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Inhibition of potentially lethal DNA damage repair in human tumor cells by β-lapachone, an activator of topoisomerase IBOOTHMAN, D. A; TRASK, D. K; PARDEE, A. B et al.Cancer research (Baltimore). 1989, Vol 49, Num 3, pp 605-612, issn 0008-5472, 8 p.Article

β-Lapachone analogs with enhanced antiproliferative activityRIOS-LUCI, Carla; BONIFAZI, Evelyn L; LEON, Leticia G et al.European journal of medicinal chemistry. 2012, Vol 53, pp 264-274, issn 0223-5234, 11 p.Article

β-Lapachone: synthesis of derivatives and activities in tumor modelsSCHAFFNER-SABBA, K; SCHMIDT-RUPPIN, K. H; WEHRLI, W et al.Journal of medicinal chemistry (Print). 1984, Vol 27, Num 8, pp 990-994, issn 0022-2623Article

Applications of counter-current chromatography in organic synthesis purification of heterocyclic derivatives of lapacholSILVA, Raphael S. F; LEITAO, Gilda G; BRUM, Thiago B et al.Journal of chromatography. 2007, Vol 1151, Num 1-2, pp 197-202, issn 0021-9673, 6 p.Conference Paper

1,3-Azoles from ortho-naphthoquinones: Synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosisMOURA, Kelly C. G; CARNEIRO, Paula F; ALMEIDA DA SILVA, Pedro E et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 21, pp 6482-6488, issn 0968-0896, 7 p.Article

Comparative studies of the effects of Tabebuia avellanedae bark extract and β-lapachone on the hematopoietic response of tumour-bearing miceQUEIROZ, Mary L. S; VALADARES, Marize C; TORELLO, Cristiane O et al.Journal of ethnopharmacology. 2008, Vol 117, Num 2, pp 228-235, issn 0378-8741, 8 p.Article

Toxicological Assessment of Beta-lapachone on Organs from Pregnant and Non-pregnant RatsRODRIGUES DE AKNEIDA, Edvaldo; SANTOS LUCENA, Flavia Raquel; PASSILONGO DA SILVA, Aldo Cezar et al.PTR. Phytotherapy research. 2009, Vol 23, Num 9, pp 1276-1280, issn 0951-418X, 5 p.Article

Potentiation of halogenated pyrimidine radiosensitizers in human carcinoma cells by β-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione), a novel DNA repair inhibitorBOOTHMAN, D. A; GREER, S; PARDEE, A. B et al.Cancer research (Baltimore). 1987, Vol 47, Num 20, pp 5361-5366, issn 0008-5472Article

Effects of β-lapachone, a new anticancer candidate, on cytochrome P450-mediated drug metabolismIN SOOK KIM; YUN KIM; TAE HWAN KWAK et al.Cancer chemotherapy and pharmacology. 2013, Vol 72, Num 3, pp 699-702, issn 0344-5704, 4 p.Article

β-lapachone, a specific competitive inhibitor of ligand binding to the glucocorticoid receptorSCHMIDT, T. J; MILLER-DIENER, A; LITWACK, G et al.The Journal of biological chemistry (Print). 1984, Vol 259, Num 15, pp 9536-9543, issn 0021-9258Article

Induction of egr-1 is associated with anti-metastatic and anti-invasive ability of β-lapachone in human hepatocarcinoma cellsKIM, Sung Ok; KWON, Jae Im; JEONG, Yong Kee et al.Bioscience, biotechnology, and biochemistry. 2007, Vol 71, Num 9, pp 2169-2176, issn 0916-8451, 8 p.Article

Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of ARQ 501 (β-lapachone) in plasma and tumors from nu/nu mouse xenograftsSAVAGE, R. E; HALL, T; BRESCIANO, K et al.Journal of chromatography. B. 2008, Vol 872, Num 1-2, pp 148-153, issn 1570-0232, 6 p.Article

β -Lapachone -containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cellsBLANCO, Elvin; BEY, Erik A; YING DONG et al.Journal of controlled release. 2007, Vol 122, Num 3, pp 365-374, issn 0168-3659, 10 p.Conference Paper

