Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068YIBING YAN; SERRA, Violeta; WAGLE, Marie-Claire et al.Clinical cancer research (Print). 2013, Vol 19, Num 24, pp 6976-6986, issn 1078-0432, 11 p.Article

Akt Inhibitor Akt-IV Blocks Virus Replication through an Akt-Independent MechanismDUNN, Ewan F; FEARNS, Rachel; CONNOR, John H et al.Journal of virology. 2009, Vol 83, Num 22, pp 11665-11672, issn 0022-538X, 8 p.Article

Akt Inhibitor MK2206 Prevents Influenza pH1N1 Virus Infection In VitroDENISOVA, Oxana V; SÖDERHOLM, Sandra; NYMAN, Tuula A et al.Antimicrobial agents and chemotherapy. 2014, Vol 58, Num 7, pp 3689-3696, issn 0066-4804, 8 p.Article

Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor ModelsJIE LIN; SAMPATH, Deepak; LEE, Leslie B et al.Clinical cancer research (Print). 2013, Vol 19, Num 7, pp 1760-1772, issn 1078-0432, 13 p.Article

New thiazole carboxamides as potent inhibitors of Akt kinasesSHAOHUA CHANG; ZHANG ZHANG; XIAOXI ZHUANG et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 2, pp 1208-1212, issn 0960-894X, 5 p.Article

Pyrazolopyrimidines as dual Akt/p70S6K inhibitorsRICE, Kenneth D; KIM, Moon H; COSTANZO, Simona et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 8, pp 2693-2697, issn 0960-894X, 5 p.Article

Ceramide induces cell cycle arrest and upregulates p27kip in nasopharyngeal carcinoma cellsZHU, Xiao-Feng; LIU, Zong-Chao; XIE, Bin-Fen et al.Cancer letters. 2003, Vol 193, Num 2, pp 149-154, issn 0304-3835, 6 p.Article

Akt Plays a Critical Role in Replication of Nonsegmented Negative-Stranded RNA VirusesMINGHAO SUN; FUENTES, Sandra M; TIMANI, Khalid et al.Journal of virology. 2008, Vol 82, Num 1, pp 105-114, issn 0022-538X, 10 p.Article

Elevation of Receptor Tyrosine Kinases by Small Molecule AKT Inhibitors in Prostate Cancer Is Mediated by Pim-1BO CEN; MAHAJAN, Sandeep; WENXUE WANG et al.Cancer research (Chicago, Ill.). 2013, Vol 73, Num 11, pp 3402-3411, issn 0008-5472, 10 p.Article

The Akt/PKB pathway : molecular target for cancer drug discoveryCHENG, Jin Q; LINDSLEY, Craig W; CHENG, George Z et al.Oncogene (Basingstoke). 2005, Vol 24, Num 50, pp 7482-7492, issn 0950-9232, 11 p.Article

Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/AktFOSTER, K. S. J; MCCRARY, W. J; ROSS, J. S et al.Oncogene (Basingstoke). 2006, Vol 25, Num 33, pp 4605-4612, issn 0950-9232, 8 p.Article

Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous LeukemiaKONOPLEVA, Marina Y; WALTER, Roland B; HONGBO LU et al.Clinical cancer research (Print). 2014, Vol 20, Num 8, pp 2226-2235, issn 1078-0432, 10 p.Article

Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363LAMOUREUX, Francois; THOMAS, Christian; CRAFTER, Claire et al.Clinical cancer research (Print). 2013, Vol 19, Num 4, pp 833-844, issn 1078-0432, 12 p.Article

KEAP1-Dependent Synthetic Lethality Induced by AKT and TXNRD1 Inhibitors in Lung CancerBINGBING DAI; YOO, Suk-Young; BINGLIANG FANG et al.Cancer research (Chicago, Ill.). 2013, Vol 73, Num 17, pp 5532-5543, issn 0008-5472, 12 p.Article

Biomarkers of Response to Akt Inhibitor MK-2206 in Breast CancerSANGAI, Takafumi; AKCAKANAT, Argun; MERIC-BERNSTAM, Funda et al.Clinical cancer research (Print). 2012, Vol 18, Num 20, pp 5816-5828, issn 1078-0432, 13 p.Article

Akt inhibitors induce apoptosis in chronic lymphocytic leukemia cellsDE FRIAS, Mercè; IGLESIAS-SERRET, Daniel; COSIALLS, Ana M et al.Haematologica (Roma). 2009, Vol 94, Num 12, pp 1698-1707, issn 0390-6078, 10 p.Article

The two TORCs and aktBHASKAR, Prashanth T; HAY, Nissim.Developmental cell. 2007, Vol 12, Num 4, pp 487-502, issn 1534-5807, 16 p.Article

Molecular determinants of Akt-induced keratinocyte transformationSEGRELLES, C; MORAL, M; BALLESTIN, C et al.Oncogene (Basingstoke). 2006, Vol 25, Num 8, pp 1174-1185, issn 0950-9232, 12 p.Article

MK-2206, an AKT Inhibitor, Promotes Caspase-Independent Cell Death and Inhibits Leiomyoma GrowthSEFTON, Elizabeth C; WENAN QIANG; SERNA, Vanida et al.Endocrinology (Philadelphia). 2013, Vol 154, Num 11, pp 4046-4057, issn 0013-7227, 12 p.Article

Minireview : AKT in thyroid tumorigenesis and progressionSHINOHARA, Motoo; YUN JAE CHUNG; SAJI, Motoyasu et al.Endocrinology (Philadelphia). 2007, Vol 148, Num 3, pp 942-947, issn 0013-7227, 6 p.Article

eEF-2 Kinase Dictates Cross-Talk between Autophagy and Apoptosis Induced by Akt Inhibition, Thereby Modulating Cytotoxicity of Novel Akt Inhibitor MK-2206YAN CHENG; XINGCONG REN; YI ZHANG et al.Cancer research (Chicago, Ill.). 2011, Vol 71, Num 7, pp 2654-2663, issn 0008-5472, 10 p.Article

Clinical and Translational Studies of a Phase II Trial of the Novel Oral Akt Inhibitor Perifosine in Relapsed or Relapsed/ Refractory Waidenström's MacroglobulinemiaGHOBRIAL, Irene M; ROCCARO, Aldo; AZAB, Feda et al.Clinical cancer research (Print). 2010, Vol 16, Num 3, pp 1033-1041, issn 1078-0432, 9 p.Article

Akt/protein kinase BABRAHAM, Edward.Critical care medicine. 2005, Vol 33, Num 12, pp S420-S422, issn 0090-3493, SUPArticle

Identification of 3'-hydroxymelanetin and liquiritigenin as akt protein kinase inhibitorsYANG, Hye-Young; LEE, Hong-Sub; KO, Jong-Hee et al.Journal of microbiology and biotechnology. 2006, Vol 16, Num 9, pp 1384-1391, issn 1017-7825, 8 p.Article

Lipoteichoic acid promotes nuclear accumulation of β-catenin via AKT in human gingival fibroblastsGUTIERREZ-VENEGAS, Gloria; CARDOSO-JIMENEZ, Patricia.International immunopharmacology (Print). 2011, Vol 11, Num 9, pp 1278-1284, issn 1567-5769, 7 p.Article