pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs : Kinetic analysis of quinidine efflux in situVARMA, Manthena V. S; PANCHAGNULA, Ramesh.Journal of pharmaceutical sciences. 2005, Vol 94, Num 12, pp 2632-2643, issn 0022-3549, 12 p.Article

Pharmacokinetics of Voriconazole Administered Concomitantly with Fluconazole and Population-Based Simulation for Sequential UseDAMLE, Bharat; VARMA, Manthena V; WOOD, Nolan et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 11, pp 5172-5177, issn 0066-4804, 6 p.Article

Enhanced oral paclitaxel absorption with vitamin E-TPGS : Effect on solubility and permeability in vitro, in situ and in vivoVARMA, Manthena V. S; PANCHAGNULA, Ramesh.European journal of pharmaceutical sciences. 2005, Vol 25, Num 4-5, pp 445-453, issn 0928-0987, 9 p.Article

Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeabilityVARMA, Manthena V. S; PANCHAGNULA, Ramesh.Journal of pharmaceutical sciences. 2005, Vol 94, Num 8, pp 1694-1704, issn 0022-3549, 11 p.Article

Prediction of Pharmacokinetics and Drug-Drug Interactions When Hepatic Transporters are InvolvedRUI LI; BARTON, Hugh A; VARMA, Manthena V et al.Clinical pharmacokinetics. 2014, Vol 53, Num 8, pp 659-678, issn 0312-5963, 20 p.Article

Rapid and selective UV spectrophotometric and RP-HPLC methods for dissolution studies of oxybutynin immediate-release and controlled-release formulationsVARMA, Manthena V. S; KAUSHAL, Aditya M; GARG, Sanjay et al.Journal of pharmaceutical and biomedical analysis. 2004, Vol 36, Num 3, pp 669-674, issn 0731-7085, 6 p.Article

Simultaneous determination of digoxin and permeability markers in rat in situ intestinal perfusion samples by RP-HPLCVARMA, Manthena V. S; KAPOOR, Namita; SARKAR, Mahua et al.Journal of chromatography. B. 2004, Vol 813, Num 1-2, pp 347-352, issn 1570-0232, 6 p.Article

Influence of micro-environmental pH on the gel layer behavior and release of a basic drug from various hydrophilic matricesVARMA, Manthena V. S; KAUSHAL, Aditya M; GARG, Sanjay et al.Journal of controlled release. 2005, Vol 103, Num 2, pp 499-510, issn 0168-3659, 12 p.Article

pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs. 1. Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samplesVARMA, Manthena V. S; SARKAR, Mahua; KAPOOR, Namita et al.Journal of chromatography. B. 2005, Vol 816, Num 1-2, pp 243-249, issn 1570-0232, 7 p.Article

Reversed-phase liquid chromatography with ultraviolet detection for simultaneous quantitation of indinavir and propranolol from ex-vivo rat intestinal permeability studiesPANCHAGNULA, Ramesh; BANSAL, Tripta; VARMA, Manthena V. S et al.Journal of chromatography. B. 2004, Vol 806, Num 2, pp 277-282, issn 1570-0232, 6 p.Article

The Intestinal Absorption of a Prodrug of the mGlu2/3 Receptor Agonist LY354740 is Mediated by PEPT1: In Situ Rat Intestinal Perfusion StudiesERIKSSON, André H; VARMA, Manthena V. S; PERKINS, Everett J et al.Journal of pharmaceutical sciences. 2010, Vol 99, Num 3, pp 1574-1581, issn 0022-3549, 8 p.Article

Physicochemical Determinants of Human Renal ClearanceVARMA, Manthena V. S; BO FENG; OBACH, R. Scott et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 15, pp 4844-4852, issn 0022-2623, 9 p.Article

Mechanistic Modeling to Predict the Transporter-and Enzyme-Mediated Drug-Drug Interactions of RepaglinideVARMA, Manthena V. S; YURONG LAI; KIMOTO, Emi et al.Pharmaceutical research. 2013, Vol 30, Num 4, pp 1188-1199, issn 0724-8741, 12 p.Article

Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug InteractionsVARMA, Manthena V. S; LAI, Yurong; BO FENG et al.Pharmaceutical research. 2012, Vol 29, Num 10, pp 2860-2873, issn 0724-8741, 14 p.Article

Transepithelial Transport of the Group II Metabotropic Glutamate 2/3 Receptor Agonist (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740) and Its Prodrug (1S,2S,5R,6S)-2-[(2'S)-(2'-Amino)propionyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY544344)VARMA, Manthena V. S; ERIKSSON, André H; SAWADA, Geri et al.Drug metabolism and disposition. 2009, Vol 37, Num 1, pp 211-220, issn 0090-9556, 10 p.Article

Development of a New Permeability Assay Using Low-Efflux MDCKII CellsLI DI; WHITNEY-PICKETT, Carrie; REYNER, Eric L et al.Journal of pharmaceutical sciences. 2011, Vol 100, Num 11, pp 4974-4985, issn 0022-3549, 12 p.Article

Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatinBI, Yi-An; XI QIU; ROTTER, Charles J et al.Biopharmaceutics & drug disposition. 2013, Vol 34, Num 8, pp 452-461, issn 0142-2782, 10 p.Article

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass EliminationVARMA, Manthena V. S; OBACH, R. Scott; ROTTER, Charles et al.Journal of medicinal chemistry (Print). 2010, Vol 53, Num 3, pp 1098-1108, issn 0022-2623, 11 p.Article