Pharmacokinetics of heparin V: in vivo and in vitro factors affecting the relationship between concentration and anticoagulant effect of heparin in rat plasmaWHITFIELD, L. R; LEVY, G.Journal of pharmaceutical sciences. 1983, Vol 72, Num 10, pp 1141-1146, issn 0022-3549Article

Multiple-dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG-CoA reductase, in healthy subjectsCILLA, D. D; WHITFIELD, L. R; GIBSON, D. M et al.Clinical pharmacology and therapeutics. 1996, Vol 60, Num 6, pp 687-695, issn 0009-9236Article

Pharmacometric analysis of the effect of furosemide on suramin pharmacokineticsPISCITELLI, S. C; FORREST, A; LUSH, R. M et al.Pharmacotherapy. 1997, Vol 17, Num 3, pp 431-437, issn 0277-0008Article

Phase I pharmacokinetic and pharmacodynamic study of a new anthrapyrazole, CI-937 (DUP937)ERLICHMAN, C; MOORE, M; KERR, I. G et al.Cancer research (Baltimore). 1991, Vol 51, Num 23, pp 6317-6322, issn 0008-5472, 1Article

Pharmacokinetic and toxicity scaling of the antitumor agents amsacrine and CI-921, a new analogue, in mice, rats, rabbits, dogs, and humansPAXTON, J. W; KIM, S. N; WHITFIELD, L. R et al.Cancer research (Baltimore). 1990, Vol 50, Num 9, pp 2692-2697, issn 0008-5472, 6 p.Article

High-performance liquid chromatographic assay for CI-980, a novel 1-deaza-7,8-dihydropteridine anticancer agent, in human plasma and urineBULLEN, W. W; WHITFIELD, L. R; WALTER, G. A et al.Journal of chromatography. B, Biomedical applications. 1995, Vol 668, Num 1, pp 141-151Article

Effect of food on the bioavailability of atorvastatin, and HMG-CoA reductase inhibitorRADULOVIC, L. L; CILLA, D. D; POSVAR, E. L et al.Journal of clinical pharmacology. 1995, Vol 35, Num 10, pp 990-994, issn 0091-2700Article

Metabolic disposition of trimetrexate, a nonclassical dihydrofolate reductase inhibitor, in rat and dogWONG, B. K; WOOLF, T. F; TSUN CHANG et al.Drug metabolism and disposition. 1990, Vol 18, Num 6, pp 980-986, issn 0090-9556, 7 p.Article

High-performance liquid chromatographic assay for the experimental anticancer agent oxantrazoleFRANK, S. K; MATHIESEN, D. A; WHITFIELD, L. R et al.Journal of chromatography. 1987, Vol 419, pp 225-232, issn 0021-9673Article

Effect of age and gender on pharmacokinetics of atorvastatin in humansGIBSON, D. M; BRON, N. J; RICHENS, A et al.Journal of clinical pharmacology. 1996, Vol 36, Num 3, pp 242-246, issn 0091-2700Article

Pharmacodynamic effects and pharmacokinetics of atorvastatin after administration to normocholesterolemic subjects in the morning and eveningCILLA, D. D; GIBSON, D. M; WHITFIELD, L. R et al.Journal of clinical pharmacology. 1996, Vol 36, Num 7, pp 604-609, issn 0091-2700Article

Development of a radioimmunoassay for the anthrapyrazole chemotherapy agent CI-937 and the pharmacokinetics of CI-937 in ratsNORDBLOM, G. D; PACHLA, L. A; TSUNG CHANG et al.Cancer research (Baltimore). 1989, Vol 49, Num 19, pp 5345-5351, issn 0008-5472Article

Clinical risk factors for prolonged PT/PTT in abdominal sepsis patients treated with moxalactam or tobramycin plus clindamycinBAXTER, J. G; MARBLE, D. A; WHITFIELD, L. R et al.Annals of surgery. 1985, Vol 201, Num 1, pp 96-102, issn 0003-4932Article

