Novel role of ouabain as a cystogenic factor in autosomal dominant polycystic kidney diseaseBLANCO, Gustavo; WALLACE, Darren P.American journal of physiology. Renal physiology. 2013, Vol 74, Num 3, issn 1931-857X, F797-F812Article

Return of the secretory kidneyGRANTHAM, Jared J; WALLACE, Darren P.American journal of physiology. Renal physiology. 2002, Vol 51, Num 1, pp F1-F9, issn 1931-857XArticle

Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferationNGUYEN, Anh-Nguyet T; WALLACE, Darren P; BLANCO, Gustavo et al.Journal of the American Society of Nephrology. 2007, Vol 18, Num 1, pp 46-57, issn 1046-6673, 12 p.Article

Smac-Mimetic―Induced Epithelial Cell Death Reduces the Growth of Renal CystsFAN, Lucy X; XIA ZHOU; SWEENEY, William E et al.Journal of the American Society of Nephrology. 2013, Vol 24, Num 12, pp 2010-2022, issn 1046-6673, 13 p.Article

Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cellsYAMAGUCHI, Tamio; HEMPSON, Scott J; REIF, Gail A et al.Journal of the American Society of Nephrology. 2006, Vol 17, Num 1, pp 178-187, issn 1046-6673, 10 p.Article

Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/ Na⁺,K⁺,2Cl^- Co-transporter-dependent cystic dilationMAGENHEIMER, Brenda S; JOHN, Patricia L. St; ISOM, Kathryn S et al.Journal of the American Society of Nephrology. 2006, Vol 17, Num 12, pp 3424-3437, issn 1046-6673, 14 p.Article

Urinary excretion of monocyte chemoattractant protein-1 in autosomal dominant polycystic kidney diseaseDANXIA ZHENG; WOLFE, Marieka; COWLEY, Benjamin D et al.Journal of the American Society of Nephrology. 2003, Vol 14, Num 10, pp 2588-2595, issn 1046-6673, 8 p.Article

Identification of a forskolin-like molecule in human renal cystsPUTNAM, William C; SWENSON, Sarah M; REIF, Gail A et al.Journal of the American Society of Nephrology. 2007, Vol 18, Num 3, pp 934-943, issn 1046-6673, 10 p.Article

Adrenergic regulation of salt and fluid secretion in human medullary collecting duct cellsWALLACE, Darren P; REIF, Gail; HEDGE, Anne-Marie et al.American journal of physiology. Renal physiology. 2004, Vol 56, Num 4, pp F639-F648, issn 1931-857XArticle

Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneysSCHWIEBERT, Erik M; WALLACE, Darren P; GRANTHAM, Jared J et al.American journal of physiology. Renal physiology. 2002, Vol 51, Num 4, pp F763-F775, issn 1931-857XArticle

Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathwaysJANSSON, Kyle; NGUYEN, Anh-Nguyet T; MAGENHEIMER, Brenda S et al.American journal of physiology. Renal physiology. 2012, Vol 72, Num 4, issn 1931-857X, F982-F990Article

Periostin induces proliferation of human autosomal dominant polycystic kidney cells through α_v-integrin receptorWALLACE, Darren P; QUANTE, Megan T; REIF, Gail A et al.American journal of physiology. Renal physiology. 2008, Vol 64, Num 5, issn 1931-857X, F1463-F1471Article

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneysYAMAGUCHI, Tamio; NAGAO, Shizuko; WALLACE, Darren P et al.Kidney international. 2003, Vol 63, Num 6, pp 1983-1994, issn 0085-2538, 12 p.Article

Calmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl^― secretion by human autosomal dominant polycystic kidney cellsPINTO, Cibele S; REIF, Gail A; NIVENS, Emily et al.American journal of physiology. Renal physiology. 2012, Vol 72, Num 5, issn 1931-857X, F1412-F1424Article

PPAR-γ agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney diseaseYOSHIHARA, Daisuke; KURAHASHI, Hiroki; MORITA, Miwa et al.American journal of physiology. Renal physiology. 2011, Vol 69, Num 2, issn 1931-857X, F465-F474Article

KCa3.1 potassium channels are critical for cAMP-dependent chloride secretion and cyst growth in autosomal-dominant polycystic kidney disease. CommentaryALPER, Seth L; ALBAQUMI, Mamdouh; SRIVASTAVA, Shekhar et al.Kidney international. 2008, Vol 74, Num 6, issn 0085-2538, 699-702, 740-749 [14 p.]Article

Increased water intake decreases progression of polycystic kidney disease in the PCK ratNAGAO, Shizuko; NISHII, Kazuhiro; KATSUYAMA, Makoto et al.Journal of the American Society of Nephrology. 2006, Vol 17, Num 8, pp 2220-2227, issn 1046-6673, 8 p.Article

The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosisBUCHHOLZ, Bjoern; KLANKE, Bernd; HIRTH, Peter et al.Nephrology, dialysis, transplantation (Print). 2011, Vol 26, Num 11, pp 3458-3465, issn 0931-0509, 8 p.Article

Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1ALCALAY, Neal I; SHARMA, Madhulika; VASSMER, Dianne et al.American journal of physiology. Renal physiology. 2008, Vol 64, Num 6, issn 1931-857X, F1725-F1734Article

Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cellsBELIBI, Franck A; REIF, Gail; WALLACE, Darren P et al.Kidney international. 2004, Vol 66, Num 3, pp 964-973, issn 0085-2538, 10 p.Article

Sulfonylurea-sensitive K⁺ transport is involved in Cl^- secretion and cyst growth by cultured ADPKD cellsSULLIVAN, Lawrence P; WALLACE, Darren P; GOVER, Tony et al.Journal of the American Society of Nephrology. 2002, Vol 13, Num 11, pp 2619-2627, issn 1046-6673, 9 p.Article

The effect of caffeine on renal epithelial cells from patients with autosomal dominant polycystic kidney diseaseBELIBI, Franck A; WALLACE, Darren P; YAMAGUCHI, Tamio et al.Journal of the American Society of Nephrology. 2002, Vol 13, Num 11, pp 2723-2729, issn 1046-6673, 7 p.Article

cAMP-dependent fluid secretion in rat inner medullary collecting ductsWALLACE, Darren P; ROME, Lorraine A; SULLIVAN, Lawrence P et al.American journal of physiology. Renal physiology. 2001, Vol 49, Num 6, pp F1019-F1029, issn 1931-857XArticle

Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signalingKUGITA, Masanori; NISHII, Kazuhiro; NAGAO, Shizuko et al.American journal of physiology. Renal physiology. 2011, Vol 69, Num 1, issn 1931-857X, F177-F188Article

Ouabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferationNGUYEN, Anh-Nguyet T; JANSSON, Kyle; SANCHEZ, Gladis et al.American journal of physiology. Renal physiology. 2011, Vol 70, Num 4, issn 1931-857X, F897-F906Article