Modification of natural, double-helical DNA by antitumor cis- and trans-[Cl₂(Me₂SO₄)₄Ru] in cell-free mediaNOVDKOVD, Olga; HOFR, Ctirad; BRABEC, Viktor et al.Biochemical pharmacology. 2000, Vol 60, Num 12, pp 1761-1771, issn 0006-2952Article

Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt^II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligandKASPARKOVA, Jana; SUCHANKOVA, Tereza; HALAMIKOVA, Anna et al.Biochemical pharmacology. 2010, Vol 79, Num 4, pp 552-564, issn 0006-2952, 13 p.Article

Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophilesNAJAJREH, Yousef; ARDELI-TZARAF, Yael; BRABEC, Viktor et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 15, pp 4674-4683, issn 0022-2623, 10 p.Article

DNA interactions of 2-pyrrolinodoxorubicin, a distinctively more potent daunosamine-modified analogue of doxorubicinSTEPANKOVA, Jana; STUDENOVSKY, Martin; MALINA, Jaroslav et al.Biochemical pharmacology. 2011, Vol 82, Num 3, pp 227-235, issn 0006-2952, 9 p.Article

Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studiesNAJAJREH, Yousef; KHAZANOV, Elena; JAWBRY, Seba et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 15, pp 4665-4673, issn 0022-2623, 9 p.Article

Amide-Based Prodrugs of Spermidine-Bridged Dinuclear Platinum. Synthesis, DNA Binding, and Biological ActivityHEGMANS, Alexander; KASPARKOVA, Jana; VRANA, Oldrich et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 7, pp 2254-2260, issn 0022-2623, 7 p.Article

DNA interactions of platinum anticancer drugs. Recent advances and mechanisms of actionBRABEC, Viktor; KASPARKOVA, Jana.Metal compounds in cancer chemotherapy. 2005, pp 187-218, isbn 81-7736-277-1, 1Vol, 32 p.Book Chapter

DNA interactions of dinuclear Ru^II arene antitumor complexes in cell-free mediaNOUAKOVA, Olga; NAZAROV, Alexey A; HARTINGER, Christian G et al.Biochemical pharmacology. 2009, Vol 77, Num 3, pp 364-374, issn 0006-2952, 11 p.Article

Conformation and recognition of DNA modified by a new antitumor dinuclear Pt^II complex resistant to decomposition by sulfur nucleophilesZERZANKOVA, Lenka; SUCHANKOVA, Tereza; VRANA, Oldrich et al.Biochemical pharmacology. 2010, Vol 79, Num 2, pp 112-121, issn 0006-2952, 10 p.Article

Transplatin is cytotoxic when photoactivated : Enhanced formation of DNA cross-linksHERINGOVA, Pavla; WOODS, Julie; MACKAY, Fiona S et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 26, pp 7792-7798, issn 0022-2623, 7 p.Article

Mechanistic insights into antitumor effects of new dinuclear cis Pt^II complexes containing aromatic linkersZERZANKOVA, Lenka; KOSTRHUNOVA, Hana; VOJTISKOVA, Marie et al.Biochemical pharmacology. 2010, Vol 80, Num 3, pp 344-351, issn 0006-2952, 8 p.Article

DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans -[{PtCl₂(NH₃)}₂(piperazine)]BRABEC, Viktor; CHRISTOFIS, Petros; SLAMOUVA, Martina et al.Biochemical pharmacology. 2007, Vol 73, Num 12, pp 1887-1900, issn 0006-2952, 14 p.Article

Reaction of Zn₇metallothionein with cis-and trans -[Pt (N -donor )₂Cl₂] anticancer complexes : trans-Pt^II complexes retain their N-donor ligandsKNIPP, Markus; KAROTKI, Andrei V; CHESNOV, Serge et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 17, pp 4075-4086, issn 0022-2623, 12 p.Article

DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligandPROKOP, Radim; KASPARKOVA, Jana; NOVAKOVA, Olga et al.Biochemical pharmacology. 2004, Vol 67, Num 6, pp 1097-1109, issn 0006-2952, 13 p.Article

Studies of the Mechanism of Action of Platinum(II) Complexes with Potent Cytotoxicity in Human Cancer CellsKRAUSE-HEUER, Anwen M; GRÜNERT, Renate; BEDNARSKI, Patrick J et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 17, pp 5474-5484, issn 0022-2623, 11 p.Article

Cytotoxicity, Cellular Uptake, and DNA Interactions of New Monodentate Ruthenium(II) Complexes Containing Terphenyl ArenesBUGARCIC, Tijana; NOVAKOVA, Olga; HALAMIKOVA, Anna et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 17, pp 5310-5319, issn 0022-2623, 10 p.Article

Synthesis, Biophysical Studies, and Antiproliferative Activity of Platinum(II) Complexes Having 1,2-Bis(aminomethyl)carbobicyclic LigandsDE MIER-VINUE, Jordi; GAY, Marina; COLUCCIA, Mauro et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 3, pp 424-431, issn 0022-2623, 8 p.Article

High-throughput screening identifies novel agents eliciting hypersensitivity in fanconi pathway-deficient cancer cellsGALLMEIER, Eike; HUCL, Tomas; BRODY, Jonathan R et al.Cancer research (Baltimore). 2007, Vol 67, Num 5, pp 2169-2177, issn 0008-5472, 9 p.Article

3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agentsPLSIKOVA, Jana; JANOVEC, Ladislav; BRABEC, Viktor et al.European journal of medicinal chemistry. 2012, Vol 57, pp 283-295, issn 0223-5234, 13 p.Article

DNA Interactions of Monofunctional Organometallic Osmium(II) Antitumor Complexes in Cell-Free MediaKOSTRHUNOVA, Hana; FLORIAN, Jakub; NOVAKOVA, Olga et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 12, pp 3635-3643, issn 0022-2623, 9 p.Article

Structural characterization, DNA interactions, and cytotoxicity of new transplatin analogues containing one aliphatic and one planar heterocyclic amine ligandRAMOS-LIMA, Francisco J; VRANA, Oldrich; QUIROGA, Adoracion G et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 8, pp 2640-2651, issn 0022-2623, 12 p.Article

Recognition of DNA modified by antitumor cisplatin by latent and active protein p53FOJTA, Miroslav; PIVONKOVA, Hana; BRAZDOVA, Marie et al.Biochemical pharmacology. 2003, Vol 65, Num 8, pp 1305-1316, issn 0006-2952, 12 p.Article