Synthesis of New o-Quinone Methides from β3-Lapachone AnaloguesBAPTISTA FERREIRA, Sabrina; GOMES GONZAGA, Daniel Tadeu; DE CARVALHO DA SILVA, Fernando et al.Synlett (Stuttgart). 2011, Num 11, pp 1623-1625, issn 0936-5214, 3 p.Article

Electrochemistry of β-lapachone and its diazoderivative : Relevance to their compared antimicrobial activitiesDE ABREU, Fabiane C; FERREIRA, Danielle C. M; WADHAWAN, Jay et al.Electrochemistry communications. 2005, Vol 7, Num 7, pp 767-772, issn 1388-2481, 6 p.Article

β-Lapachone reduces endotoxin-induced macrophage activation and lung edema and mortalityTZENG, Huei-Ping; HO, Feng-Ming; CHAO, Kuo-Fang et al.American journal of respiratory and critical care medicine. 2003, Vol 168, Num 1, pp 85-91, issn 1073-449X, 7 p.Article

Trypanosoma cruzi: Insights into naphthoquinone effects on growth and proteinase activityBOURGUIGNON, Saulo C; CAVALCANTI, Danielle F. B; DE PINHO, Rosa T et al.Experimental parasitology. 2011, Vol 127, Num 1, pp 160-166, issn 0014-4894, 7 p.Article

Compatibility of the antitumoral β-lapachone with different solid dosage forms excipientsCUNHA, Marcflio S. S; MARTINEZ-PACHECO, Ramon; LANDIN, Mariana et al.Journal of pharmaceutical and biomedical analysis. 2007, Vol 45, Num 4, pp 590-598, issn 0731-7085, 9 p.Article

Combined directed metalation - cross coupling strategies. A regiospecific route to heteroring-annelated ortho-naphthoquinones and a short synthesis of β-lapachoneBRANDAO, M. A. F; BRAGA DE OLIVEIRA, A; SNIECKUS, V et al.Tetrahedron letters. 1993, Vol 34, Num 15, pp 2437-2440, issn 0040-4039Article

The encapsulation of β-lapachone in 2-hydroxypropyl-β-cyclodextrin inclusion complex into liposomes: A physicochemical evaluation and molecular modeling approachCAVALCANTI, Isabella M. F; MENDONCA, Elisângela A. M; SANTOS-MAGALHAES, Nereide S et al.European journal of pharmaceutical sciences. 2011, Vol 44, Num 3, pp 332-340, issn 0928-0987, 9 p.Article

Dissolution rate enhancement of the novel antitumoral β-lapachone by solvent change precipitation of microparticlesCUNHA-FILHO, Marcflio S. S; MARTINEZ-PACHECO, Ramon; LANDIN, Mariana et al.European journal of pharmaceutics and biopharmaceutics. 2008, Vol 69, Num 3, pp 871-877, issn 0939-6411, 7 p.Article

Comparison of antibacterial and antifungal activities of lapachol and β-lapachoneGUIRAUD, P; STEIMAN, R; CAMPOS-TAKAKI, G.-M et al.Planta medica. 1994, Vol 60, Num 4, pp 373-374, issn 0032-0943Article

Electron and hydrogen atom transfer mechanisms for the photoreduction of o-quinones. Visible light induced photoreactions of β-lapachone with amines, alcohols, and amino alcoholsXIAOHONG CI; SILVEIRA DA SILVA, R; NICODEM, D et al.Journal of the American Chemical Society. 1989, Vol 111, Num 4, pp 1337-1343, issn 0002-7863Article

Redox cycling of β-lapachone and related o-naphthoquinones in the presence of dihydrolipoamide and oxygenMOLINA PORTELA, M. P; STOPPANI, A. O. M.Biochemical pharmacology. 1996, Vol 51, Num 3, pp 275-283, issn 0006-2952Article

Activation of NAD(P)H:Quinone Oxidoreductase 1 Prevents Arterial Restenosis by Suppressing Vascular Smooth Muscle Cell ProliferationKIM, Sun-Yee; NAM HO JEOUNG; LEE, Ki-Up et al.Circulation research. 2009, Vol 104, Num 7, pp 842-850, issn 0009-7330, 9 p.Article

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