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Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic LeukemiaBYRD, John C; FURMAN, Richard R; JONES, Jeffrey A et al.The New England journal of medicine. 2013, Vol 369, Num 1, pp 32-42, issn 0028-4793, 11 p.Article

Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγJANDA, Elzbieta; PALMIERI, Camillo; ROSSI, Annalisa et al.Blood. 2011, Vol 117, Num 24, pp 6520-6531, issn 0006-4971, 12 p.Article

Coding-region alterations in BTK do not universally cause X-linked agammaglobulinemiaABBOTT, Jordan K; OCHS, Hans D; GELFAND, Erwin W et al.Journal of allergy and clinical immunology. 2013, Vol 132, Num 5, pp 1246-1248, issn 0091-6749, 3 p.Article

Btk is a positive regulator in the TREM-1/DAP12 signaling pathwayORMSBY, Tereza; SCHLECKER, Eva; HOREJSI, Václav et al.Blood. 2011, Vol 118, Num 4, pp 936-945, issn 0006-4971, 10 p.Article

Breaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemiaHUTCHINSON, Claire V; DYER, Martin J. S.British journal of haematology. 2014, Vol 166, Num 1, pp 12-22, issn 0007-1048, 11 p.Article

Ibrutinib, Obinutuzumab, Idelalisib, and Beyond: Review of Novel and Evolving Therapies for Chronic Lymphocytic LeukemiaCHUNG, Clement; LEE, Rosetta.Pharmacotherapy. 2014, Vol 34, Num 12, pp 1298-1316, issn 0277-0008, 19 p.Article

Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitorMACGLASHAN, Donald; HONIGBERG, Lee A; SMITH, Ashley et al.International immunopharmacology (Print). 2011, Vol 11, Num 4, pp 475-479, issn 1567-5769, 5 p.Article

TLR signaling and effector functions are intact in XLA neutrophilsMARRON, Thomas U; ROHR, Kaileen; MARTINEZ-GALLO, Monica et al.Clinical immunology (Orlando, Fla. Print). 2010, Vol 137, Num 1, pp 74-80, issn 1521-6616, 7 p.Article

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myelomaTAI, Yu-Tzu; CHANG, Betty Y; CEA, Michele et al.Blood. 2012, Vol 120, Num 9, pp 1877-1887, issn 0006-4971, 11 p.Article

Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase InhibitorLICHUAN LIU; HALLADAY, Jason S; KUEBLER, Peter et al.Drug metabolism and disposition. 2011, Vol 39, Num 10, pp 1840-1849, issn 0090-9556, 10 p.Article

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765HERMAN, Sarah E. M; GORDON, Amber L; HAMDY, Ahmed et al.Blood. 2011, Vol 117, Num 23, pp 6287-6296, issn 0006-4971, 10 p.Article

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in miceKIL, Laurens P; DE BRUIJN, Marjolein J. W; LOO, Pieter Fokko Van et al.Blood. 2012, Vol 119, Num 16, pp 3744-3756, issn 0006-4971, 13 p.Article

Ibrutinib pour traiter la leucémie lymphocytaire chronique = Ibrutinib for chronic lymphocytic leukemiaThe Medical letter on drugs and therapeutics (Edition française). 2014, Vol 36, Num 10, pp 37-38, issn 0253-8512, 2 p.Article

The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemiaDE ROOIJ, Martin F. M; KUIL, Annemieke; GEEST, Christian R et al.Blood. 2012, Vol 119, Num 11, pp 2590-2594, issn 0006-4971, 5 p.Article

Neutrophil development and function critically depend on Bruton tyrosine kinase in a mouse model of X-linked agammaglobulinemiaFIEDLER, Katja; SINDRILARU, Anca; TERSZOWSKI, Grzegorz et al.Blood. 2011, Vol 117, Num 4, pp 1329-1339, issn 0006-4971, 11 p.Article

Monozygous twins with a microdeletion syndrome involving BTK, DDP1, and two other genes; evidence of intact dendritic cell development and TLR responsesJYONOUCHI, Harumi; GENG, Lee; TÖRÜNER, Gökce A et al.European journal of pediatrics. 2008, Vol 167, Num 3, pp 317-321, issn 0340-6199, 5 p.Article

Bruton tyrosine kinase mediates TLR9-dependent human dendritic cell activationLOUGARIS, Vassilios; BARONIO, Manuela; VITALI, Massimiliano et al.Journal of allergy and clinical immunology. 2014, Vol 133, Num 6, pp 1644-1650, issn 0091-6749, 7 p.Article

Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell MalignanciesADVANI, Ranjana H; BUGGY, Joseph J; SUKBUNTHERNG, Juthamas et al.Journal of clinical oncology. 2013, Vol 31, Num 1, pp 88-94, issn 0732-183X, 7 p.Article

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathwaysMUELLER, Helena; STADTMANN, Anika; VAN AKEN, Hugo et al.Blood. 2010, Vol 115, Num 15, pp 3118-3127, issn 0006-4971, 10 p.Article

Characterization of ibrutinib-sensitive and -resistant mantle lymphoma cellsJIAO MA; PIN LU; AILIN GUO et al.British journal of haematology. 2014, Vol 166, Num 6, pp 849-861, issn 0007-1048, 13 p.Article

Bruton tyrosine kinase inhibitors: a promising novel targeted treatment for B cell lymphomasAALIPOUR, Amin; ADVANI, Ranjana H.British journal of haematology. 2013, Vol 163, Num 4, pp 436-443, issn 0007-1048, 8 p.Article

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivoPONADER, Sabine; CHEN, Shih-Shih; BUGGY, Joseph J et al.Blood. 2012, Vol 119, Num 5, pp 1182-1189, issn 0006-4971, 8 p.Article

Clinical, immunological and molecular characteristics of 37 iranian patients with X-linked agammaglobulinemiaAGHAMOHAMMADI, Asghar; FIORINI, Maurilia; REZAEI, Nima et al.International archives of allergy and immunology. 2006, Vol 141, Num 4, pp 408-414, issn 1018-2438, 7 p.Article

Validation d'une méthode d'analyse génétique de la maladie de Bruton = Validation of a Bruton's disease genetic analysis methodRODRIGUEZ, C; D'AUDIGIER, C; BERTRAND, V et al.Annales de biologie clinique (Paris). 2006, Vol 64, Num 5, pp 445-449, issn 0003-3898, 5 p.Article