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The synthesis and evaluation of cyclic ureas as hiv protease inhibitors : Modifications of the P1/P1' residuesPATEL, M; BACHELER, L. T; RAYNER, M. M et al.Bioorganic & medicinal chemistry letters (Print). 1998, Vol 8, Num 7, pp 823-828, issn 0960-894XArticle

Cyclic HIV protease inhibitors : Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureasLAM, P. Y. S; RU, Y; LI, L et al.Journal of medicinal chemistry (Print). 1996, Vol 39, Num 18, pp 3514-3525, issn 0022-2623Article

A quantitative structure-activity relationship study on some HIV-1 protease inhibitors using molecular connectivity indexGAYATHRI, P; PANDE, V; SIVAKUMAR, R et al.Bioorganic & medicinal chemistry. 2001, Vol 9, Num 11, pp 3059-3063, issn 0968-0896Article

The synthesis of symmetrical and unsymmetrical P1/P1' cyclic ureas as HIV protease inhibitorsPATEL, M; KALTENBACH, R. F; REID, C et al.Bioorganic & medicinal chemistry letters (Print). 1998, Vol 8, Num 9, pp 1077-1082, issn 0960-894XArticle

Enthalpy-related interaction parameters in H/D isotopically distinguishable aqueous solutions of tetramethylurea cyclic derivatives at 298.15 KLVANOV, Evgeniy V; BATOV, Dmitriy V.Thermochimica acta. 2011, Vol 523, Num 1-2, pp 253-257, issn 0040-6031, 5 p.Article

Quantitative structure-activity relationship studies on cyclic cyanoguanidines acting as HIV-1 protease inhibitorsGUPTA, S. P; SURESH BABU, M.Bioorganic & medicinal chemistry. 1999, Vol 7, Num 11, pp 2549-2553, issn 0968-0896Article

Synthesis of C2-symmetric guanidino-sugars as potent inhibitors of glycosidasesLE MERRER, Y; GAUZY, L; GRAVIER-PELLETIER, C et al.Bioorganic & medicinal chemistry. 2000, Vol 8, Num 2, pp 307-320, issn 0968-0896Article

Excess chemical potentials, partial molar enthalpies and entropies in binary aqueous acetone and tetramethyl urea at 25°CCHEN, Daniel H. C; PUI MING CHU; TANAKA, Steven Hiroshi et al.Fluid phase equilibria. 2000, Vol 175, Num 1-2, pp 35-43, issn 0378-3812Article

Synthesis of 1,2,4-triazolo[4,3-a](1,3)diazepines. Reactions of hexahydro-1H-1,3-diazepin-2-one hydrazone hydroiodide with acyl reagents. VII: 1,2,4-triazolo[4,3-a]diazacycloalkanesKREZEL, I.Pharmazie. 1993, Vol 48, Num 3, pp 189-192, issn 0031-7144Article

Stereoisomers of cyclic urea HIV-1 protease inhibitors : Synthesis and binding affinitiesKALTENBACH, R. F; NUGIEL, D. A; LAM, P. Y. S et al.Journal of medicinal chemistry (Print). 1998, Vol 41, Num 25, pp 5113-5117, issn 0022-2623Article

Carbonylation of functionalized diamine diols to cyclic ureas: application to derivatives of DMP 450DARKO, Ampofo K; CURRAN, F. Chris; COPIN, Chloé et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 22, issn 0040-4020, 3961, 3976-3983 [9 p.]Article

Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitorsKALTENBACH, Robert F; PATEL, Mona; WRIGHT, Matthew R et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 4, pp 605-608, issn 0960-894X, 4 p.Article

Nonsymmetrically substituted cyclic urea HIV protease inhibitorsWILKERSON, W. W; DAX, S; CHEATHAM, W. W et al.Journal of medicinal chemistry (Print). 1997, Vol 40, Num 25, pp 4079-4088, issn 0022-2623Article