Atorvastatin transport in the Caco-2 cell model: Contributions of P-glycoprotein and the proton-monocarboxylic acid Co-transporterXIAOCHUN WU; WHITFIELD, L. R; STEWART, B. H et al.Pharmaceutical research. 2000, Vol 17, Num 2, pp 209-215, issn 0724-8741Article

Clinical pharmacokinetics of 3-deazaguaninePENDYALA, L; CREAVEN, P. J; WHITFIELD, L. R et al.Cancer chemotherapy and pharmacology. 1991, Vol 29, Num 1, pp 33-36, issn 0344-5704Article

Pharmacokinetics of heparin. VII: Effect of pregnancy on the relationship between concentration and anticoagulant action of heparin in ratsWHITFIELD, L. R; WILKENFELD, C; LEVY, G et al.Journal of pharmaceutical sciences. 1984, Vol 73, Num 1, pp 72-74, issn 0022-3549Article

High-performance liquid chromatographic assay for trimetrexate in human plasmaBULLEN, W. W; CHANG, T; WHITFIELD, L. R et al.Journal of chromatography. Biomedical applications. 1990, Vol 526, Num 1, pp 266-272, issn 0378-4347Article

Cimetidine does not alter atorvastatin pharmacokinetics or LDL-cholesterol reductionSTERN, R. H; GIBSON, D. M; WHITFIELD, L. R et al.European journal of clinical pharmacology. 1998, Vol 53, Num 6, pp 475-478, issn 0031-6970Article

Development, validation, and interlaboratory comparison of an HMG-CoA reductase inhibition assay for quantitation of atorvastatin in plasma matricesSHUM, Y. Y; NAIJIA HUANG; WALTER, G et al.Therapeutic drug monitoring. 1998, Vol 20, Num 1, pp 41-49, issn 0163-4356Article

Tolerance and pharmacokinetics of single-dose atorvastatin, a potent inhibitor of HMG-CoA reductase, in healthy subjectsPOSVAR, E. L; RADULOVIC, L. L; CILLA, D. D et al.Journal of clinical pharmacology. 1996, Vol 36, Num 8, pp 728-731, issn 0091-2700Article

A high-performance liquid chromatographic assay for CI-973, a new anticancer platinum diamine complex, in human plasma and urine ultrafiltratesBULLEN, W. W; ANDRESS, L. D; TSUN CHANG et al.Cancer chemotherapy and pharmacology. 1992, Vol 30, Num 3, pp 193-198, issn 0344-5704Article

Phase I clinical and pharmacokinetic study of trimetrexate using a daily ×5 scheduleSTEWART, J. A; MCCORMACK, J. J; DELAP, R. J et al.Cancer research (Baltimore). 1988, Vol 48, Num 17, pp 5029-5035, issn 0008-5472Article

Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductaseWHITFIELD, L. R; STERN, R. H; SEDMAN, A. J et al.European journal of drug metabolism and pharmacokinetics. 2000, Vol 25, Num 2, pp 97-101, issn 0378-7966Article

Trimetrexate efficacy and pharmacokinetics during treatment of refractory Pneumocystis carinii pneumonia in an infant with severe combined immunodeficiency disease. CommentarySMIT, M. J. M; DE GROOT, R; VAN DONGEN, J. J. M et al.The Pediatric infectious disease journal. 1990, Vol 9, Num 3, pp 212-215, issn 0891-3668, 4 p.Article

Determination of low levels of the stereoisomers of leucovorin and 5-methyltetrahydrofolate in plasma using a coupled chiral-achiral high-performance liquid chromatographic system with post-chiral column peak compressionSILAN, L; JADAUD, P; WHITFIELD, L. R et al.Journal of chromatography. Biomedical applications. 1990, Vol 532, Num 2, pp 227-236, issn 0378-4347Article