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Novel isoxazole polycyclic aromatic hydrocarbons as DNA-intercalating agentsRESCIFINA, Antonio; VARRICA, Maria Giulia; CARNOVALE, Caterina et al.European journal of medicinal chemistry. 2012, Vol 51, pp 163-173, issn 0223-5234, 11 p.Article

Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activityMASURIER, Nicolas; DEBITON, Eric; CANITROT, Damien et al.European journal of medicinal chemistry. 2012, Vol 52, pp 137-150, issn 0223-5234, 14 p.Article

DNA intercalative potential of marketed drugs testing positive in in vitro cytogenetics assaysSNYDER, Ronald D; EWING, Douglas; HENDRY, Lawrence B et al.Mutation research. Genetic toxicology and environmental mutagenesis. 2006, Vol 609, Num 1, pp 47-59, issn 1383-5718, 13 p.Article

Crystal structure of 3-hydroxy methyl 4,6-dimethoxy-9-phenylsulfonyl-carbazoleGOVINDASAMY, L; RAJAKANNAN, V; VELMURUGAN, D et al.Crystal research and technology (1979). 2003, Vol 38, Num 2, pp 182-192, issn 0232-1300, 11 p.Article

Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase IIOPPEGARD, Lisa M; OUGOLKOV, Andrei V; LUCHINI, Doris N et al.European journal of pharmacology. 2009, Vol 602, Num 2-3, pp 223-229, issn 0014-2999, 7 p.Article

Toward a greater appreciation of noncovalent chemical/DNA interactions : Application of biological and computational approachesSNYDER, Ronald D; HENDRY, Lawrence B.Environmental and molecular mutagenesis (Print). 2005, Vol 45, Num 2-3, pp 100-105, issn 0893-6692, 6 p.Article

A rapid and sensitive method for the screening of DNA intercalating antibioticsFURLAN, Renata Ligia A; GARRIDO, Leandro M; BRUMATTI, Gabriela et al.Biotechnology letters. 2002, Vol 24, Num 21, pp 1807-1813, issn 0141-5492, 7 p.Article

Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modelingNGUYEN LE, Thanh; SU HUI YANG; BIKRAM KHADKA, Daulat et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 14, pp 4399-4404, issn 0968-0896, 6 p.Article

Lovastatin enhances the genotoxicity of doxorubicin in Chinese hamster V79 cells via noncovalent DNA bindingSNYDER, Ronald D.Drug and chemical toxicology (New York, NY. 1978). 2009, Vol 32, Num 1, pp 17-20, issn 0148-0545, 4 p.Article

Five-coordinated oxovanadium(IV) complexes derived from amino acids and ciprofloxacin : Synthesis, spectral, antimicrobial, and DNA interaction approachPATEL, M. N; PATEL, S. H; CHHASATIA, M. R et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 24, pp 6494-6500, issn 0960-894X, 7 p.Article

Naphthalimide intercalators with chiral amino side chains : Effects of chirality on DNA binding, photodamage and antitumor cytotoxicityQING YANG; PENG YANG; XUHONG QIAN et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 23, pp 6210-6213, issn 0960-894X, 4 p.Article

Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitorsDAVID-CORDONNIER, Marie-Hélène; HILDEBRAND, Marie-Paule; BALDEYROU, Brigitte et al.European journal of medicinal chemistry. 2007, Vol 42, Num 6, pp 752-771, issn 0223-5234, 20 p.Article

Evaluation of DNA intercalation potential of pharmaceuticals and other chemicals by cell-based and three-dimensional computational approachesSNYDER, Ronald D; EWING, Douglas E; HENDRY, Lawrence B et al.Environmental and molecular mutagenesis (Print). 2004, Vol 44, Num 2, pp 163-173, issn 0893-6692, 11 p.Article

Novel antitumor indenoindole derivatives targeting DNA and topoisomerase IIBAL, Christine; BALDEYROU, Brigitte; WIERZBICKI, Michel et al.Biochemical pharmacology. 2004, Vol 68, Num 10, pp 1911-1922, issn 0006-2952, 12 p.Article

DNA targeting of two new antitumour rebeccamycin derivativesFACOMPRE, Michaël; BALDEYROU, Brigitte; BAILLY, Christian et al.European journal of medicinal chemistry. 2002, Vol 37, Num 12, pp 925-932, issn 0223-5234, 8 p.Article

Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: Design, synthesis, DNA binding and antitumor cell cytotoxicityLEMSTER, Thomas; PINDUR, Ulf; LENGLET, Gaelle et al.European journal of medicinal chemistry. 2009, Vol 44, Num 8, pp 3235-3252, issn 0223-5234, 18 p.Article

CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylationMAHALE, Sachin; AUBRY, Carine; WILSON, A. James et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 16, pp 4272-4278, issn 0960-894X, 7 p.Article

An aminoacridine derivative for radionuclide therapy : DNA-binding properties studied in a novel cell-free in vitro assayKULLBERG, Erika Bohl; STENERLÖW, Bo; GHIRMAI, Senait et al.International journal of oncology. 2005, Vol 27, Num 5, pp 1355-1360, issn 1019-6439, 6 p.Article

Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus ZyzzyaDIJOUX, Marie-Geneviève; SCHNABEL, Peter C; CARDELLINA, John H et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 21, pp 6035-6044, issn 0968-0896, 10 p.Article

An optical DNA-based biosensor for the analysis of bioactive constituents with application in drug and herbal drug screeningMINUNNI, Maria; TOMBELLI, Sara; MASCINI, Marco et al.Talanta (Oxford). 2005, Vol 65, Num 2, pp 578-585, issn 0039-9140, 8 p.Conference Paper

TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cellsLIU, Yu-Peng; CHEN, Hui-Ling; TZENG, Cherng-Chyi et al.Breast cancer research and treatment. 2013, Vol 138, Num 2, pp 383-393, issn 0167-6806, 11 p.Article

Design, synthesis, and biological evaluation of novel N-γ-carboline arylsulfonamides as anticancer agentsJING CHEN; TAO LIU; RUI WU et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 24, pp 8478-8484, issn 0968-0896, 7 p.Article

DNA binding of benzophenanthridine compounds sanguinarine versus ethidium: Comparative binding and thermodynamic profile of intercalationHOSSAIN, Maidul; GOPINATHA SURESH KUMAR.Journal of chemical thermodynamics. 2009, Vol 41, Num 6, pp 764-774, issn 0021-9614, 11 p.Article

Synthesis and evaluation of 9-anilinothiazolo[5,4-b]quinoline derivatives as potential antitumoralsRODRIGUEZ-LOAIZA, Pilar; QUINTERO, Angelina; RODRIGUEZ-SOTRES, Rogelio et al.European journal of medicinal chemistry. 2004, Vol 39, Num 1, pp 5-10, issn 0223-5234, 6 p.Article

Synthesis and DNA interaction of a mixed proflavine-phenanthroline Tröger baseBALDEYROU, Brigitte; TARDY, Christelle; BAILLY, Christian et al.European journal of medicinal chemistry. 2002, Vol 37, Num 4, pp 315-322, issn 0223-5234, 8 p.Article

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