Cyclic HIV protease inhibitors : Design and synthesis of orally bioavailable, pyrazole P2/P2' cyclic ureas with improved potencyQI HAN; CHANG, C.-H; RENHUA LI et al.Journal of medicinal chemistry (Print). 1998, Vol 41, Num 12, pp 2019-2028, issn 0022-2623Article

HIV protease inhibitory bis-benzamide cyclic ureas : A quantitative structure-activity relationship analysisWILKERSON, W. W; AKAMIKE, E; CHEATHAM, W. W et al.Journal of medicinal chemistry (Print). 1996, Vol 39, Num 21, pp 4299-4312, issn 0022-2623Article

Design and synthesis of highly constrained Factor Xa inhibitors: Amidine-substituted bis(benzoyl)-[1,3]-diazepan-2-ones and bis(benzylidene)-bis(gem-dimethyl)cycloketonesJIAN CUI; CRICH, David; JOHNSON, Michael E et al.Bioorganic & medicinal chemistry. 2003, Vol 11, Num 16, pp 3379-3392, issn 0968-0896, 14 p.Article

Cyclic urea amides : HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIVJADHAV, P. K; ALA, P; WOERNER, F. J et al.Journal of medicinal chemistry (Print). 1997, Vol 40, Num 2, pp 181-191, issn 0022-2623Article

Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitorBÄCKBRO, K; LÖWGREN, S; ÖSTERLUND, K et al.Journal of medicinal chemistry (Print). 1997, Vol 40, Num 6, pp 898-902, issn 0022-2623Article

P-glycoprotein effects of cyclic urea HIV protease inhibitor dmp 323 in competitional absorption studiesRICHTER, Martin; GYEMANT, Nora; MOLNAR, Joséf et al.Archiv der Pharmazie (Weinheim). 2006, Vol 339, Num 11, pp 625-628, issn 0365-6233, 4 p.Article

A mechanistic study of 3-aminoindazole cyclic urea HIV-1 protease inhibitors using comparative QSARGARG, Rajni; BHHATARAI, Barun.Bioorganic & medicinal chemistry. 2004, Vol 12, Num 22, pp 5819-5831, issn 0968-0896, 13 p.Article

Unsymmetrical cyclic ureas as HIV-1 protease inhibitors : Novel biaryl indazoles as P2/P2' substituentsPATEL, M; RODGERS, J. D; MCHUGH, R. J et al.Bioorganic & medicinal chemistry letters (Print). 1999, Vol 9, Num 22, pp 3217-3220, issn 0960-894XArticle

Increased antiviral activity of cyclic urea HIV protease inhibitors by modifying the P1/P1' substituentsKALTENBACH, R. F; KLABE, R. M; CORDOVA, B. C et al.Bioorganic & medicinal chemistry letters (Print). 1999, Vol 9, Num 15, pp 2259-2262, issn 0960-894XArticle

Synthesis of 7-membered cyclic hydroxyguanidines : Novel HIV-1 protease inhibitorsJADHAV, P. K; WOERNER, F. J; MAN, H.-W et al.Bioorganic & medicinal chemistry letters (Print). 1997, Vol 7, Num 17, pp 2145-2148, issn 0960-894XArticle

Nonsymmetric P2/P2' cyclic urea HIV protease inhibitors. Structure-activity relationship, bioavailability, and resistance profile of monoindazole-substituted P2 analoguesDE LUCCA, G. V; KIM, U. T; ERICKSON-VIITANEN, S et al.Journal of medicinal chemistry (Print). 1998, Vol 41, Num 13, pp 2411-2423, issn 0022-2623Article

Potent cyclic urea HIV protease inhibitors with 3-aminoindazole P2/P2' groupsRODGERS, J. D; JOHNSON, B. L; HAISHENG WANG et al.Bioorganic & medicinal chemistry letters (Print). 1998, Vol 8, Num 7, pp 715-720, issn 0960-894XArticle

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