4, pp 955-960, issn 0003-3022, 6 p.Article

Peripheral mechanisms of pain and analgesiaSTEIN, Christoph; CLARK, J. David; OH, Uhtaek et al.Brain research reviews. 2009, Vol 60, Num 1, pp 90-113, issn 0165-0173, 24 p.Conference Paper

Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral κ-opioid receptorsVANDERAH, Todd W; LARGENT-MILNES, Tally; SCHTEINGART, Claudio et al.European journal of pharmacology. 2008, Vol 583, Num 1, pp 62-72, issn 0014-2999, 11 p.Article

Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathwaysVERA-PORTOCARRERO, Louis P; ZHANG, En-Tan; KING, Tamara et al.Pain (Amsterdam). 2007, Vol 129, Num 1-2, pp 35-45, issn 0304-3959, 11 p.Article

Chronic morphine-mediated adenylyl cyclase superactivation is attenuated by the Raf-1 inhibitor, GW5074XU YUE; VARGA, Eva V; STROPOVA, Dagmar et al.European journal of pharmacology. 2006, Vol 540, Num 1-3, pp 57-59, issn 0014-2999, 3 p.Article

Antinociception depends on the presence of G protein γ₂-subunits in brainVARGA, Eva V; HOSOHATA, Keiko; BORYS, Dariusz et al.European journal of pharmacology. 2005, Vol 508, Num 1-3, pp 93-98, issn 0014-2999, 6 p.Article

Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cordMARSHALL, Timothy M; HERMAN, David S; LARGENT-MILNES, Tally M et al.Pain (Amsterdam). 2012, Vol 153, Num 1, pp 86-94, issn 0304-3959, 9 p.Article

Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic painDE FELICE, Milena; SANOJA, Raul; FIELDS, Howard L et al.Pain (Amsterdam). 2011, Vol 152, Num 12, pp 2701-2709, issn 0304-3959, 9 p.Article

A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: Therapeutic opportunity for treating skeletal painJIMENEZ-ANDRADE, Juan Miguel; MANTYH, William G; BLOOM, Aaron P et al.Bone (New York, NY). 2010, Vol 46, Num 2, pp 306-313, issn 8756-3282, 8 p.Article

Improving Metabolic Stabitity by Glycosylation: Bifunctional Peptide Derivatives That Are Opioid Receptor Agonists and Neurokinin 1 Receptor AntagonistsYAMAMOTO, Takashi; NAIR, Padma; PORRECA, Frank et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 16, pp 5164-5175, issn 0022-2623, 12 p.Article